- An efficient procedure for the synthesis of 3-aryl-4-methoxy-2(5H)-furanones by using the microwave-promoted Suzuki-Miyaura coupling reactions
-
The Suzuki-Miyaura coupling reactions of 3-bromo-2(5H)-furanones with a variety of arylboronic acids, promoted by microwave heating, efficiently generate 3-aryl-2(5H)-furanones. This remarkably rapid process serves as the foundation for a simple method to
- Song, Young Seob,Lee, Yun-Jeong,Kim, Bum Tae,Heo, Jung-Nyoung
-
-
Read Online
- Compound, as well as preparation method and application thereof
-
The application discloses a compound of which the structure is represented as the following formula, wherein R1 is selected from any one of F, Cl, Br, C1-C5 alkyl group, and a group having the structure as the formula (1), n = 0, 1, 2, 3, 4 or 5; the R2 is selected from any one of a group having the structure as the formula (1), a group having the structure as the formula (2), and a group having the structure as the formula (3). The compound has simple preparation method, can be used as a neuraminidase inhibitor, and has excellent antivirus activity.
- -
-
Paragraph 0312-0316
(2020/03/17)
-
- A facile synthesis, antibacterial activity of pulvinone and its derivatives
-
Pulvinone and several 3-fluoro-4-morpholino substituted pulvinone derivatives were synthesized in five steps from a common precursor, phenyl acetic acid. Most of synthetic morpholine substituted pulvinones showed inhibitory activity against Esherichia col
- Xu, Hai-Wei,Xu, Chao,Fan, Zi-Qi,Zhao, Ling-Jie,Liu, Hong-Min
-
p. 737 - 739
(2013/02/25)
-
- Synthesis of 2(5H)-furanones via oxidative ring expansion of 4-hydroxy-2-cyclobutenones
-
A new method to reduce cyclobutenediones towards 4-hydroxy-2-cyclobutenones was established. The latter compounds gave rise to new 5-halo-2(5H)-furanones by reaction with halogenating agents via a cationic ring-opening-ring-closure mechanism.
- Verniest, Guido,De Kimpe, Norbert
-
p. 947 - 950
(2007/10/03)
-
- Synthesis of (E)- and (Z)-Pulvinones
-
Two new routes to pulvinones have been developed, one of which involves a novel Wittig reaction.For the first time, members of the E-series, including the parent (E)-pulvinone, are reported and the structural elucidation of the geometric isomers is descri
- Campbell, Alexander C.,Maidment, Maurice S.,Pick, John H.,Stevenson, Donald F. M.
-
p. 1567 - 1576
(2007/10/02)
-