cas 10265-92-6, Methamidophos | Articles data

Articles about 10265-92-6Total 9 be found

Synthesis and characterization of O,S-dimethylphosphoramidothioate and N-acetyl O,S-dimethylphosphoramidothioate
O,S-Dimethylphosphoramidothioate (methamidophos) and N-acetyl O,S-dimethylphos- phoramidothioate (acephate) were synthesized by new methods to investigate the structure-activity study of acetyl cholinesterase (AChE) inhibition through the parameters of logP,δ 31P, and IC 50. After their characterization by NMR (31P, 31P{1H}, 13C, and 1H), IR, and mass spectroscopy, logP and δ31P (31P chemical shift in NMR) were used to evaluate lipophilicity and electronical properties. The logP values for methamidophos and acephate were experimentally determined by the GC-shake-flask method, and the ability of the compounds to inhibit human AChE was evaluated by a modified Ellman's assay. Supplemental materials are available for this article. Go to the publisher's online edition of Phosphorus, Sulfur, and Silicon and the Related Elements to view the free supplemental file.
Ghadimi,Mousavi,Rahnama,Rahimi
p. 347 - 354
(2010)
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PROCESS FOR PREPARATION OF THIOPHOSPHORYL CHLORIDE AND ACEPHATE
The present invention discloses an improved process for preparation of acephate and intermediates thereof. More particularly, the present invention relates to a process for preparation of thiophosphoryl chloride useful for commercial production of pesticides and pharmaceutically active compounds.
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Page/Page column 24

(2021/04/23)

Synthetic method for improving yield of methamidophos intermediate
The invention discloses a synthetic method for improving the yield of a methamidophos intermediate, and belongs to the technical field of fine chemical production. The method comprises the following steps: reacting O,O-dimethyl phosphoramidothioate with a catalyst and dimethyl sulfate at 25-60 DEG C to obtain methamidophos; wherein a solvent is halogenated alkane, and the catalyst comprises one ofmethyl iodide, methyl methanesulfonate, methyl trifluoromethanesulfonate, trimethylsilyl trifluoromethanesulfonate or isopropyl titanate. The method has the advantages that the process is simple, thereaction time is short, the obtained reaction yield is 90% or above, and the target product purity is high.
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Paragraph 0019-0036

(2020/06/24)

Synthesis, spectroscopic characterization and structure-activity relationship of some phosphoramidothioate pesticides
In this work, some phosphoramidothioates (PATs) with the general formula of (CH3O)2P(S)X and (CH3O)(CH3S)P(O)X, where, X = NH2 (1 & 6), NH(CH3) (2 & 7), N(CH3)2 (3 & 8), N(Et)2 (4 & 9), (CH3CH2O)2P(S)NH(CH3) (5) and (CH3CH2O)(CH3CH2S)P(O)NH(CH 3) (10), were synthesized and characterized by 31P, 31P{1H}, 13C and 1H NMR spectroscopy. The ability of the compounds to inhibit AChE was predicted by PASS software (version 1.193). They were also experimentally evaluated by a modified Ellman's assay. The structure-activity relationship (SAR) between IC50 and some physico-chemical properties such as lipophilicity (logP), electronic and steric effects of the compounds was studied. The logP values were experimentally determined by the shake-flask (gas chromatography) method. Inhibitory potency for the compounds 1-10 was 1 (3.38 mM) > 2 (3.97 mM) > 3 (4.75 mM) > 4 (6.00 mM) > 5 (5.51 mM) > 6 (0.07 mM) > 7 (0.23 mM) > 8 (0.39 mM) > and 9 (0.55 mM) > 10 (0.51 mM), respectively. IC50 and logP parameters of the P=O moiety were more than the P=S moiety in PAT analogues.
Ghadimi,Asad-Samani,Ebrahimi-Valmoozi
scheme or table
p. 717 - 726
(2012/07/14)

Mechanisms of composition change and toxic potentiation of chloramidophos emulsifiable concentrate during storage
Storage instability is one of the serious problems that greatly restrict pesticide use. Routine checks on the composition and toxicity of 30% emulsifiable concentrates (EC) of chloramidophos (CP) during storage indicated that 78.6% of the active ingredien
Zhou, Shanshan,Zhang, Datong,Yang, Huayun,Zhang, Ying,Liu, Weiping
experimental part
p. 930 - 937
(2010/04/24)

Concentrates of organophosphorous insecticides
A low volatile organic compound co-solvent system is disclosed for preparing emulsion concentrates of low melting organophosphorous insecticides wherein the bioefficacy of the insecticide active is significantly enhanced. The co-solvent system comprises a water-soluble ethoxylated fatty acid/rosin acid-nonionic surfactant composition.
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(2008/06/13)

Nitro- and cyanoguanidines as selective preemergence herbicides and plant defoliants
There are provided novel nitroguanidine and cyanoguanidine compounds. A method of dessicating and defoliating plants by applying to the foliage thereof certain nitroguanidine or cyanoguanidine compounds and a method for the selective preemergence control of undesirable broadleaf weeds and grasses in the presence of graminaceous crops are disclosed.
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(2008/06/13)

Zu einigen Problemen der Isomerisierung von O,O-Dimethylthiophosphorsaeureesteramiden
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Timm, K.,Treichler, W.,Haberland, D.
p. 310
(2007/10/02)

Condensation products
Formamidine compounds of the formula EQU1 or WHEREIN R1 represents a substituted or unsubstituted phenyl radical, R2 represents hydroogen, alkyl, alkenyl or alkinyl and R3 represents acyl their manufacture and their use in pest control.
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(2008/06/13)