114150-57-1 Usage
Uses
Used in Pharmaceutical and Agrochemical Synthesis:
4,6-Dioxo-6-phenylhexanoic acid is utilized as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, contributing to the development of new drugs and pesticides. Its unique structure allows for versatile chemical modifications, facilitating the creation of novel compounds with potential therapeutic or pesticidal properties.
Used in Organic Synthesis:
As an intermediate in organic synthesis, 4,6-Dioxo-6-phenylhexanoic acid plays a crucial role in the preparation of various organic compounds. Its reactivity and functional groups enable it to participate in a wide range of chemical reactions, leading to the formation of diverse molecules with potential applications in different industries.
Used in Polymer and Coating Production:
4,6-Dioxo-6-phenylhexanoic acid is employed in the production of polymers and coatings, where its chemical properties contribute to the development of materials with specific characteristics. Its incorporation into polymers can enhance properties such as strength, flexibility, and durability, while its use in coatings can improve adhesion, corrosion resistance, and other desirable attributes.
Used in Medicinal Chemistry and Drug Development:
Due to its unique structure and properties, 4,6-Dioxo-6-phenylhexanoic acid may have potential applications in the field of medicinal chemistry and drug development. Its ability to form stable derivatives and participate in various chemical reactions makes it a valuable building block for the design and synthesis of new pharmaceutical agents with improved efficacy and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 114150-57-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,4,1,5 and 0 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 114150-57:
(8*1)+(7*1)+(6*4)+(5*1)+(4*5)+(3*0)+(2*5)+(1*7)=81
81 % 10 = 1
So 114150-57-1 is a valid CAS Registry Number.
114150-57-1Relevant articles and documents
Synthesis of 1,5-diarylpyrazol-3-propanoic acids towards inhibition of cyclooxygenase-1/2 activity and 5-lipoxygenase-mediated LTB4 formation
Erguen, Burcu Caliskan,Nunez, Maria Teresa,Labeaga, Luis,Ledo, Francisco,Darlington, Janice,Bain, Gretchen,Cakir, Bilge,Banoglu, Erden
scheme or table, p. 497 - 505 (2011/05/09)
A set of 25 derivatives of 3-[1-(6-substituted-pyridazin-3-yl)-5-(4- substitutedphenyl)-1H-pyrazol-3-yl]propanoic acids has been synthesized and evaluated for their in vitro cyclooxygenase-1/2 (COX-1/ 2) inhibitory activity using assays with purified COX-1 and COX-2 enzymes as well as for their 5-lipoxygenase (5-LO)-mediated LTB4 formation inhibitory activity using an assay with activated human polymorphonuclear leukocytes (PMNL). Among the synthesized compounds, especially 4g showed COX-1 (IC50 = 1.5 μM) and COX-2 (IC50 = 1.6 μM) inhibitory activity, whereas compounds 4b and 4 f resulted in the inhibition of 5-LO-mediated LTB4 formation at 14 μM and 12 μM IC50 values, respectively, without any significant inhibition on COX isoforms. ECV · Editio Cantor Verlag.
