116-63-2

Basic information

• Product Name: 1-Amino-2-naphthol-4-sulfonic acid
• Synonyms: 4-Amino-3-hydroxy-1-naphthalenesulfonic acid, ACS, 98+%;1-AMINO-2-NAPHTHOL-4-SULPHONIC ACID extrapure AR;3-Hydroxynaphthionic acid;4-Amino-3-hydroxy-1-naphthalenesulfonic acid,95%;4-amino-3-hydroxy-1-Naphthalenesulfonic acid 1-amino-2-naphthol-4-sulfonic acid 4-Amino-3-hydroxynaphthalene-1-sulfonic acid;4-Amino-3-hydroxy-1-naphthalenesulfonic acid,1-Amino-2-naphthol-4-sulfonic acid;4-Amino-3-hydroxy-1-naphthalenesulfonic acid p.a.;1-Amino-2-naphthol-4
• CAS NO: 116-63-2
• Molecular Formula: C₁₀H₉NO₄S
• Molecular Weight: 239.25
• EINECS: 204-147-3
• Product Categories: Organic acids;Building Blocks;Chemical Synthesis;Organic Building Blocks;Sulfonic/Sulfinic Acids;Sulfur Compounds;Intermediates of Dyes and Pigments;Sulphur Derivatives
• Mol File: 116-63-2.mol

Chemical Properties

• Melting Point: 290 °C (dec.)(lit.)
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: White to light pink/Powder
• Density: 1.4338 (rough estimate)
• Refractive Index: 1.6500 (estimate)
• Storage Temp.: Store below +30°C.
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: -0.49±0.40(Predicted)
• Water Solubility: insoluble
• Stability: Stable. Incompatible with strong bases, acid chlorides, acid anhydrides, strong oxidizing agents.
• Merck: 14,454
• BRN: 2697469
• CAS DataBase Reference: 1-Amino-2-naphthol-4-sulfonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Amino-2-naphthol-4-sulfonic acid(116-63-2)
• EPA Substance Registry System: 1-Amino-2-naphthol-4-sulfonic acid(116-63-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26
• RIDADR: 3265
• WGK Germany: 3
• RTECS: QK1292000
• TSCA: Yes
• HazardClass: IRRITANT
• PackingGroup: III
• Hazardous Substances Data: 116-63-2(Hazardous Substances Data)

Usage

Uses

Used in Chemical Analysis:
1-Amino-2-naphthol-4-sulfonic acid is used as a reagent in the determination of phosphate. Its chemical properties allow it to interact with phosphate ions, making it a valuable tool in analytical chemistry for detecting and quantifying phosphate levels in various samples.
Used in Dye Industry:
1-Amino-2-naphthol-4-sulfonic acid serves as an intermediate for the production of mordant dyes and acid dyes. Its ability to form complexes with metal ions makes it a crucial component in the synthesis of dyes that exhibit strong colorfastness and resistance to fading.
Used in Pharmaceutical Industry:
Although not explicitly mentioned in the provided materials, 1-Amino-2-naphthol-4-sulfonic acid may also find applications in the pharmaceutical industry as a building block for the synthesis of various drugs and pharmaceutical compounds. Its unique chemical structure can be utilized to create new molecules with potential therapeutic properties.

Purification Methods

Purify it by warming 15g of the acid, 150g of NaHSO3 and 5g of Na2SO3(anhydrous) with 1L of water to ca 90o, shaking until most of the solid had dissolved, then filtering hot. The precipitate obtained by adding 10mL of conc HCl to the cooled filtrate is collected, washed with 95% EtOH until the washings are colourless, and is dried under vacuum over CaCl2. It is stored in a dark-coloured bottle, in the cold [Chanley et al. J Am Chem Soc 74 4347 1952]. [Beilstein 14 IV 2825.]

InChI:InChI=1/C10H9NO4S/c11-10-7-4-2-1-3-6(7)9(5-8(10)12)16(13,14)15/h1-5,12H,11H2,(H,13,14,15)/p-1

Synthetic route

1-Nitroso-2-naphthol (131-91-9) → 1-amino-2-naphthol-4-sulfonic acid (116-63-2)

Conditions	Yield
Stage #1: 1-Nitroso-2-naphthol With iron(III) chloride; pyrographite; sodium hydroxide In water at 60 - 65℃; for 0.75h; Large scale; Stage #2: With hydrazine hydrate In water for 6h; Large scale; Stage #3: With sulfuric acid; sodium sulfite In water at 60 - 65℃; for 12h; pH=7 - 8; Concentration; Reagent/catalyst; Large scale;	98.9%
With sodium disulfite man saeuert bei 30-40grad mit Salzsaeure an;
With sodium hydrogensulfite
With sodium hydrogensulfite

sodium sulfide + bis(4-amino-3-hydroxonaphthalene-1-sulphonic acid)copper + nitrogen(II) oxide (10102-43-9) → 1-amino-2-naphthol-4-sulfonic acid (116-63-2) + C10H8N2O2 + copper(II) sulfide

Conditions	Yield
Stage #1: bis(4-amino-3-hydroxonaphthalene-1-sulphonic acid)copper; nitrogen(II) oxide In methanol at 20℃; for 4h; Stage #2: With air In methanol at 20℃; for 2h; Stage #3: sodium sulfide In methanol; water	A 40% B 40% C n/a

4-amino-1-naphthalenesufonic acid (84-86-6) → 1-amino-2-naphthol-4-sulfonic acid (116-63-2)

Conditions	Yield
With sodium metabisulfite; ammonium peroxydisulfate
With sodium metabisulfite; ozone
With sodium metabisulfite; potassium permanganate

3-chloro-[1,2]naphthoquinone 1-oxime (6639-33-4) → 1-amino-2-naphthol-4-sulfonic acid (116-63-2)

Conditions	Yield
With sodium disulfite Versetzen mit Salzsaeure;

[1,2]naphthoquinone-1-chlorimin (872271-26-6) → 1-amino-2-naphthol-4-sulfonic acid (116-63-2)

Conditions	Yield
With sodium disulfite

3-hydroxy-4-phenylazo-naphthalene-1-sulfonic acid → 1-amino-2-naphthol-4-sulfonic acid (116-63-2)

Conditions	Yield
With hydrogenchloride; tin(ll) chloride

1-amino-naphthalene (134-32-7) → 1-amino-2-naphthol-4-sulfonic acid (116-63-2)

Conditions	Yield
With sodium metabisulfite; ammonium peroxydisulfate
With sodium metabisulfite; ozone
With sodium metabisulfite; potassium permanganate

1-amino-2-naphthol (2834-92-6) → 1-amino-2-naphthol-4-sulfonic acid (116-63-2)

Conditions	Yield
With sodium hydroxide; air; sodium sulfite

β-naphthol (135-19-3) → 1-amino-2-naphthol-4-sulfonic acid (116-63-2)

Conditions	Yield
With sodium hydrogensulfite Reaktion ueber mehrere Stufen;

orange II (573-89-7) → 1-amino-2-naphthol-4-sulfonic acid (116-63-2)

Conditions	Yield
With sodium hydrogensulfite

hydrogenchloride (7647-01-0) + 1-amino-naphthalene (134-32-7) + Na2S2O5 → 1-amino-2-naphthol-4-sulfonic acid (116-63-2)

Conditions	Yield
und anschliessend mit 2S2O8 oder Ozon;

sodium hydrogensulfite + 1-amino-2-naphthol (2834-92-6) + aqueous NaOH-solution + air → 1-amino-2-naphthol-4-sulfonic acid (116-63-2)

4-nitroso-3-hydroxy-naphthoic acid-(2) → 1-amino-2-naphthol-4-sulfonic acid (116-63-2)

Conditions	Yield
With sodium hydrogensulfite anschliessendes Erwaermen mit wss. Salzsaeure;

dipotassium-salt of/the/ 4-<4-sulfo-phenylazo>-3-hydroxy-naphthalene-sulfonic acid-(1) → 1-amino-2-naphthol-4-sulfonic acid (116-63-2)

Conditions	Yield
With sodium hydrogensulfite Behandeln des danach isolierten N-Sulfo-Derivats mit wss. Salzsaeure;

sodium-salt of/the/ (+-)-3-oxo-4-hydroxyimino-1.2.3.4-tetrahydro-naphthalene-sulfonic acid-(1) → 1-amino-2-naphthol-4-sulfonic acid (116-63-2)

Conditions	Yield
With ammonium chloride; zinc
With hydrogenchloride; tin(ll) chloride

4-hydroxyimino-3-oxo-3,4-dihydro-[2]naphthoic acid + aqueous sodium hydrogen sulfite → 1-amino-2-naphthol-4-sulfonic acid (116-63-2)

Conditions	Yield
anschliessendes Behandeln mit wss. Salzsaeure;

hydrogenchloride (7647-01-0) + 2-hydroxy-1-hydroxyimino-1,2-dihydro-naphthalene-2-sulfonic acid ; sodium-salt (93113-57-6) + SnCl2 → 1-amino-2-naphthol-4-sulfonic acid (116-63-2)

2-hydroxy-1-hydroxyimino-1,2-dihydro-naphthalene-2-sulfonic acid ; sodium-salt (93113-57-6) + zinc-powder + aqueous NH4Cl solution → 1-amino-2-naphthol-4-sulfonic acid (116-63-2)

Conditions	Yield
at 13 - 27℃;

hydrogenchloride (7647-01-0) + 2-hydroxy-1-hydroxyimino-1,2-dihydro-naphthalene-2-sulfonic acid ; sodium-salt (93113-57-6) + zinc-powder → 1-amino-2-naphthol-4-sulfonic acid (116-63-2) + 1-amino-2-hydroxy-1,2-dihydro-naphthalene-2-sulfonic acid

Conditions	Yield
at 8 - 12℃;

sodium-salt of/the/ (+-)-3-oxo-4-hydroxyimino-1.2.3.4-tetrahydro-naphthalene-sulfonic acid-(1) → 1-amino-2-naphthol-4-sulfonic acid (116-63-2) + 4-amino-3-oxo-1,2,3,4-tetrahydro-naphthalene-1-sulfonic acid

Conditions	Yield
With hydrogenchloride; zinc

orange II (633-96-5) + NaHSO3 → 1-amino-2-naphthol-4-sulfonic acid (116-63-2) + 4-aminobenzene sulfonic acid (121-57-3)

Conditions	Yield
bei folgendem Ansaeuern mit Salzsaeure;

2-naphthol-4-sulfonic acid (6357-85-3) → 1-amino-2-naphthol-4-sulfonic acid (116-63-2)

Conditions	Yield
Multi-step reaction with 2 steps 1: sodium bicarbonate 2: tin (II)-chloride; diluted hydrochloric acid View Scheme

3-chloro-2-naphthol (56541-64-1) → 1-amino-2-naphthol-4-sulfonic acid (116-63-2)

Conditions	Yield
Multi-step reaction with 3 steps 1: potassium sulfite / 120 °C 2: sodium bicarbonate 3: tin (II)-chloride; diluted hydrochloric acid View Scheme

1,3-dichloronaphthol (116632-06-5) → 1-amino-2-naphthol-4-sulfonic acid (116-63-2)

Conditions	Yield
Multi-step reaction with 3 steps 1: potassium sulfite / 170 °C 2: sodium bicarbonate 3: tin (II)-chloride; diluted hydrochloric acid View Scheme

sodium metabisulfite + 1-hydroxylimino-2-tetralone-4-sulfonic acid (86771-68-8) + β-naphthol (135-19-3) → 1-amino-2-naphthol-4-sulfonic acid (116-63-2)

Conditions	Yield
With sulfuric acid In water

sodium hydrogensulfite + 1-Nitroso-2-naphthol (131-91-9) → 1-amino-2-naphthol-4-sulfonic acid (116-63-2)

Conditions	Yield
In not given
In not given

1-amino-naphthalene (134-32-7) + ozone (10028-15-6) + sodium hydrogensulfite → 1-amino-2-naphthol-4-sulfonic acid (116-63-2)

Conditions	Yield
In not given days, 0°C, 2.5 % NaHSO3 soln.;
In not given days, 0°C, 2.5 % NaHSO3 soln.;

1-amino-naphthalene (134-32-7) + peroxodisulfate ion (15092-81-6) + sodium hydrogensulfite → 1-amino-2-naphthol-4-sulfonic acid (116-63-2)

Conditions	Yield
In not given days, 0°C, 2.5 % NaHSO3 soln.;
In not given days, 0°C, 2.5 % NaHSO3 soln.;

1-amino-2-naphthol-4-sulfonic acid (116-63-2) + 4-nitrobenzaldehdye (555-16-8) + triethylamine (121-44-8) → triethylammonium 3-hydroxy-4-(4-nitrobenzylidene)amino-1-naphthalenesulfonate

Conditions	Yield
In ethanol for 1h; Heating;	100%

1-amino-2-naphthol-4-sulfonic acid (116-63-2) + 4-chlorobenzaldehyde (104-88-1) → sodium 2-(4-chlorophenyl)naphtho[1,2-d]oxazole-5-sulfonate

Conditions	Yield
Stage #1: 1-amino-2-naphthol-4-sulfonic acid With sodium hydroxide In ethanol for 0.166667h; Stage #2: 4-chlorobenzaldehyde In ethanol at 20℃; for 12h;	95%

6-Amino-1,3-dimethylbarbituric acid (6642-31-5) + 1-amino-2-naphthol-4-sulfonic acid (116-63-2) → C16H15N5O6S (1242060-38-3)

Conditions	Yield
Stage #1: 1-amino-2-naphthol-4-sulfonic acid With sulfuric acid; acetic acid; zinc(II) chloride; sodium nitrite at 0 - 5℃; for 2h; Stage #2: 6-Amino-1,3-dimethylbarbituric acid With sodium hydroxide In water at 0 - 5℃; for 0.333333h; pH=7;	94%

2,3-dihydroxybenzaldehyde (24677-78-9) + 1-amino-2-naphthol-4-sulfonic acid (116-63-2) → sodium 4-(2,3-dihydroxybenzylideneamino)-3-hydroxynaphthalene-1-sulfonate

Conditions	Yield
Stage #1: 1-amino-2-naphthol-4-sulfonic acid With sodium hydroxide In ethanol for 0.166667h; Stage #2: 2,3-dihydroxybenzaldehyde In ethanol at 20℃; for 12h;	91%

2-phenyl-4H-3,1-benzoxazin-4-one (1022-46-4) + 1-amino-2-naphthol-4-sulfonic acid (116-63-2) → 3-hydroxy-4-(4-oxo-2-phenylquinazolin-3(4H)-yl)naphthalene-1-sulfonic acid

Conditions	Yield
With pyridine for 6h; Reflux;	91%

1-amino-2-naphthol-4-sulfonic acid (116-63-2) + terephthalaldehyde, (623-27-8) + triethylamine (121-44-8) → 2-(4-formylphenyl)naphtho[1,2-d]oxazole-5-sulfonic acid triethylamine

Conditions	Yield
In ethanol at 20℃; for 24h;	90%

1-amino-2-naphthol-4-sulfonic acid (116-63-2) + p-toluidine (106-49-0) → 4-amino-3-hydroxy-2-p-tolylazo-naphthalene-1-sulfonic acid

Conditions	Yield
Stage #1: p-toluidine With hydrogenchloride; sodium nitrite In water at 0 - 5℃; for 0.5h; Stage #2: 1-amino-2-naphthol-4-sulfonic acid In water at 20℃; for 0.5h; pH=6 - 6.5;	90%

bismuth(III) tert-butoxide + 1-amino-2-naphthol-4-sulfonic acid (116-63-2) → Bi(3+)*3C10H8NO4S(1-)

Conditions	Yield
In tetrahydrofuran at -78 - 20℃; Inert atmosphere;	88%

1-amino-2-naphthol-4-sulfonic acid (116-63-2) + n-hexadecanoyl chloride (112-67-4) → 2'-pentadecylnaphth<3,4-d>oxazole-1-sulfonic acid

Conditions	Yield
With triethylamine In N,N-dimethyl-formamide at 150 - 160℃; for 20h;	87%

1-amino-2-naphthol-4-sulfonic acid (116-63-2) + Triethyl orthopropionate (115-80-0) → 2-ethyl-naphtho[1,2-d]oxazole-5-sulfonic acid ethyl ester

Conditions	Yield
With N,N-dimethyl acetamide; toluene-4-sulfonic acid for 0.05h; microwave irradiation;	86%

pyridine (110-86-1) + nickel(II) acetate hydrate + 1-amino-2-naphthol-4-sulfonic acid (116-63-2) + 2-hydroxynaphthalene-1-carbaldehyde (708-06-5) + potassium hydroxide → (C21NH12(O)2SO3)Ni(NC5H5)(1-)*K(1+)=KNi(C21NH12(O)2SO3)(C5H5N) (208240-76-0)

Conditions	Yield
In ethanol heating, stirring; elem. anal., thermal analysis;	85%

1-amino-2-naphthol-4-sulfonic acid (116-63-2) + 4-methyl-benzaldehyde (104-87-0) → sodium 2-(4-methylphenyl)naphtho[1,2-d]oxazole-5-sulfonate

Conditions	Yield
Stage #1: 1-amino-2-naphthol-4-sulfonic acid With sodium hydroxide In ethanol for 0.166667h; Stage #2: 4-methyl-benzaldehyde In ethanol at 20℃; for 12h;	85%

1-amino-2-naphthol-4-sulfonic acid (116-63-2) + n-hexadecanoyl chloride (112-67-4) → 4-amino-3-(palmitoyloxy)-1-naphthalenesulfonic acid

Conditions	Yield
With pyridine for 25h; Heating;	84%

1-amino-2-naphthol-4-sulfonic acid (116-63-2) + Triethyl orthoacetate (78-39-7) → 2-methyl-naphtho[1,2-d]oxazole-5-sulfonic acid ethyl ester

Conditions	Yield
With N,N-dimethyl acetamide for 0.05h; microwave irradiation;	84%

pyridine (110-86-1) + zinc(II) acetate hydrate + 1-amino-2-naphthol-4-sulfonic acid (116-63-2) + 2-hydroxynaphthalene-1-carbaldehyde (708-06-5) + potassium hydroxide → (C21NH12(O)2SO3)Zn(NC5H5)(1-)*K(1+)=KZn(C21NH12(O)2SO3)(C5H5N) (208240-78-2)

Conditions	Yield
In ethanol heating, stirring; elem. anal., thermal analysis;	84%

zinc(II) acetate hydrate + 1-amino-2-naphthol-4-sulfonic acid (116-63-2) + 2-hydroxynaphthalene-1-carbaldehyde (708-06-5) + potassium hydroxide → (C21NH12(O)2SO3)Zn(H2O)(1-)*K(1+)*H2O=KZn(C21NH12(O)2SO3)*2H2O (208240-74-8)

Conditions	Yield
In ethanol heating, stirring; elem. anal., thermal analysis;	84%

1-amino-2-naphthol-4-sulfonic acid (116-63-2) → 3,4-dioxo-3,4-dihydro-naphthalene-1-sulfonic acid (2066-93-5)

Conditions	Yield
With recombinant CotA-laccase from Bacillus subtilis In aq. phosphate buffer at 37℃; pH=7; Kinetics; Enzymatic reaction;	83%
With nitric acid
With water; nitric acid at 25 - 30℃; Darst.;

1,1,1-trimethoxybutane (43083-12-1) + 1-amino-2-naphthol-4-sulfonic acid (116-63-2) → 2-propyl-naphtho[1,2-d]oxazole-5-sulfonic acid methyl ester

Conditions	Yield
With toluene-4-sulfonic acid for 6h; Heating;	83%

pyridine (110-86-1) + 1-amino-2-naphthol-4-sulfonic acid (116-63-2) + cobalt(II) diacetate tetrahydrate (6147-53-1) + 2-hydroxynaphthalene-1-carbaldehyde (708-06-5) + potassium hydroxide → (C21NH12(O)2SO3)Co(NC5H5)(1-)*K(1+)=KCo(C21NH12(O)2SO3)(C5H5N) (208240-75-9)

Conditions	Yield
In ethanol heating, stirring; elem. anal., thermal analysis;	83%

trimethyl orthovalerate (13820-09-2) + 1-amino-2-naphthol-4-sulfonic acid (116-63-2) → 2-butyl-naphtho[1,2-d]oxazole-5-sulfonic acid methyl ester

Conditions	Yield
With N,N-dimethyl acetamide; toluene-4-sulfonic acid for 0.025h; microwave irradiation;	82%

N,N’-(dimethylethylenediaminothiosemicarbazanato)-4-(methylthiosemicarbazanato)butane-2,3-diimine (1218759-53-5) + 1-amino-2-naphthol-4-sulfonic acid (116-63-2) → C2H7N*C17H20N6O4S3 (1229570-77-7)

Conditions	Yield
In acetonitrile Reflux; Inert atmosphere;	82%

1,10-phenanthroline-5,6-dione (27318-90-7) + 1-amino-2-naphthol-4-sulfonic acid (116-63-2) → 4-(6-oxo-[1,10]phenanthroline-5-ylideneamino)-3-hydroxynaphthalene-1-sulfonic acid (1612888-71-7)

Conditions	Yield
In ethanol for 4h; Reflux;	82%

pyridine (110-86-1) + furfural (98-01-1) + nickel(II) acetate hydrate + 1-amino-2-naphthol-4-sulfonic acid (116-63-2) → potassium bispyridinebis[N-(furfuryliden)-1-amino-2-oxidonaphthalene-4-sulfonato]nickel(II) pentahydrate

Conditions	Yield
In ethanol pH 8; ppt. filtration, washing, air drying; elem. anal.;	81%

1-amino-2-naphthol-4-sulfonic acid (116-63-2) + 2-amino-4-fluorobenzoyl fluoride → C17H11F2N3O5S

Conditions	Yield
Stage #1: 2-amino-4-fluorobenzoyl fluoride With hydrogenchloride; sodium nitrite In water at 0 - 5℃; Stage #2: 1-amino-2-naphthol-4-sulfonic acid With sodium carbonate In water at 0 - 5℃; for 0.666667h; pH=7.5 - 8.5;	81%

picoline (108-89-4) + furfural (98-01-1) + zinc(II) acetate hydrate + 1-amino-2-naphthol-4-sulfonic acid (116-63-2) → potassium bis(4-methylpyridine)bis[N-(furfuryliden)-1-amino-2-oxidonaphthalene-4-sulfonato]zinc(II) monohydrate

Conditions	Yield
In ethanol pH 8; ppt. filtration, washing, air drying; elem. anal.;	80%

picoline (108-89-4) + furfural (98-01-1) + 1-amino-2-naphthol-4-sulfonic acid (116-63-2) + cobalt(II) diacetate tetrahydrate (6147-53-1) → potassium bis(4-methylpyridine)bis[N-(furfuryliden)-1-amino-2-oxidonaphthalene-4-sulfonato]cobalt(II) tetrahydrate

Conditions	Yield
In ethanol pH 8; ppt. filtration, washing, air drying; elem. anal.;	80%

pyridine (110-86-1) + 1-amino-2-naphthol-4-sulfonic acid (116-63-2) + cobalt(II) diacetate tetrahydrate (6147-53-1) + salicylaldehyde (90-02-8) + potassium hydroxide → (C17NH10(O)2SO3)Co(NC5H5)(1-)*K(1+)=K[Co(C17NH10(O)2SO3)(C5NH5)] (208240-57-7)

Conditions	Yield
In ethanol pH 8 to 9, reaction in hot suspension; elem. anal., thermal analysis;	80%

pyridine (110-86-1) + copper(II) acetate hydrate + 1-amino-2-naphthol-4-sulfonic acid (116-63-2) + 2-hydroxynaphthalene-1-carbaldehyde (708-06-5) + potassium hydroxide → (C21NH12(O)2SO3)Cu(NC5H5)(1-)*K(1+)=KCu(C21NH12(O)2SO3)(C5H5N) (208240-77-1)

Conditions	Yield
In ethanol heating, stirring; elem. anal., thermal analysis;	80%

3-Methylpyridine (108-99-6) + zinc(II) acetate hydrate + 1-amino-2-naphthol-4-sulfonic acid (116-63-2) + salicylaldehyde (90-02-8) + potassium hydroxide → (C17NH10(O)2SO3)Zn(NC5H4CH3)(1-)*K(1+)=K[Zn(C17NH10(O)2SO3)(C5NH4CH3)] (208240-69-1)

Conditions	Yield
In ethanol pH 8 to 9, reaction in hot suspension; elem. anal., thermal analysis;	80%

Upstream product

• 84-86-6 4-amino-1-naphthalenesufonic acid 
• 6639-33-4 3-chloro-[1,2]naphthoquinone 1-oxime 
• 872271-26-6 [1,2]naphthoquinone-1-chlorimin 
• 134-32-7 1-amino-naphthalene 
• 2834-92-6 1-amino-2-naphthol 
• 135-19-3 β-naphthol 
• 573-89-7 orange II 
• 131-91-9 1-Nitroso-2-naphthol 
• 7647-01-0 hydrogenchloride 
• 93113-57-6 2-hydroxy-1-hydroxyimino-1,2-dihydro-naphthalene-2-sulfonic acid ; sodium-salt 
• 633-96-5 orange II 
• 6357-85-3 2-naphthol-4-sulfonic acid 
• 56541-64-1 3-chloronaphthalen-2-ol 
• 116632-06-5 1,3-dichloronaphthol 

Downstream Products

• 887-76-3 2-hydroxy-4-sulfo-naphthalene-1-diazonium-betaine 
• 2066-93-5 3,4-dioxo-3,4-dihydro-naphthalene-1-sulfonic acid 
• 27828-56-4 4-(phenylamino)naphthalene-1,2-dione 
• 6259-63-8 6-Nitro-1-amino-2-naphthol-4-sulfonsaeure 
• 18398-37-3 3,4-Dibrom-1,2-naphthochinon 
• 88-99-3 benzene-1,2-dicarboxylic acid 
• 23792-56-5 2-benzeneazo-1-naphthol-4-sulfonic acid 
• 84-23-1 1,2-diazooxy-4-naphthalenesulfonic acid 
• 52469-52-0 2-(4-chloro-phenyl)-naphtho[1,2-d]oxazole-5-sulfonic acid 
• 52470-14-1 2-(3-nitro-phenyl)-naphtho[1,2-d]oxazole-5-sulfonic acid 
• 52469-45-1 2-(4-nitro-phenyl)-naphtho[1,2-d]oxazole-5-sulfonic acid 
• 52469-70-2 2-(4-hydroxy-phenyl)-naphtho[1,2-d]oxazole-5-sulfonic acid 
• 52469-53-1 2-(4-bromo-phenyl)-naphtho[1,2-d]oxazole-5-sulfonic acid 
• 52777-33-0 2-(4-cyano-phenyl)-naphtho[1,2-d]oxazole-5-sulfonic acid 

Relevant articles and documents

Aromatic C-nitrosation by a copper(ii)-nitrosyl complex

Copper(ii) complex of 4-amino-3-hydroxy-1-sulphonic acid was synthesized and characterized. Upon addition of nitric oxide, the copper(ii) center of the complex in methanol was found to undergo reduction through an unstable copper(ii)-nitrosyl intermediate. The formation of the intermediate was confirmed by UV-visible and FT-IR spectroscopy. The reduction of the copper(ii) center was accompanied with a simultaneous C-nitrosation of the aromatic ring of the ligand. The C-nitrosation product was isolated and characterized by various spectroscopic analyses. This journal is

1-nitroso-2-naphthol hydrazine hydrate reduction method

The invention provides a 1-nitroso-2-naphthol hydrazine hydrate reduction method.A ferric chloride and activated carbon system under the alkaline condition is selected for catalytic reduction, production cost is low, the yield of products is increased, and the purity of the products is improved.After tetrabutylammonium bromide and 1-butanesulfonic acid are added, the catalytic effect of the ferric chloride and activated carbon system under the alkaline condition can be improved, the yield of the products is further increased, and the purity of the products is further improved.Hydrazine hydrate reduction is an environment-friendly reduction method, in many literatures, the hydrazine hydrate reduction is mostly benzene nitride or nitrosation product hydrazine hydrate reduction, and hydrazine hydrate reduction containing naphthalene nitride does not exist.According to the method, part of hydrazine hydrate replaces sodium sulfite to serve as a reduction agent, generation of inorganic salt is reduced, acid consumption is reduced, the yield of products can be increased, and the purity of the products can also be improved.

Process for the preparation of 1-amino-2-naphthol-4-sulfonic acid

Process for the preparation of 1-amino-2-naphthol-4-sulfonic acid by treating 1-hydroxylamino-2-tetralone-4-sulfoniuc acid with an alkali metal pyrosulfite in mineral acid medium in the presence of catalytic amounts of a copper compound. 1-Amino-2-naphthol-4-sulfonic acid is an intermediate for the manufacture of dyes.

Unsymmetrical 1:2-chromium complexes containing an azo compound and an azomethine compound

Compounds of the formula: STR1 WHICH ARE EMINENTLY SUITABLE FOR DYEING NATURAL AND SYNTHETIC POLYAMIDES AND FOR COLORING SURFACE COATINGS. Dyeings on textile material are distinguished by very good lightfastness and very good fastness to wet treatments, for example fastness to water, perspiration, sea water and washing.

Aromatic azo sulfonylnitrene compounds

Compounds of the structure SPC1 Wherein R and R1 are the same or different and are selected from the group consisting of hydrogen, halogen, and alkyl from one to four carbon atoms, inclusive, and R2 is a substance which inhibits thrombogenic or clotting activity of a material and is that portion of a substituted aromatic which couples with a diazonium salt.