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(2R,3S,5R)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-5-(2-ISOBUTYRAMIDO-6-(4-NITROPHENETHOXY)-9H-PURIN-9-YL)TETRAHYDROFURAN-3-YL 2-CYANOETHYL DIISOPROPYLPHOSPHORAMIDITE is a complex organic molecule characterized by its tetrahydrofuran and cyanoethyl groups, as well as a purine base and nitrophenyl moiety. This versatile compound is utilized in the synthesis of nucleoside analogs and other bioactive compounds, making it a valuable building block in medicinal chemistry and drug development.

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  • (2R,3S,5R)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-5-(2-ISOBUTYRamido-6-(4-NITROPHENETHOXY)-9H-PURIN-9-YL)TETRAHYDROFURAN-3-YL 2-CYANOETHYL DIISOPROPYLPHOSPHORAMIDITE

    Cas No: 102691-37-2

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  • (2R,3S,5R)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-5-(2-ISOBUTYRAMIDO-6-(4-NITROPHENETHOXY)-9H-PURIN-9-YL)TETRAHYDROFURAN-3-YL 2-CYANOETHYL DIISOPROPYLPHOSPHORAMIDITE

    Cas No: 102691-37-2

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  • 102691-37-2 Structure
  • Basic information

    1. Product Name: (2R,3S,5R)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-5-(2-ISOBUTYRAMIDO-6-(4-NITROPHENETHOXY)-9H-PURIN-9-YL)TETRAHYDROFURAN-3-YL 2-CYANOETHYL DIISOPROPYLPHOSPHORAMIDITE
    2. Synonyms: (2R,3S,5R)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-5-(2-ISOBUTYRAMIDO-6-(4-NITROPHENETHOXY)-9H-PURIN-9-YL)TETRAHYDROFURAN-3-YL 2-CYANOETHYL DIISOPROPYLPHOSPHORAMIDITE
    3. CAS NO:102691-37-2
    4. Molecular Formula: C52H61N8O10P
    5. Molecular Weight: 989.06
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 102691-37-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (2R,3S,5R)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-5-(2-ISOBUTYRAMIDO-6-(4-NITROPHENETHOXY)-9H-PURIN-9-YL)TETRAHYDROFURAN-3-YL 2-CYANOETHYL DIISOPROPYLPHOSPHORAMIDITE(CAS DataBase Reference)
    10. NIST Chemistry Reference: (2R,3S,5R)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-5-(2-ISOBUTYRAMIDO-6-(4-NITROPHENETHOXY)-9H-PURIN-9-YL)TETRAHYDROFURAN-3-YL 2-CYANOETHYL DIISOPROPYLPHOSPHORAMIDITE(102691-37-2)
    11. EPA Substance Registry System: (2R,3S,5R)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-5-(2-ISOBUTYRAMIDO-6-(4-NITROPHENETHOXY)-9H-PURIN-9-YL)TETRAHYDROFURAN-3-YL 2-CYANOETHYL DIISOPROPYLPHOSPHORAMIDITE(102691-37-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 102691-37-2(Hazardous Substances Data)

102691-37-2 Usage

Uses

Used in Medicinal Chemistry:
(2R,3S,5R)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-5-(2-ISOBUTYRAMIDO-6-(4-NITROPHENETHOXY)-9H-PURIN-9-YL)TETRAHYDROFURAN-3-YL 2-CYANOETHYL DIISOPROPYLPHOSPHORAMIDITE is used as a key intermediate in the synthesis of nucleoside analogs for its ability to introduce specific functional groups and structural elements into target molecules.
Used in Drug Development:
In the pharmaceutical industry, this compound serves as a crucial building block for the development of new drugs, particularly those targeting various diseases and conditions. Its unique structure allows for the creation of bioactive molecules with potential therapeutic applications.

Check Digit Verification of cas no

The CAS Registry Mumber 102691-37-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,2,6,9 and 1 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 102691-37:
(8*1)+(7*0)+(6*2)+(5*6)+(4*9)+(3*1)+(2*3)+(1*7)=102
102 % 10 = 2
So 102691-37-2 is a valid CAS Registry Number.

102691-37-2Downstream Products

102691-37-2Relevant articles and documents

New 2-(4-nitrophenyl)ethyl(Npe)- and 2-(4- nitrophenyl)ethoxycarbonyl(Npeoc)protected 2'-deoxyribonucleosides and their 3'-phosphoramidites - Versatile building blocks for oligonucleotide synthesis

Lang, Holger,Gottlieb, Margarete,Schwarz, Michael,Farkas, Silke,Schulz, Bernd S.,Himmelsbach, Frank,Charubala, Ramamurthy,Pfleiderer, Wolfgang

, p. 2172 - 2185 (2007/10/03)

A series of new base-protected and 5'-O-(4-monomethoxytrityl)- or 5'-O- (4,4'-dimethoxytrityl)-substituted 3'-(2-cyanoethyl diisopropylphosphoramidites) and 3'-[2-(4-nitrophenyl)ethyl diisopropylphosphoramidites] 52-66 and 67-82, respectively, are prepare

POLYMER-SUPPORTED SYNTHESIS OF DEOXYOLIGONUCLEOTIDES USING IN SITU PREPARED DEOXYNUCLEOSIDE 2-CYANOETHYL PHOSPHORAMIDITES

Nielsen, J.,Marugg, J. E.,Taagaard, M.,Boom, J. H. van,Dahl, O.

, p. 33 - 34 (2007/10/02)

The easily acessibile reagent 2-cyanoethyl-bis(diisopropylamino)phosphoramidite is shown to be suitable for the in-situ, 1H-tetrazole catalysed, preparation of d-nucleoside-3'-phosphoramidites.THe latter compounds could be applied successfuly as building blocks in a solid-phase DNA synthesis using an automated DNA synthesizer.

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