103440-53-5Relevant articles and documents
SUBSTITUTED OXOISOINDOLINE COMPOUNDS FOR THE TREATMENT OF CANCER
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Page/Page column 140, (2021/10/02)
Disclosed are compounds of Formula (I) or a salt thereof, wherein Ring A is a carbon-linked ring; and Ring A, R1, and n are defined herein. Also disclosed are methods of using such compounds to inhibit Helios protein, and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.
INHIBITORS OF HEPATITIS C VIRUS POLYMERASE
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Paragraph 560; 561, (2016/10/11)
The present invention provides, among other things, compounds represented by the general Formula I: (I) and pharmaceutically acceptable salts thereof, wherein L and A (and further substituents) are as defined in classes and subclasses herein and compositions (e.g., pharmaceutical compositions) comprising such compounds, which compounds are useful as inhibitors of hepatitis C virus polymerase, and thus are useful, for example, as medicaments for the treatment of HCV infection.
[1, 2, 4] TRIAZOLO [1, 5-A] PYRIDINES AS JAK INHIBITORS
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Page/Page column 80; 81, (2010/04/03)
Novel [1,2,4]triazolo[1,5-a]pyridine compounds are disclosed that have a Formula represented by the following: (I). The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, joint disease, inflammation, and others.
Doxepin analogs and methods of use thereof
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Page/Page column 51, (2008/06/13)
The invention relates to novel antihistamines and methods of modulating sleep by administering a doxepin analog or a pharmaceutically effective salt thereof.
Aryl and heteroaryl (phosphinylmethyl)phosphonate squalene synthetase inhibitors and method
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, (2008/06/13)
Phosphonic acid squalene synthetase inhibitors are provided which are effective in lowering serum cholesterol and have the formula STR1 wherein m is 0 to 3, n is 1 to 5, Y1 and Y2 are H or halogen, R2, R3 and R4 are H, metal ion, C1 to C8 alkyl, C3 to C12 alkenyl, or prodrug ester, and R1 is a substituted or unsubstituted heteroaryl group or a substituted phenyl group.