116569-00-7

Basic information

• Product Name: 3-(Methoxycarbonyl)cyclobutanecarboxylicacid
• Synonyms: 3-(methoxycarbonyl)cyclobutane-1-carboxylic acid;1,3-Cyclobutanedicarboxylic acid monomethyl ester
• CAS NO: 116569-00-7
• Molecular Formula: C₇H₁₀O₄
• Molecular Weight: 158.1519
• Mol File: 116569-00-7.mol

Chemical Properties

• Boiling Point: 269.9±33.0 °C(Predicted)
• Appearance: /
• Density: 1.308±0.06 g/cm3(Predicted)
• PKA: 4.45±0.40(Predicted)
• CAS DataBase Reference: 3-(Methoxycarbonyl)cyclobutanecarboxylicacid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(Methoxycarbonyl)cyclobutanecarboxylicacid(116569-00-7)
• EPA Substance Registry System: 3-(Methoxycarbonyl)cyclobutanecarboxylicacid(116569-00-7)

Safety Data

• Hazardous Substances Data: 116569-00-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
3-(Methoxycarbonyl)cyclobutanecarboxylic acid is used as a key intermediate in the synthesis of new drugs and bioactive compounds. Its unique structure and reactivity contribute to the development of innovative pharmaceutical agents with potential therapeutic applications.
Used in Organic Synthesis:
3-(Methoxycarbonyl)cyclobutanecarboxylic acid serves as a versatile building block in organic synthesis, enabling the creation of a wide range of chemical compounds. Its functional group can be further modified or reacted with other molecules, facilitating the synthesis of complex organic structures.
Used in Specialty Chemicals Production:
3-(Methoxycarbonyl)cyclobutanecarboxylic acid is utilized in the production of specialty chemicals and materials for various industrial applications. Its unique properties can be harnessed to create high-value products with specific characteristics, such as enhanced stability, reactivity, or selectivity.

Upstream product

• 61752-11-2 methyl 3-oxo-2-oxabicyclo<2.2.0>hept-5-ene-6-carboxylate 
• 142733-60-6 2,2‐diethyl 7‐phenyl‐6,8‐dioxaspiro[3.5]nonane‐2,2‐dicarboxylate 
• 77614-64-3 7‐phenyl‐6,8‐dioxaspiro[3.5]nonane‐2,2‐dicarboxylic acid 
• 67-56-1 methanol 
• 4462-97-9 cis-1,3-Cyclobutandicarbonsaeureanhydrid 
• 7371-69-9 1,1,3,3-cyclobutanetetracarboxylic acid 
• 6018-41-3 methyl coumalate 
• 4462-97-9 cis-cyclobutane-1,3-dicarboxylic acid anhydride 

Downstream Products

• 1349709-10-9 C₂₃H₂₆O₉ 
• 1363332-44-8 C₃₃H₃₆N₂O₉ 
• 1346648-43-8 C₁₄H₁₇NO₃S 
• 142733-63-9 cis-methyl 3-<(t-butoxycarbonyl)amino>cyclobutanecarboxylate 
• 142733-62-8 cis-methyl 3-carboxamidocyclobutanecarboxylate 
• 2398-17-6 cis-Methyl-3-hydroxymethyl-cyclobutan-carboxylat 

Relevant articles and documents

Scale-up synthesis of a deuterium-labeled cis-cyclobutane-1,3-Dicarboxylic acid derivative using continuous photo flow chemistry

Continuous photo flow synthesis of tert-butyl 3-oxo-2-oxabicyclo[2.2.0]hex-5-ene-6-carboxylate (2b) from tert-butyl 2-oxo-2H-pyran-5-carboxylate (1b) has been investigated for scale-up synthesis of cis-3-(tert-butoxycarbonyl)-2,3,4-d3-cyclobuta

Total synthesis and structural revision of the piperarborenines: When photochemistry meets C-H activation

Activate and reiterate: The activation of C(sp3)-H bonds is a highly desirable transformation because molecular complexity can be increased at the expense of the most simple and readily available organic linkage. In recent contributions this ap

Total synthesis and structural revision of the piperarborenines via sequential cyclobutane C-H arylation

A strategy for the construction of unsymmetrical cyclobutanes using C-H functionalization logic is demonstrated in the total synthesis of piperarborenine B and piperarborenine D (reported structure). These syntheses feature a new preparation of cis-cyclob

SYNTHESIS OF NEW CARBOCYCLIC ANALOGUES OF OXETANOCIN A AND OXETANOCIN G

The synthesis of cis-3-amino-1-cyclobutanemethanol has been performed in six steps (59.6percent yield) from cis-1,3-cyclobutanedicarboxylic anhydride.This allowed us to obtain two new carbocyclic analogues of oxetanocin A and oxetanocin G related to 7-deazaadenosine and 7-deazaguanosine.