112017-99-9

Basic information

• Product Name: IBUPROFENPICONOL
• Synonyms: Unii-B0F91K5U4n;pyridin-2-ylMethyl 2-(4-isobutylphenyl)propanoate
• CAS NO: 112017-99-9
• Molecular Formula: C19H23NO2
• Molecular Weight: 297.396
• EINECS: 264-979-8
• Mol File: 112017-99-9.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: IBUPROFENPICONOL(CAS DataBase Reference)
• NIST Chemistry Reference: IBUPROFENPICONOL(112017-99-9)
• EPA Substance Registry System: IBUPROFENPICONOL(112017-99-9)

Safety Data

• Hazardous Substances Data: 112017-99-9(Hazardous Substances Data)

Usage

Uses

Used in Pain Management Applications:
Ibuprofenpiconol is used as a topical gel for the treatment of localized musculoskeletal and joint pain, such as arthritis, strains, and sprains. The combination of ibuprofen and piconol works synergistically to reduce inflammation and numb the nerves in the affected area, providing immediate pain relief and long-term anti-inflammatory effects.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Ibuprofenpiconol is utilized as an over-the-counter medication for easy access to consumers seeking relief from localized pain. Its formulation as a topical gel allows for targeted application, reducing the risk of systemic side effects often associated with oral NSAIDs. IBUPROFENPICONOL's well-tolerated nature and dual-action mechanism make it a popular choice for managing various types of localized pain conditions.

InChI:InChI=1/C19H23NO2/c1-14(2)12-16-7-9-17(10-8-16)15(3)19(21)22-13-18-6-4-5-11-20-18/h4-11,14-15H,12-13H2,1-3H3

Upstream product

• 586-98-1 2-Hydroxymethylpyridine 
• 15687-27-1 ibuprofen 
• 2387-23-7 1,3-Dicyclohexylurea 
• 71381-91-4 (+/-)-2-(4-isobutylphenyl)propanoyl chloride 
• 61566-34-5 (+/-)-ibuprofen methyl ester 

Relevant articles and documents

A green chemistry approach to ibuprofen piconol

Ibuprofen piconol synthesis has been described. The use of solid catalyst has demonstrated green chemistry approach with promoted atom economy of 94% compared to the reported 68%.

METHOD FOR PRODUCING ESTER GROUP-CONTAINING COMPOUND

The present invention provides a novel method for producing an ester group-containing compound and a derivative produced using the compound as a synthetic intermediate. The invention also provides a polymerizable composition containing the compound obtained by the production method and a film-shaped polymer obtained by polymerizing the polymerizable composition. The present invention is a method for producing an ester group-containing compound, the method including a mixing step of mixing a condensing agent, a Bronsted acid, a carboxylic acid, and a phenol or an alcohol to prepare a reaction mixture. The Bronsted acid selected is other than the condensing agent, the carboxylic acid, and the phenol.

Method for producing ester group-containing compound being useful for optical material applications such as optical compensation films

The present invention provides a novel method for producing an ester group-containing compound and a derivative produced by using the compound as a synthetic intermediate. The present invention also provides a polymerizable composition containing the compound obtained by the production method and a film-shaped polymer obtained by polymerizing the polymerizable composition. The present invention is a method for producing an ester group-containing compound, the method including a mixing step of mixing a condensing agent, a Bronsted acid, carboxylic acid, and phenol or alcohol to prepare a reaction mixture. The Bronsted acid is selected from anything other than the condensing agent, the carboxylic acid, and the phenol.

ZINC COMPLEX

A zinc complex characterized in exhibiting an octahedral structure and being configured from repeating units represented by general formula (I): wherein L represents a linker region, and R1 represents a C1-4 alkyl group, which can have a halogen atom.

Alterntnate routes for the synthesis of ibuprofen piconol

New, improved and alternate methods for the synthesis of ibuprofen piconol from ibuprofen and pyridine-2-methanol have been demonstrated with different carboxyl activating groups.

Pyridylalkyl esters of 2-(p-isobutylphenyl)acetic acid and propionic acids and use

The present invention relates to phenylacetic acid ester derivatives of the following general formula: STR1 wherein, R is selected from the group consisting of lower alkyl (other than ethyl) and substituted lower alkyl, and R' may be a hydrogen or methyl.