112913-64-1Relevant articles and documents
Site-Specific Incorporation of Multiple Thioamide Substitutions into a Peptide Backbone via Solid Phase Peptide Synthesis
Yang, Jinhua,Wang, Changliu,Yao, Chaochao,Chen, Chunqiu,Hu, Yafang,He, Guifeng,Zhao, Junfeng
, p. 1484 - 1494 (2020/01/02)
Among various peptide modification strategies, thioamide substitution by replacing the carbonyl oxygen atom of an amide bond with a sulfur atom constitutes an invaluable tool for chemical biology, for use in peptide drug discovery and protein structure-fu
SOLUTION PHASE ROUTES FOR WNT HEXAPEPTIDES
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Page/Page column 19, (2020/12/30)
The present disclosure relates generally to the field of polypeptide synthesis, and more particularly, to the solution phase synthesis of the Wnt hexapeptide Foxy-5 and protected derivatives and peptide fragments thereof.
Acid-labile protecting groups for the synthesis of lipidated peptides
Kadereit, Dieter,Deck, Patrick,Heinemann, Ines,Waldmann, Herbert
, p. 1184 - 1193 (2007/10/03)
Lipidated peptides and their neolipoprotein derivatives are efficient tools for the investigation of biological processes in molecular detail. These compounds are often acid- and base-labile, and their synthesis requires the use of a combination of blocki