100074-56-4

Upstream product

• 1878-66-6 4-chlorophenylacetic Acid 
• 100074-30-4 phenylacetic acid 
• 69556-70-3 4-methoxy-5H-furan-2-one 
• 71387-05-8 4-methoxy-3-bromo-furan-2(5H)-one 
• 1679-18-1 4-Chlorophenylboronic acid 
• 853660-91-0 5-chloro-3-(4-chloro-phenyl)-4-methoxy-5H-furan-2-one 
• 100074-43-9 3-(4-chlorophenyl)-4-hydroxyfuran-2(5H)-one 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 1421237-09-3 C₂₂H₂₁ClFNO₅ 
• 1421237-26-4 C₂₂H₁₉ClFNO₄ 
• 1421237-27-5 C₂₂H₁₉ClFNO₄ 
• 100074-69-9 5-Bromo-3-(4-chloro-phenyl)-4-methoxy-5H-furan-2-one 

Relevant academic research and scientific papers

An efficient procedure for the synthesis of 3-aryl-4-methoxy-2(5H)-furanones by using the microwave-promoted Suzuki-Miyaura coupling reactions

The Suzuki-Miyaura coupling reactions of 3-bromo-2(5H)-furanones with a variety of arylboronic acids, promoted by microwave heating, efficiently generate 3-aryl-2(5H)-furanones. This remarkably rapid process serves as the foundation for a simple method to

Compound, as well as preparation method and application thereof

The application discloses a compound of which the structure is represented as the following formula, wherein R1 is selected from any one of F, Cl, Br, C1-C5 alkyl group, and a group having the structure as the formula (1), n = 0, 1, 2, 3, 4 or 5; the R2 is selected from any one of a group having the structure as the formula (1), a group having the structure as the formula (2), and a group having the structure as the formula (3). The compound has simple preparation method, can be used as a neuraminidase inhibitor, and has excellent antivirus activity.

A facile synthesis, antibacterial activity of pulvinone and its derivatives

Pulvinone and several 3-fluoro-4-morpholino substituted pulvinone derivatives were synthesized in five steps from a common precursor, phenyl acetic acid. Most of synthetic morpholine substituted pulvinones showed inhibitory activity against Esherichia col

Synthesis of 2(5H)-furanones via oxidative ring expansion of 4-hydroxy-2-cyclobutenones

A new method to reduce cyclobutenediones towards 4-hydroxy-2-cyclobutenones was established. The latter compounds gave rise to new 5-halo-2(5H)-furanones by reaction with halogenating agents via a cationic ring-opening-ring-closure mechanism.

Synthesis of (E)- and (Z)-Pulvinones

Two new routes to pulvinones have been developed, one of which involves a novel Wittig reaction.For the first time, members of the E-series, including the parent (E)-pulvinone, are reported and the structural elucidation of the geometric isomers is descri