114479-33-3

Basic information

• Product Name: [(4-CHLOROBENZYL)AMINO]ACETIC ACID
• Synonyms: [(4-CHLOROBENZYL)AMINO]ACETIC ACID
• CAS NO: 114479-33-3
• Molecular Formula: C₉H₁₀ClNO₂
• Molecular Weight: 199.63
• Mol File: 114479-33-3.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: [(4-CHLOROBENZYL)AMINO]ACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: [(4-CHLOROBENZYL)AMINO]ACETIC ACID(114479-33-3)
• EPA Substance Registry System: [(4-CHLOROBENZYL)AMINO]ACETIC ACID(114479-33-3)

Safety Data

• Hazardous Substances Data: 114479-33-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
[(4-CHLOROBENZYL)AMINO]ACETIC ACID is used as a building block for the synthesis of biologically active compounds, playing a crucial role in the development of new drugs and therapeutic agents. Its unique structure allows for the creation of molecules with potential medicinal properties, contributing to advancements in healthcare.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, [(4-CHLOROBENZYL)AMINO]ACETIC ACID is utilized as a key component in the design and synthesis of novel drug candidates. Its presence in these molecules can influence their pharmacological activity, making it an important tool for researchers in drug discovery.
Used in Agrochemicals:
[(4-CHLOROBENZYL)AMINO]ACETIC ACID may also be employed in the agrochemical industry, potentially serving as a precursor for the development of new pesticides or other agricultural chemicals. Its application in this field could lead to the creation of more effective and environmentally friendly products.
Used in Materials Science:
Furthermore, [(4-CHLOROBENZYL)AMINO]ACETIC ACID has potential applications in materials science, where it could be used to develop new materials with specific properties. Its integration into various material systems may result in innovative products with applications in diverse industries.

Upstream product

• 105-36-2 ethyl bromoacetate 
• 104-86-9 4-chlorobenzylamine 
• 6436-92-6 (4-chlorobenzylamino)acetic acid ethyl ester 
• 104-88-1 4-chlorobenzaldehyde 
• 56-40-6 glycine 

Downstream Products

• 6943-92-6 N-Nitroso-N-<4-chlor-benzyl>-glycin 
• 72836-41-0 3-(4-chloro-benzyl)-sydnone 

Relevant articles and documents

1,2,3-Triazole-boranes: Stable and efficient reagents for ketone and aldehyde reductive amination in organic solvents or in water

Air, moisture and thermally stable 1,2,3-triazole-borane complexes were developed as new practical reagents for ketone/aldehyde amination with high efficiency and excellent substrate diversity.

Design of selective peptidomimetic agonists for the human orphan receptor BRS-3

New tool substances may help to unravel the physiological role of the human orphan receptor BRS-3 and its possible use as a drug target for the treatment of obesity and cancer. In continuation of our work on BRS-3, the solid- and solution-phase synthesis of a library of low molecular weight peptidomimetic agonists based on the recently developed short peptide agonist 4 is described. Functional potencies of the compounds were determined measuring calcium mobilization in a fluorometric imaging plate reader (FLIPR) assay. Focusing on the N-terminus, the D-Phe-Gln moiety of 4 was modified in a combinatorial SAR-oriented medicinal chemistry approach. With the incorporation of N-arylated glycine and alanine building blocks azaglycine, piperazine, or piperidine and the synthesis of semicarbazides and semicarbazones, a number of highly potent and selective compounds with a reduced number of peptide bonds were obtained, which also should have enhanced metabolic stability.