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2-Chloro-5-fluoronicotinamide, also known as 2-chloro-5-fluoropyridine-3-carboxamide, is an organic compound with the CAS number 884495-63-0. It has a molecular formula of C6H4ClFN2O and a molecular weight of 176.56 g/mol. 2-chloro-5-fluoronicotinaMide is a member of the halopyridine carboxylic acids and derivatives class, which are derivatives of pyridine carboxylic acid with one or more halogen atoms on the ring. The chemical's properties and applications are largely due to the presence of reactive halogen groups.

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  • 75302-64-6 Structure
  • Basic information

    1. Product Name: 2-chloro-5-fluoronicotinaMide
    2. Synonyms: 2-chloro-5-fluoronicotinaMide
    3. CAS NO:75302-64-6
    4. Molecular Formula: C6H4ClFN2O
    5. Molecular Weight: 175
    6. EINECS: -0
    7. Product Categories: N/A
    8. Mol File: 75302-64-6.mol
  • Chemical Properties

    1. Melting Point: 137-139 °C
    2. Boiling Point: 247.6±40.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.485±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. PKA: 13.65±0.50(Predicted)
    10. CAS DataBase Reference: 2-chloro-5-fluoronicotinaMide(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-chloro-5-fluoronicotinaMide(75302-64-6)
    12. EPA Substance Registry System: 2-chloro-5-fluoronicotinaMide(75302-64-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 75302-64-6(Hazardous Substances Data)

75302-64-6 Usage

Uses

Used in Pharmaceutical Industry:
2-Chloro-5-fluoronicotinamide is used as a chemical intermediate for the synthesis of various pharmaceutical substances. Its presence of reactive halogen groups makes it a valuable component in the development of new drugs and medications.
Used in Organic Chemistry Research:
2-Chloro-5-fluoronicotinamide is used as a research compound in the field of organic chemistry. Its unique structure and properties allow scientists to explore new reactions and syntheses, potentially leading to the discovery of novel compounds with various applications.

Check Digit Verification of cas no

The CAS Registry Mumber 75302-64-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,3,0 and 2 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 75302-64:
(7*7)+(6*5)+(5*3)+(4*0)+(3*2)+(2*6)+(1*4)=116
116 % 10 = 6
So 75302-64-6 is a valid CAS Registry Number.

75302-64-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-chloro-5-fluoropyridine-3-carboxamide

1.2 Other means of identification

Product number -
Other names 3-Pyridinecarboxamide,2-chloro-5-fluoro

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:75302-64-6 SDS

75302-64-6Relevant articles and documents

Pyrazolopyridine compound and use thereof

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, (2018/11/03)

The present invention relates to a pyrazolopyridine compound and use thereof, and further relates to a pharmaceutical composition comprising the pyrazolopyridine compound. The pyrazolopyridine compound or the pharmaceutical composition can be used as a so

AMINO-QUINOLINES AS KINASE INHIBITORS

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Page/Page column 67, (2018/06/22)

Disclosed are compounds having the formula:wherein R 1 , R 2 , R 3 and Z are as defined herein, and methods of making and using the same.

BICYCLIC PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA

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, (2017/12/27)

The present invention relates to a compound having the formula (I), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, prodrug, codrug, cocrystal, tautomer, racemate, enantiomer, or diastereomer or mixture thereof, which is useful in treating, ameloriating or preventing influenza.

PYRIMIDINE AND PYRIDINE DERIVATIVES AND USE IN TREATMENT, AMELIORATION OR PREVENTION OF INFLUENZA THEREOF

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, (2017/12/28)

Provided herein is a compound of formula (I), optionally in the form of a pharmaceutically acceptable salt, solvate, polymorph, prodrug, codrug, cocrystal, tautomer, racemate, enantiomer, or diastereomer or mixture thereof, which is useful in treating, ameliorating or preventing influenza.

AMINO-QUINOLINES AS KINASE INHIBITORS

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Page/Page column 77; 78, (2018/05/15)

Disclosed are compounds having the formula: wherein R1, R2, R3 and Z are as defined herein, and methods of making and using the same.

AMINO-QUINOLINES AS KINASE INHIBITORS

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Paragraph 0134, (2016/10/31)

Disclosed are compounds having the formula: wherein R1, R2, R3 and Z are as defined herein, and methods of making and using the same.

AMINO QUINAZOLINES AS KINASE INHIBITORS

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Paragraph 0164; 0165, (2016/12/12)

Disclosed are compounds having the formula (Formula I)): wherein R1, R2, R3 and Z are as defined herein, and methods of making and using the same.

ANTIBACTERIAL COMPOUNDS HAVING BROAD SPECTRUM OF ACTIVITY

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Page/Page column 105, (2016/07/05)

The present invention relates to novel antibacterial compounds, pharmaceutical compositions containing them and their use as antimicrobials.

FLUOROALKYL-SUBSTITUTED PYRAZOLOPYRIDINES AND USE THEREOF

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Page/Page column, (2014/04/18)

The present application relates to novel fluoroalkyl-substituted pyrazolopyridines, to processes for their preparation, to their use, alone or in combinations, for the treatment and/or prophylaxis of diseases and to their use for production of medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prophylaxis of cardiovascular disorders.

BICYCLIC AZA HETEROCYCLES, AND USE THEREOF

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, (2014/06/11)

The present application relates to novel bicyclic azaheterocycles, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of cardiovascular disorders.

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