cas 1003-07-2, thiazol-3-one | Articles data ｜lookchem

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1003-07-2

Articles about 1003-07-2Total 6 be found

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Imidazolo-5-YL-2anilino-pyrimidines as agents for the inhibition of the cell proliffration
Compounds of the formula (I): wherein R1, R2, R3, R4, R5, R6, p, q, and n are as defined within and a pharmaceutically acceptable salts and in vivo hydrolysable esters are described. Also described are processes for their preparation and their use as medicaments, particularly medicaments for producing a cell cycle inhibitory (anti-cell-proliferation) effect in a warm-blooded animal, such as man.
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Page/Page column 37-38

(2010/02/05)

Isothiazolones lower plasma levels of lipoprotein(a)
Plasma levels of Lp(a) are lowered by administering an isothiazolone having the general structure STR1 where A is a monocyclic or bicyclic ring which may contain up to 3 heteroatoms selected from O, S, and N; R1 and R2 are substituen
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(2008/06/13)

Isothiazolones
Isothiazolones having the general structure STR1 where A is a monocyclic or bicyclic ring which may contain up to 3 heteroatoms selected from O, S, and N; R1 and R2 are substituent groups such as alkyl, alkoxy, hydroxy, nitro, cyano, amino, and carboxy; and R5 is alkyl, cycloalkyl, phenyl, and Het. The isothiazolones are useful as anti-retroviral agents, anti-inflammatory agents, and anti-atherosclerotic agents.
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(2008/06/13)

A General Synthesis of N-Substituted Isothiazol-3(2H)-ones
A general route to the synthesis of N-substituted isothiazol-3(2H)-ones (4a-i) is described which proceeds via trichloroacetic acid-mediated ring closure of N-substituted (Z)-3-(benzylsulfinyl)propenamides (15a-i).
Beeley, Nigel R. A.,Harwood, Laurence M.,Hedger, Paul C.
p. 2245 - 2252
(2007/10/02)

Nitrosamine-free 3-isothiazolone
Nitrosamine-free 3-isothiazolone biocidal compositions suitable for applications where substantial human or animal contact is anticipated, their method of use and process of preparation are disclosed.
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(2008/06/13)

Microbicidal microemulsion
Disclosed are dilutable oil-in-water microemulsions of low water soluble microbicidal isothiazolones and their method of preparation.
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(2008/06/13)

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Chemical Properties

Melting Point: 74-75 °C
Boiling Point: 86.333 °C at 760 mmHg
Flash Point:6.014 °C
Density: 1.433 g/cm³
Solubility:Chloroform (Slightly), Ethyl Acetate (Slightly)
Storage Temp.:2-8°C
Vapor Pressure: 59.568mmHg at 25°C
Refractive Index: 1.614
PKA: 9.12±0.20(Predicted)
PSA: 61.10000
LogP: 0.43640

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