108857-24-5

Basic information

• Product Name: 2-AMINO-5-IODO-3-METHYLBENZOIC ACID
• Synonyms: 2-AMINO-5-IODO-3-METHYLBENZOIC ACID;2-Amino-5-iodo-3-methylbenzenecarboxylic acid
• CAS NO: 108857-24-5
• Molecular Formula: C₈H₈INO₂
• Molecular Weight: 277.05909
• Mol File: 108857-24-5.mol

Chemical Properties

• Melting Point: 235-240°
• Appearance: /
• Storage Temp.: 2-8°C
• Solubility: DMF
• CAS DataBase Reference: 2-AMINO-5-IODO-3-METHYLBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-5-IODO-3-METHYLBENZOIC ACID(108857-24-5)
• EPA Substance Registry System: 2-AMINO-5-IODO-3-METHYLBENZOIC ACID(108857-24-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 108857-24-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Amino-5-Iodo-3-Methylbenzoic Acid is used as an intermediate in the synthesis of highly potent and selective activators of insect ryanodine receptors. These activators are crucial for the development of novel insecticides, as they target specific receptors in insects, leading to more effective and environmentally friendly pest control solutions.
Used in Chemical Synthesis:
2-Amino-5-Iodo-3-Methylbenzoic Acid can also be utilized in the synthesis of other organic compounds, such as dyes, pigments, and pharmaceuticals. Its versatile structure allows for further functionalization and modification, making it a valuable building block in organic chemistry.

Upstream product

• 7647-01-0 hydrogenchloride 
• 4389-45-1 3-methylantranilic acid 
• 7790-99-0 Iodine monochloride 

Downstream Products

• 908005-99-2 2-amino-5-iodo-3-methyl-benzoic acid ethyl ester 
• 871239-18-8 2-amino-5-cyano-3-methyl-benzoic acid 
• 913194-96-4 6-iodo-8-methyl-1H-benzo[d][1,3]oxazine-2,4-dione 
• 1096481-48-9 methyl 2-amino-5-iodo-3-methyl-benzoate 
• 1032667-27-8 2-amino-5-cyano-N-ethyl-3-methylbenzamide 
• 890707-29-6 2-amino-3-methyl-5-cyanobenzoyl-N-methylamine 

Relevant articles and documents

Development of a monoclonal antibody-based ELISA for the detection of the novel insecticide cyantraniliprole

Cyantraniliprole is the newest anthranilic diamide insecticide acting on ryanodine receptors with higher efficacy, and broader spectrum than chlorantraniliprole in pest control. To study the effects of its residues on the environment and food samples, an

Design, Synthesis, and Biological Screening of Novel Anthranilic Diamides

Three series of new anthranilic diamide derivatives containing sulfide, N-cyanomethylsulfilimine, and N-cyanomethylsulfoximine groups were designed and synthesized by combining the active substructures of anthranilic diamides and sulfoxaflor. The structures of all newly synthesized compounds were confirmed by IR and 1H/13C-NMR, and some of them were confirmed by elemental analysis or HRMS too. The synthesized compounds were screened for their insecticidal and fungicidal activities. Bioasssay results indicated that some of the synthesized compounds possessed certain degrees of insecticidal activity against Mythimna separata. However, some compounds exhibited good fungicidal activity against Sclerotinia sclerotiorum.

INHIBITORS OF ENCEPHALITIC ALPHAVIRUSES

Compounds of Formula I and Formula II: pharmaceutical compositions containing them, and use of the compounds as active ingredients to treat infection with alphavirus.

A kind of including sulphone (sulfur) imine O-formyl amino benzamide derivatives and its preparation and use

The invention provides o-formylamino benzamide derivatives containing sulfone(sulfur)imine and a preparation method and used thereof. The invention relates to bisamide derivatives containing pyrazole formamide, wherein the general chemical structural formula of the bisamide derivatives is shown as I. The invention discloses the general structural formula and synthesis methods of the compounds, used of the compounds serving as insecticides, bactericides, plant virus resisting agents and plant activators and processing processes for the compounds in the preparation of the insecticides, the bactericides, the plant virus resisting agents and the plant activators in a manner that the compounds are mixed with agriculturally-acceptable assistants or synergists. The invention further discloses uses of combination of the compounds with the commercial insecticides, bactericides, plant virus resisting agents and plant activators in the prevention and treatment of the diseases, insect pests and viral diseases in agriculture, forestry and horticulture and a preparation method thereof.

Cyan dihalogenation pyrazol amide series compound and preparation method and application thereof

The invention discloses a cyan dihalogenation pyrazol amide series compound and a preparation method and application thereof. The general chemical molecular formula of the compound is CHNOClBrR1R2, wherein R1 represents methyl, Cl or Br; R

O-carboxamido benzamide derivative based on ryanodine receptor, and preparation method and application thereof

The invention provides a series of o-carboxamido benzamide derivatives, and preparation methods and applications thereof. The o-carboxamido benzamide derivatives have the chemical structure general formula represented as the formula I. The invention also discloses: the general formula and the synthetic method of the compounds and an application of the compounds in insecticides, acaricides and bactericides, and a process of preparing the acaricides and bactericides by mixing the compounds with agriculturally acceptable additives or synergists, and also discloses the combination of the compounds with commercial insecticides, acaricides, bactericides, anti-plant-viral agents and plant activators to prevent and treat diseases, pest damage, mite damage and viral diseases in the fields of agriculture, forestry and horticulture.

POLYSUBSTITUTED PYRIDYL PYRAZOLECARBOXAMIDE AND PREPARATION METHOD AND USE THEREOF

The present invention discloses a polysubstituted pyridyl pyrazolecarboxamide and its preparation method and use. The structure of the polysubstituted pyridyl pyrazolecarboxamide of the present invention is shown in the following General Formula I. The po

ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES

The present invention relates to anthranilamide compounds and the stereoisomers, salts, tautomers and N-oxides thereof and to compositions comprising the same. The invention also relates to the use of the anthranilamide compounds or of the compositions co

ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES

The present invention relates to anthranilamide compounds and the stereoisomers, salts, tautomers and N-oxides thereof and to compositions comprising the same. The invention also relates to the use of the anthranilamide compounds or of the compositions co

Nucleophilic ring-opening reaction of benzoxazinones - Access to o-amino-2,2,2-trifluoroacetophenones

Organofluorine compounds are of high interest in modern drug discovery and material sciences. We herein report a new synthetic access to o-amino-2,2,2-trifluoroacetophenones starting from commercially available o-amino benzoic acids, which can easily be converted into the corresponding benzoxazinones. In a second step the trifluoromethylated ketone is formed via addition of Ruppert's reagent following acidic work up.