10075-38-4

Basic information

• Product Name: (Z)-1,3-Dichloro-2-butene
• Synonyms: (Z)-1,3-Dichloro-2-butene
• CAS NO: 10075-38-4
• Molecular Formula: C₄H₆Cl₂
• Molecular Weight: 125
• Mol File: 10075-38-4.mol

Chemical Properties

• Melting Point: -27.02°C (estimate)
• Boiling Point: 130.15°C
• Flash Point: 33.9°C
• Appearance: /
• Density: 1.1605
• Refractive Index: 1.4735
• CAS DataBase Reference: (Z)-1,3-Dichloro-2-butene(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-1,3-Dichloro-2-butene(10075-38-4)
• EPA Substance Registry System: (Z)-1,3-Dichloro-2-butene(10075-38-4)

Safety Data

• Hazardous Substances Data: 10075-38-4(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
(Z)-1,3-Dichloro-2-butene is used as an intermediate in the synthesis of other organic chemicals and pharmaceuticals, playing a crucial role in the production of various compounds.
Used in Organic Chemistry Reactions:
(Z)-1,3-Dichloro-2-butene is used as a reagent in organic chemistry reactions, particularly in the production of various types of polymers, contributing to the development of new materials and products.
Used in Pharmaceutical Industry:
(Z)-1,3-Dichloro-2-butene is utilized in the pharmaceutical industry as a key component in the synthesis of certain drugs, highlighting its importance in the development of new medications.
Safety Precautions:
Due to its highly flammable and reactive nature, (Z)-1,3-Dichloro-2-butene should be handled with caution and stored in a tightly sealed container. It is essential to follow proper safety protocols and regulations when working with this chemical to ensure the safety of individuals and the environment.

InChI:InChI=1S/C4H6Cl2/c1-4(6)2-3-5/h2H,3H2,1H3/b4-2-

Upstream product

• 689-97-4 3-buten-1-yne 
• 37428-46-9 (Z)-3-chloro-2-but-en-1-ol 
• 7415-31-8 (E)-1,3-dichloro-2-butene 
• 37428-46-9 3-chloro-2-buten-1-ol 
• 126-99-8 chloroprene 
• 926-57-8 1,3-dichloro-2-butene 
• 2768-41-4 4-methoxy-but-2-yne 
• 3355-17-7 1-chloro-2-butyne 
• 7647-01-0 hydrogenchloride 
• 37428-53-8 (E)-3-chloro-but-2-en-1-ol 

Downstream Products

• 18062-77-6 2-(3-chloro-but-2t-enyl)-4-methyl-phenol 
• 72008-98-1 (+/-)-3-(3-chloro-but-2t-enyl)-2-methyl-4-oxo-cyclohex-2-enecarboxylic acid ethyl ester 
• 2431-50-7 2,3,4-trichloro-1-butene 
• 87-68-3 Hexachlorobutadiene 
• 126-99-8 chloroprene 
• 16485-99-7 (chloro-3 propene-2)ylphosphonate de diethyle 
• 115198-06-6 1-phenyl-5-chlorohex-4-en-1-yne 
• 127-19-5 N,N-dimethyl acetamide 
• 83305-52-6 N,N-dimethyl-α-(3-chloro-2-butenyl)acetoacetamide 
• 22515-82-8 1-pentene-3-one ethylene acetal 
• 91191-69-4 (+/-)-<1α(Z),4aβ>-1-(3-Chloro-2-butenyl)-3,4,4a,5,6,7-hexahydro-1,4a-dimethyl-2(1H)-naphthalenone 
• 67986-43-0 (E)-5-Chloro-2-cyclohex-1-enyl-hex-4-enoic acid dimethylamide 
• 13138-51-7 1,2,3,3-tetrachlorobutane 
• 7647-01-0 hydrogenchloride 

Relevant articles and documents

Synthesis and evaluation of chlorinated substrate analogues for farnesyl diphosphate synthase

Substrate analogues for isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), where the C3 methyl groups were replaced by chlorine, were synthesized and evaluated as substrates for avian farnesyl diphosphate synthase (FPPase). The IPP analogue (3-ClIPP) was a cosubstrate when incubated with dimethylallyl diphosphate (DMAPP) or geranyl diphosphate (GPP) to give the corresponding chlorinated analogues of geranyl diphosphate (3-ClGPP) and farnesyl diphosphate (3-ClFPP), respectively. No products were detected in incubations of 3-ClIPP with 3-ClDMAPP. Incubation of IPP with 3-ClDMAPP gave 11-ClFPP as the sole product. Values of KM 3-ClIPP (with DMAPP) and KM 3-ClDMAPP (with IPP) were similar to those for IPP and DMAPP; however, values of κcat for both analogues were substantially lower. These results are consistent with a dissociative electrophilic alkylation mechanism where the rate-limiting step changes from heterolytic cleavage of the carbon-oxygen bond in the allylic substrate to alkylation of the double bond of the homoallylic substrate. 2011 American Chemical Society.

11-Substituted-desA-pregnanes and derivatives thereof

This invention is directed to 11-substituted-desA-pregnanes and derivatives thereof which are useful as intermediates in the production of 9β,10α-known steroids of the pregnane series. These latter compounds can be utilized as progestational and salt-retaining agents.