104311-39-9Relevant articles and documents
Verification of the necessity of the tolyl group of PF-543 for sphingosine kinase 1 inhibitory activity
Baek, Dong Jae,Ki, Sung Hwan,Kim, Sang-Bum,Kim, Sanghee,Kim, Su Bin,Kwon, Yongseok,Lee, Joo-Youn,Lee, Taeho,Moon, Hong Seop,Oh, Yoon Sin,Park, Eun-Young,Park, Jeong-Eun
, (2020)
PF-543, the most potent sphingosine kinase (SK) inhibitor, does not demonstrate effective anticancer activity in some cancer cells, unlike other known SK1 inhibitors. PF-543 has a non-lipid structure with a unique toluene backbone; however, the importance
Biomimetic preparation of the racemic modifications of the stilbenolignan aiphanol and three congeners
Chand, Satish,Banwell, Martin G.
, p. 243 - 250 (2008/02/11)
A chromatographically separable mixture of the racemic modification, (±)-1, of the stilbenolignan (-)-aiphanol and congeners (±)-2-4 has been generated by a silver(I)-mediated and potentially biomimetic oxidative coupling of piceatannol (5) with sinapic a
SYNTHESE DE CETONES SPIRANNIQUES TRICYCLIQUES DERIVEES DE PRODUITS NATURELS
Berrier, Christian,Jacquesy, Jean-Claude,Renoux, Alain
, p. 212 - 218 (2007/10/02)
In SbF5-HF compound 10a is unreactive whereas esters 10b and 10c cyclize to enones 18 (b or c) and 19 (b or c).Protonation of the esters groups prevents the corresponding aromatic ring protonation and deactivation which is observed with phenol 10a.Spiroke
SYNTHESIS OF CONDENSED TANNINS. PART 18. STILBENES AS POTENT NUCLEOPHILES IN REGIO- AND STEREO-SPECIFIC CONDENSATIONS: NOVEL GUIBOURTINIDOL-STILBENES FROM GUIBOURTIA COLEOSPERMA
Steynberg, Jan P.,Ferreira, Daneel,Roux, David G.
, p. 1705 - 1712 (2007/10/02)
(E)-3,3',4,5'-Tetrahydroxy- and 3',4,5'-trihydroxy-stilbenes function as strong nucleophiles in regio- and stereo-specific condensations with carbenium ions generated from 2,3-trans- and 2,3-cis-flavan-3,4,4',7-tetraols (leucoguibourtinidins) to generate