- PYRIDINECARBOXAMIDES DERIVATIVES, PREPARATION PROCESS AND PHARMACEUTICAL USE THEREOF
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The present invention relates to pyridinecarboxamides derivatives, preparation processes and pharmaceutical use thereof. Specifically, the present invention relates to pyridinecarboxamides derivatives of general formula (I) and the pharmaceutical composition, as well as their use as a therapeutic agent, especially these compounds are inhibitors of ROMK and are therefore useful in the treatment and/or prevention of hypertension and heart failure, wherein each substitute of general formula (I) is defined as the specification.
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(2017/01/02)
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