102691-37-2Relevant articles and documents
New 2-(4-nitrophenyl)ethyl(Npe)- and 2-(4- nitrophenyl)ethoxycarbonyl(Npeoc)protected 2'-deoxyribonucleosides and their 3'-phosphoramidites - Versatile building blocks for oligonucleotide synthesis
Lang, Holger,Gottlieb, Margarete,Schwarz, Michael,Farkas, Silke,Schulz, Bernd S.,Himmelsbach, Frank,Charubala, Ramamurthy,Pfleiderer, Wolfgang
, p. 2172 - 2185 (2007/10/03)
A series of new base-protected and 5'-O-(4-monomethoxytrityl)- or 5'-O- (4,4'-dimethoxytrityl)-substituted 3'-(2-cyanoethyl diisopropylphosphoramidites) and 3'-[2-(4-nitrophenyl)ethyl diisopropylphosphoramidites] 52-66 and 67-82, respectively, are prepare
POLYMER-SUPPORTED SYNTHESIS OF DEOXYOLIGONUCLEOTIDES USING IN SITU PREPARED DEOXYNUCLEOSIDE 2-CYANOETHYL PHOSPHORAMIDITES
Nielsen, J.,Marugg, J. E.,Taagaard, M.,Boom, J. H. van,Dahl, O.
, p. 33 - 34 (2007/10/02)
The easily acessibile reagent 2-cyanoethyl-bis(diisopropylamino)phosphoramidite is shown to be suitable for the in-situ, 1H-tetrazole catalysed, preparation of d-nucleoside-3'-phosphoramidites.THe latter compounds could be applied successfuly as building blocks in a solid-phase DNA synthesis using an automated DNA synthesizer.