13882-12-7Relevant articles and documents
SCAVENGING OF RADICALS FROM THE GAS PHASE BY FREEZING WITH DIMETHYL DISULFIDE: 1. TEST OF THE METHOD FOR LIGHT RADICALS.
Schottler,Homann
, p. 688 - 694 (1987)
H and O atoms and methyl radicals produced in microwave discharges of H//2/He, O//2/He and CH//4/He mixtures, respectively, were scavenged by supersonic nozzle probing with subsequent freezing and reaction with dimethyl disulfide on a liquid nitrogen cooled wall. The main reaction products for the three kinds of radicals were CH//3SH, CH//3S(O)SCH//3 and CH//3SCH//3, respectively. The scavenging efficiencies for the different radicals were determined and measured as a function of the gas phase radical concentration, the flow of scavenger molecules, the pressure in the vacuum chamber, and the conditions of the discharge and the flow through the sampling nozzle. It is concluded that this method is suitable for light radicals with reservations in the case of H atoms and can probably be used with still better success for heavier radicals.
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Bass,S.W.,Evans,S.A.
, p. 710 (1980)
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Synthesis of a Cyclic 3-Methylsulfonyl Enol Ether
Bennua-Skalmowski, Baerbel,Vorbrueggen, Helmut
, p. 2677 - 2679 (2015)
Electrophilic introduction of a methylmercapto group into dihydropyran gives 3-methylmercaptodihydropyran, which is readily oxidized to 3-methylsulfonyldihydropyran.
Photooxidations of Sulfenic Acid Derivatives 2. A Remarkable Solvent Effect on the Reactions of Singlet Oxygen with Disulfides.
Clennan, Edward L.,Wang, Dongyi,Zhang, Houwen,Clifton, Christine H.
, p. 4723 - 4726 (1994)
Photooxidations of a series of 9 disulfides reveal that the thiosulfinate/thiosulfonate product ratios can be dramatically influenced by the nature of the solvent.The unique ability of methanol to influence this ratio is attributed to nucleophilic addition to a thiopersulfoxide intermediate.
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Moore,T.L.,O'Connor,D.E.
, p. 3587 - 3592 (1966)
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Murray,Jindal
, p. 3516,3519 (1972)
A tissue homogenate method to prepare gram-scale allium thiosulfinates and their disulfide conjugates with cysteine and glutathione
Zhang, Guodong,Parkin, Kirk L.
, p. 3030 - 3038 (2013/08/25)
The health benefits of Allium vegetables are widely attributed to the enzyme-derived organosulfur compounds called thiosulfinates (TS). However, the lack of a suitable method to prepare TS in good yields has hampered the evaluation of their biological activities. This paper describe a simple enzymatic method using Allium tissue homogenates as a reaction system to prepare gram-scale TS, including those enriched in 1-propenyl groups, which are particularly difficult to obtain. This method is simple, easy to scale up, and requires no column purification step, making it suitable for practical large-scale production of Allium TS. The prepared TS were further utilized to prepare the disulfide conjugates with cysteine and glutathione (CySSR and GSSR, R = methyl, ethyl, propyl, 1-propenyl, and allyl), which are the presumptive metabolites of TS. Among all of the Allium CySSR and GSSR conjugates, the newly prepared glutathione conjugate with 1-propenyl TS, GSSPe, showed the most potent effect to induce quinone reductase (QR, a representative phase II enzyme) in murine hepatoma cells (Hepa 1c1c7) and inhibit nitric oxide (NO) production in lipopolysaccharide (LPS)-stimulated macrophage cells (RAW 264.7).