Journal of Medicinal Chemistry p. 323 - 329 (1988)
Update date:2022-08-04
Topics:
Ehlhardt, William J.
Beaulieu, Bernard B.
Goldman, Peter
It is believed that metronidazole and related 5-nitroimidazoles are activated by reduction of the nitro group and that the active species has a nitrogen functionality of intermediate oxidation state.However, the preparation and isolation of the active for
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