887-76-3

Basic information

• Product Name: 1-Diazo-2-naphthol-4-sulfonic acid
• Synonyms: 1-Diazo-2-naphthol-4-sulfonic acid powder;1,2-diazoxynaphthalene-4-sulfnic acid;1,2-Naphthoxydiazde-4-sulfonicacid;1-naphthalenediazonium,2-hydroxy-4-sulfo-,hydroxide,innersalt;1-Naphthalenediazonium,2-hydroxy-4-sulfo-,innersalt;4,4’-azo-3-hydroxynaphthalene-1-sulfonate;1,2-Naphthoxydiazo-4-sulfonic acid;1-DIAZO-2-NAPHTHOL-4-SULFONIC ACID
• CAS NO: 887-76-3
• Molecular Formula: C₁₀H₆N₂O₄S
• Molecular Weight: 252.25
• EINECS: 212-958-9
• Product Categories: Azo/Diazo Compounds;Nitrogen Compounds;Organic Building Blocks
• Mol File: 887-76-3.mol
• Article Data: 0

Chemical Properties

• Melting Point: 160 °C (dec.)(lit.)
• Boiling Point: 160 C
• Flash Point: 微溶于水，溶于碱。
• Appearance: brown adhering powder or paste
• Density: 1.5366 (rough estimate)
• Refractive Index: 1.6800 (estimate)
• Storage Temp.: Flammables area
• Water Solubility: 15.8 g/L (20 ºC)
• CAS DataBase Reference: 1-Diazo-2-naphthol-4-sulfonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Diazo-2-naphthol-4-sulfonic acid(887-76-3)
• EPA Substance Registry System: 1-Diazo-2-naphthol-4-sulfonic acid(887-76-3)

Safety Data

• Hazard Codes: F,C
• Statements: 5-11-34
• Safety Statements: 16-26-36/37/39-45-48
• RIDADR: UN 2925 4.1/PG 2
• WGK Germany: 3
• TSCA: Yes
• HazardClass: 4.1
• PackingGroup: III
• Hazardous Substances Data: 887-76-3(Hazardous Substances Data)

Usage

Chemical Properties

brown adhering powder or paste

Uses

Involved in studies to analyze structure-activity relationships to predict biodegradability of N-heterocycles in wastewater and polluted soilReactant used as hydrazinonaphthalene and azonaphthalene thrombopoietin mimics acting as nonpeptidyl promoters of megakaryocytopoiesis

General Description

The degradation and adsorption of 1-diazo-2-naphthol-4-sulfonic acid was studied using sewage sludge derived porous carbon.

InChI:InChI=1/C10H8N2O4S/c11-12-10-7-4-2-1-3-6(7)9(5-8(10)13)17(14,15)16/h1-5,8,13H,(H,14,15,16)

Synthetic route

1-amino-2-naphthol-4-sulfonic acid (116-63-2) → 2-hydroxy-4-sulfo-naphthalene-1-diazonium-betaine (887-76-3)

Conditions	Yield
With copper(I) sulfate; water; copper(II) sulfate; sodium nitrite
With water; sodium chloride; sodium nitrite
With zinc nitrite das Zinksalz entsteht;

2-acetoxy-4-sulfo-naphthalene-1-diazonium-betaine → 2-hydroxy-4-sulfo-naphthalene-1-diazonium-betaine (887-76-3)

Conditions	Yield
With water

salt of/the/ 1-amino-naphthol-(2)-sulfonic acid-(4) → 2-hydroxy-4-sulfo-naphthalene-1-diazonium-betaine (887-76-3)

Conditions	Yield
With zinc nitrite; sodium nitrite das Zinksalz entsteht;
With zinc nitrite das Zinksalz entsteht;
With mercury(II) nitrite das Quecksilbersalz entsteht;

1-amino-2-naphthol-4-sulfonic acid (116-63-2) + copper(II) sulfate (7758-99-8) + sodium nitrite → 2-hydroxy-4-sulfo-naphthalene-1-diazonium-betaine (887-76-3)

1-amino-2-naphthol-4-sulfonic acid (116-63-2) + zinc sulfate + sodium nitrite → 2-hydroxy-4-sulfo-naphthalene-1-diazonium-betaine (887-76-3)

ethanol (64-17-5) + 2-hydroxy-4-sulfo-naphthalene-1-diazonium-betaine (887-76-3) → 2-naphthol-4-sulfonic acid (6357-85-3)

2-hydroxy-4-sulfo-naphthalene-1-diazonium-betaine (887-76-3) + 1-hydroxy-4-sulfo-naphthalene-2-diazonium-betaine (887-77-4) → 3-hydroxy-4-(3-sulfo-inden-1-ylazo)-naphthalene-1-sulfonic acid

Conditions	Yield
With hydrogenchloride; sodium hydroxide Irradiation.Ansaeuern mit wss.Salzsaeure;

2-hydroxy-4-sulfo-naphthalene-1-diazonium-betaine (887-76-3) → 3-hydroxy-4-(3-sulfo-inden-1-ylazo)-naphthalene-1-sulfonic acid

Conditions	Yield
With hydrogenchloride; sodium hydroxide Irradiation.Ansaeuern mit wss.Salzsaeure;

2-hydroxy-4-sulfo-naphthalene-1-diazonium-betaine (887-76-3) → 6-chloro-2-hydroxy-4-sulfo-naphthalene-1-diazonium-betaine

Conditions	Yield
With sulfuric acid under 5320 - 6080 Torr; bei der Chlorieren;
With chlorosulfonic acid under 5320 - 6080 Torr; bei der Chlorieren;
With chlorine at 70℃;
With chlorosulfonic acid under 5320 - 6080 Torr; bei der Chlorieren;
With sulfuric acid under 5320 - 6080 Torr; bei der Chlorieren;

2-hydroxy-4-sulfo-naphthalene-1-diazonium-betaine (887-76-3) → 6-bromo-2-hydroxy-4-sulfo-naphthalene-1-diazonium-betaine

Conditions	Yield
With chlorosulfonic acid; bromine at 60 - 65℃;
With sulfuric acid; bromine; iodine at 70 - 75℃;

2-hydroxy-4-sulfo-naphthalene-1-diazonium-betaine (887-76-3) → 2-hydroxy-6-nitro-4-sulfo-naphthalene-1-diazonium-betaine (586387-97-5)

Conditions	Yield
With sulfuric acid; nitric acid at 0 - 5℃;

2-hydroxy-4-sulfo-naphthalene-1-diazonium-betaine (887-76-3) → 1-sulfo-indene-3-carboxylic acid ; sodium-salt

Conditions	Yield
With hydrogenchloride Irradiation.mit Sonnenlicht;

2-hydroxy-4-sulfo-naphthalene-1-diazonium-betaine (887-76-3) + β-naphthol (135-19-3) → Calcon (2538-79-6)

Conditions	Yield
in alkal. Loesung;

2-hydroxy-4-sulfo-naphthalene-1-diazonium-betaine (887-76-3) + NaOH/KOH + sodium sulfide → 2-naphthol-4-sulfonic acid (6357-85-3)

chlorosulfonic acid (7790-94-5) + 2-hydroxy-4-sulfo-naphthalene-1-diazonium-betaine (887-76-3) → 2-hydroxy-4.x-bis-chlorosulfonyl-naphthalenediazonium-(1)-betaine

2-hydroxy-4-sulfo-naphthalene-1-diazonium-betaine (887-76-3) + aqueous sodium sulfite → 2-hydroxy-naphthalene-disulfonic acid-(1.4)

Conditions	Yield
Erhitzen des Reaktionsgemisches mit Kupfer(II)-sulfat und Kupfer; das Natrium-Salz reagiert;

2-hydroxy-4-sulfo-naphthalene-1-diazonium-betaine (887-76-3) + HNO3+H2SO4 → 2-hydroxy-6-nitro-4-sulfo-naphthalene-1-diazonium-betaine (586387-97-5)

hydrogenchloride (7647-01-0) + 2-hydroxy-4-sulfo-naphthalene-1-diazonium-betaine (887-76-3) → 3-sulfo-indene-carboxylic acid-(1)

Conditions	Yield
Sonnenlicht oder UV-Licht.Irradiation;

chlorosulfonic acid (7790-94-5) + 2-hydroxy-4-sulfo-naphthalene-1-diazonium-betaine (887-76-3) + chlorine (7782-50-5) → x-chloro-2-oxy-naphthalene-sulfonic acid-(4)-diazonium hydroxide-(1)

2-hydroxy-4-sulfo-naphthalene-1-diazonium-betaine (887-76-3) + sulfuric acid (7664-93-9) + chlorine (7782-50-5) → x-chloro-2-oxy-naphthalene-sulfonic acid-(4)-diazonium hydroxide-(1)

Upstream product

• 116-63-2 1-amino-2-naphthol-4-sulfonic acid 
• 7758-99-8 copper(II) sulfate 

Downstream Products

• 6357-85-3 2-naphthol-4-sulfonic acid 
• 586387-97-5 2-hydroxy-6-nitro-4-sulfo-naphthalene-1-diazonium-betaine 
• 2538-79-6 Calcon