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3-Amino-5-fluoro-1H-pyrazole-4-carbonitrile, a pyrazole derivative with the molecular formula C4H3FN4, is a chemical compound featuring an amino group and a fluorine atom attached to its five-membered ring. It is known for its unique structure and properties, making it a promising candidate for various applications in the pharmaceutical and agrochemical industries, as well as in research and development.

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  • 1034667-22-5 Structure
  • Basic information

    1. Product Name: 3-Amino-5-fluoro-1H-pyraz...
    2. Synonyms: 3-Amino-5-fluoro-1H-pyraz...;3-AMino-5-fluoro-1H-pyrazolo[3,4-b]pyridine;5-Fluoro-1H-pyrazolo[3,4-b]pyridin-3-ylaMine;5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine
    3. CAS NO:1034667-22-5
    4. Molecular Formula: C6H5FN4
    5. Molecular Weight: 152.1291032
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1034667-22-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 408.7±40.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.604±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
    8. Solubility: N/A
    9. PKA: 9.71±0.40(Predicted)
    10. CAS DataBase Reference: 3-Amino-5-fluoro-1H-pyraz...(CAS DataBase Reference)
    11. NIST Chemistry Reference: 3-Amino-5-fluoro-1H-pyraz...(1034667-22-5)
    12. EPA Substance Registry System: 3-Amino-5-fluoro-1H-pyraz...(1034667-22-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1034667-22-5(Hazardous Substances Data)

1034667-22-5 Usage

Uses

Used in Pharmaceutical Industry:
3-Amino-5-fluoro-1H-pyrazole-4-carbonitrile is used as an intermediate in the synthesis of pharmaceuticals for its potential role in the development of new drugs. Its unique structure allows for the creation of various organic compounds with therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 3-Amino-5-fluoro-1H-pyrazole-4-carbonitrile serves as an intermediate in the synthesis of agrochemicals, contributing to the development of effective pesticides and other agricultural products.
Used in Research and Development:
3-Amino-5-fluoro-1H-pyrazole-4-carbonitrile is utilized as a building block in research and development for the production of various organic compounds. Its versatile chemical properties make it an essential component in the creation of novel molecules with potential applications in different fields.
Used in Medicinal Chemistry:
With its potential applications in the field of medicinal chemistry, 3-Amino-5-fluoro-1H-pyrazole-4-carbonitrile is employed for the development of new drugs. Its unique structure and properties enable the design and synthesis of innovative pharmaceutical compounds with improved therapeutic effects.

Check Digit Verification of cas no

The CAS Registry Mumber 1034667-22-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,4,6,6 and 7 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1034667-22:
(9*1)+(8*0)+(7*3)+(6*4)+(5*6)+(4*6)+(3*7)+(2*2)+(1*2)=135
135 % 10 = 5
So 1034667-22-5 is a valid CAS Registry Number.

1034667-22-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-fluoro-2H-pyrazolo[3,4-b]pyridin-3-amine

1.2 Other means of identification

Product number -
Other names 5-fluoro-1H-pyrazolo[3,4-b]pyridine-3-amine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1034667-22-5 SDS

1034667-22-5Downstream Products

1034667-22-5Relevant articles and documents

AMINO-QUINOLINES AS KINASE INHIBITORS

-

, (2018/06/22)

Disclosed are compounds having the formula:wherein R 1 , R 2 , R 3 and Z are as defined herein, and methods of making and using the same.

Pyrazolopyridine compound and use thereof

-

, (2018/11/03)

The present invention relates to a pyrazolopyridine compound and use thereof, and further relates to a pharmaceutical composition comprising the pyrazolopyridine compound. The pyrazolopyridine compound or the pharmaceutical composition can be used as a so

Influenza virus replication inhibitor and application thereof

-

Paragraph 0633; 0635; 0636, (2018/07/30)

The invention relates to an influenza virus replication inhibitor and application thereof, and particularly relates to a compound serving as an influenza virus replication inhibitor, a preparation method thereof, a pharmaceutical composition containing the compound, and application of the compound and the pharmaceutical composition to influenza treatment.

INHIBITORS OF INFLUENZA VIRUS REPLICATION AND USES THEREOF

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Paragraph 00294, (2018/07/31)

Provided herein is inhibitors of influenza virus replication and uses thereof. Specifically, provided herein a novel class of compounds as inhibitors of influenza virus replication, preparation methods thereof, pharmaceutical compositions containing these compounds, and uses of these compounds and pharmaceutical compositions thereof in the treatment of influenza.

BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA

-

, (2017/12/27)

The present invention relates to a compound having the formula (I), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, prodrug, codrug, cocrystal, tautomer, racemate, enantiomer, or diastereomer or mixture thereof, which is useful in treating, ameloriating or preventing influenza.

PYRIMIDINE AND PYRIDINE DERIVATIVES AND USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA THEREOF

-

, (2017/12/28)

Provided herein is a compound of formula (I), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, prodrug, codrug, cocrystal, tautomer, racemate, enantiomer, or diastereomer or mixture thereof, which is useful in treating, ameliorating or preventing influenza.

AMINO-QUINOLINES AS KINASE INHIBITORS

-

, (2018/05/15)

Disclosed are compounds having the formula: wherein R1, R2, R3 and Z are as defined herein, and methods of making and using the same.

AMINO-QUINOLINES AS KINASE INHIBITORS

-

, (2016/10/31)

Disclosed are compounds having the formula: wherein R1, R2, R3 and Z are as defined herein, and methods of making and using the same.

HETEROARYL-SUBSTITUTED PYRAZOLOPYRIDINES AND USE THEREOF AS SOLUBLE GUANYLATE CYCLASE STIMULATORS

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, (2014/08/19)

The present application relates to novel heteroaryl-substituted pyrazolopyridines, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for t

FLUOROALKYL-SUBSTITUTED PYRAZOLOPYRIDINES AND USE THEREOF

-

, (2014/04/18)

The present application relates to novel fluoroalkyl-substituted pyrazolopyridines, to processes for their preparation, to their use, alone or in combinations, for the treatment and/or prophylaxis of diseases and to their use for production of medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prophylaxis of cardiovascular disorders.

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