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109543-76-2

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  • 2-[[2-(4-chlorophenyl)-4-methyl-1,3-oxazol-5-yl]methoxy]-2-methylpropanoic acid

    Cas No: 109543-76-2

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  • 109543-76-2 Structure

  • Basic information

    1. Product Name: Romazarit
    2. Synonyms: Romazarit;2-Methyl-2-[[4-methyl-2-(4-chlorophenyl)oxazol-5-yl]methoxy]propionic acid;Ro-31-3948
    3. CAS NO:109543-76-2
    4. Molecular Formula: C15H16ClNO4
    5. Molecular Weight: 309.747
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 109543-76-2.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 486.8°Cat760mmHg
    3. Flash Point: 248.2°C
    4. Appearance: /
    5. Density: 1.278g/cm3
    6. Vapor Pressure: 2.74E-10mmHg at 25°C
    7. Refractive Index: 1.554
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: Romazarit(CAS DataBase Reference)
    11. NIST Chemistry Reference: Romazarit(109543-76-2)
    12. EPA Substance Registry System: Romazarit(109543-76-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 109543-76-2(Hazardous Substances Data)

109543-76-2 Usage

Uses

Anti-inflammatory; anti-rheumatic.

Check Digit Verification of cas no

The CAS Registry Mumber 109543-76-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,9,5,4 and 3 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 109543-76:
(8*1)+(7*0)+(6*9)+(5*5)+(4*4)+(3*3)+(2*7)+(1*6)=132
132 % 10 = 2
So 109543-76-2 is a valid CAS Registry Number.
InChI:InChI=1/C15H16ClNO4/c1-9-12(8-20-15(2,3)14(18)19)21-13(17-9)10-4-6-11(16)7-5-10/h4-7H,8H2,1-3H3,(H,18,19)

109543-76-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name Romazarit

1.2 Other means of identification

Product number -
Other names 2-[[2-(p-chlorophenyl)-4-methyl-5-oxazolyl]methoxy]-2-methylpropionic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:109543-76-2 SDS

109543-76-2Downstream Products

109543-76-2Relevant articles and documents

Romazarit: A potential disease-modifying antirheumatic drug

Self,Barber,Machin,Osbond,Smithen,Tong,Wickens,Bloxham,Bradshaw,Cashin,Dodge,Lewis,Westmacott

, p. 772 - 777 (2007/10/02)

The synthesis of a series of substituted heterocyclic alkoxypropionic acids is described. They were evaluated for antiinflammatory effects in two animal models of chronic inflammation; adjuvant arthritis and type II collagen arthritis in the rat. The desi

Oxazole and isoxazole derivatives having anti-arthritic activity

-

, (2008/06/13)

Oxazole and isoxazole derivatives of the formula STR1 wherein A is C1-6 -alkylene, Het is a 2-R-oxazol-5-yl, 5-R-oxazol-2-yl, 4-R-oxazol-2-yl, 2-R-oxazol-4-yl, 3-R-isoxazol-5-yl or 5-R-isoxazol-3-yl group which is optionally substituted on the

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