Nitrosoimidazoles: Highly Bactericidal Analogues of 5-Nitroimidazole Drugs
It is believed that metronidazole and related 5-nitroimidazoles are activated by reduction of the nitro group and that the active species has a nitrogen functionality of intermediate oxidation state.However, the preparation and isolation of the active for
Ehlhardt, William J.,Beaulieu, Bernard B.,Goldman, Peter