109-98-8

Basic information

• Product Name: 2-PYRAZOLINE
• Synonyms: 2-PYRAZOLINE;pyrazoline;4,5-dihydro-1H-pyrazole;2-PYRAZOLINE 95+%
• CAS NO: 109-98-8
• Molecular Formula: C₃H₆N₂
• Molecular Weight: 70.09
• EINECS: 203-725-2
• Mol File: 109-98-8.mol

Chemical Properties

• Melting Point: 163-165 °C
• Boiling Point: 144°C
• Flash Point: 40.9°C
• Appearance: /
• Density: 1,02 g/cm3
• Vapor Pressure: 6.54mmHg at 25°C
• Refractive Index: 1.4870 to 1.4920
• PKA: 4.60±0.70(Predicted)
• Merck: 14,7961
• CAS DataBase Reference: 2-PYRAZOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-PYRAZOLINE(109-98-8)
• EPA Substance Registry System: 2-PYRAZOLINE(109-98-8)

Safety Data

• Statements: 10
• Safety Statements: 16
• RIDADR: 1993
• RTECS: KO0710000
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 109-98-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C3H6N2/c1-2-4-5-3-1/h2,5H,1,3H2

Upstream product

• 186581-53-3 diazomethane 
• 74-85-1 ethene 
• 288-13-1 NH-pyrazole 
• 107-02-8 acrolein 
• 4316-74-9 2-methylamino-1-ethanesulphonic acid sodium salt 
• 625-36-5 2-chloropropionyl chloride 
• 49651-51-6 3-benzenesulfonyl-4,5-dihydro-1H-pyrazole 

Downstream Products

• 110182-02-0 4,5-dihydro-pyrazole-1-carbothioic acid anilide 
• 82499-69-2 1-benzenesulfonyl-4,5-dihydro-1H-pyrazole 
• 5920-44-5 1-(2,4-dinitrophenyl)-4,5-dihydro-1H-pyrazole 
• 288-13-1 NH-pyrazole 
• 900188-90-1 1-(4,5-dihydropyrazol-1-yl)phenylmethanone 
• 802982-86-1 4,5-dihydropyrazole-1-carboxylic acid benzyl ester 
• 78158-12-0 1-(3,5-dichlorobenzoyl)-3-(4-methylphenyl)-pyrazoline 
• 35229-00-6 4-methoxy-3,5-diphenypyrazole 
• 1039740-61-8 4-nitrophenyl 4,5-dihydro-1H-pyrazole-1-carboxylate 
• 1337564-61-0 N-[(4,5-dihydro-1H-pyrazol-1-yl)-methylsulfanyl-methylidene]-3-chlorobenzenesulfonamide 

Relevant articles and documents

NOVEL AROMATIC COMPOUND AND POLYARYLENE COPOLYMER HAVING NITROGEN-CONTAINING HETEROCYCLE INCLUDING SULFONIC ACID GROUP IN SIDE CHAIN

Provided is a solid polymer electrolyte having increased heat resistance and high proton conductivity and a proton conductive membrane composed of the electrolyte. Also provided is a copolymer having a sulfonic acid group. The copolymer includes a repeating unit represented by Formula (1): (in the formula, Y denotes at least one kind of structure selected from the group consisting of —CO—, —SO2—, —SO—, —CONH—, —COO—, —(CF2)l— (l is an integer of 1 to 10), and —C(CF3)2—; W denotes at least one kind of structure selected from the group consisting of a direct bond, —CO—, —SO2—, —SO—, —CONH—, —COO—, —(CF2)l— (l is an integer of 1 to 10), —C(CF3)2—, —O—, and —S—; Z denotes a direct bond or at least one kind of structure selected from the group consisting of —(CH2)l—(l is an integer of 1 to 10), —C(CH3)2—, —O—, —S—, —CO—, and —SO2—; R30 denotes a nitrogen-containing aromatic ring having a substituent represented by —SO3H, —O(CH2)hSO3H, or —O(CF2)hSO3H (h is an integer of 1 to 12); p is an integer of 0 to 10; q is an integer of 0 to 10; r is an integer of 1 to 5; and k is an integer of 0 to 4).

Methods and compositions for photo-cross linking photoactive compounds to target tissue

The present invention discloses novel photoactive compounds that may be crosslinked to target substrates. Methods for the preparation and use of the compounds, as well as compositions comprising them, are also disclosed.

Taxane derivatives, the preparation thereof and formulations containing them

The present invention relates to the preparation of taxane derivatives starting from 10-deacetyl-baccatine III, 14-hydroxy-10-deacetyl-baccatine 111, 19-hydroxy-10-deacetyl-baccatine III and their esters at C13, reacting the respective 10-dehydro derivatives with hydrazine, hydroxylamine and derivatives thereof. The novel compounds contain a pyrazoline group involving the C7 and C9 carbons. The C13 esters of these molecules with substituted isoserine chains exert antitumor activity inhibiting cell proliferation of normal and resistant tumor cell lines and inducing apoptosis. These molecules due to their basic character can be administered upon salification in an aqueous medium without requiring the use of toxic surfactants.

Pyrazolines for protecting crop plants against herbicides

Compounds of the formula (I) STR1 where X, n, R1, R2 and R3 are as defined in claim 1 are suitable as antidotes against phytotoxic secondary effects of herbicides in crop plants without adversely affecting the action of the herbicides against harmful plants.

Process of preparation of tetrafluoro 2,3-dihydrobenzofurans

Tetrafluorobenzofurans of the formula STR1 are prepared by contacting, at elevated temperature in an aprotic solvent, an ether of the formula STR2 with a catalytic mixture of metallic cooper and a polydentate or other ligand, wherein R1 is hydrogen, nitro, amino, phthalimido or acetylimido, R2 is at least one of hydrogen, halo, cyano, alkyl, hydroxy, alkoxy, acyl, acyloxy, alkoxycarbonyl, alkoxycarbonylalkyl, phenyl, phenyloxy, trifluoromethyl or dialkylamino. The products are intermediates in the preparation of pyrazoline insecticides.

Photochemistry of Azocyclopropane

trans-Azocyclopropane (1t) has been irradiated in the gas phase at 254 nm and in hydrocarbon solution at several wavelengths.As with most acyclic azoalkanes, the dominant reaction is isomarization to the cis-azoalkane 1c.In the gas phase or with short wavelength light, 1t undergoes competitive C-N homolysis, giving cyclopropyl radicals, and ring fragmentation to ethylene.Triplet-sensitized isomerization of the azo linkage proceeds with unusually high efficiency (Φt->c=0.2), but no experimental support could be found for the notion that cyclopropane ring cleavage leads to azo group isomerization.Since azocyclopropane behaves as a "reluctant azoalkane" that undergoes multiple photoreactions, it is not a particularly useful source of cyclopropyl radicals.

Process for the preparation of pyrazole

Process for the preparation of pyrazole from hydrazine hydrate and acrolein comprising reacting hydrazine hydrate with acrolein in an aqueous-organic medium at a temperature between 20°-80° C. and then oxidizing the 2-pyrazoline formed, of the formula STR1 either directly or after first being isolated, with chlorine or an alkali metal hypochlorite or an alkaline earth metal hypochlorite and water or an aqueous-organic medium at a temperature between 0° and 60° C.

Synthesis and Spectral Studies of Some 3-Arylsulphonyl-2-pyrazolines

The cycloaddition of diazomethane to aryl vinyl sulphones in the presence of triethylamine at 0 deg C gives 3-arylsulphonyl-2-pyrazolines (2).The orientation of addition has been arrived on the basis of IR, PMR and 13C NMR spectral data.The characteristic N-H absorption of 2 and the absence of this in 1-arylsulphonyl- and 1-benzoyl-2-pyrazolines (3 and 4) together with A2B2 pattern observed for 2, 3 and 4 establish the structure of 2.

Bis-triazolyl and bis-pyrazolyl stilbene compounds

The invention relates to stilbene derivatives which are used as optical brightening agents, particularly as anionic brightening agents for polyamide and cellulosic substrates. These stilbene derivatives have the formula I STR1 in which both X's are the same and are CR5 or N, where R5 is hydrogen, C1-4 alkyl or phenyl; both Y's are the same and are each one of the radicals of benzofuran, triazole, pyrazole, dibenzofuran or dibenzothiophene and benzothiophene, and R1 is as defined in the specification.

Pyrazoline compounds

Compounds of the formula STR1 wherein R1, R2 and R3 denote hydrogen, chlorine or methyl, R4 denotes C1 -C4 -alkyl which is optionally substituted by phenyl, hydroxyl or C1 -C4 -alkoxy and X? denotes a colorless anion. A process for their preparation and processes for brightening polyacrylonitrile and wool using compounds of the formula (I).