116690-73-4

Upstream product

• 719-59-5 5-chloro-2-aminobenzophenone 
• 502-42-1 cycloheptanone 
• 144930-52-9 (4-chlorophenyl)(phenyl)iodonium triflate 
• 629-03-8 1 ,6-dibromohexane 
• 536-74-3 phenylacetylene 
• 24214-80-0 cycloheptanone benzoylhydrazone 

Relevant academic research and scientific papers

Green synthesis of trimetallic oxide nanoparticles and their use as an efficient catalyst for the green synthesis of quinoline and spirooxindoles: Antibacterial, cytotoxicity and anti-colon cancer effects

The three-metallic oxide (Cu/Cr/Ni) nanoparticles were prepared using Echinops persicus plant extract via a simple, biocompatible, cost-effective, and non-toxic procedure, and their catalytic activity was evaluated over the synthesis of biologically activ

Environmentally Friendly Nafion-Mediated Friedl?nder Quinoline Synthesis under Microwave Irradiation: Application to One-Pot Synthesis of Substituted Quinolinyl Chalcones

An efficient and eco-friendly synthetic route for Friedl?nder quinoline synthesis of polysubstituted quinolines is described. This green chemical method starts from various 2-aminobenzophenones and mono- or dicarbonyl synthons and uses reusable Nafion NR50 material as a solid catalyst in ethanol under microwave irradiation. The protocol has a high generality of functional groups and provides the desired quinolines in good to excellent yields. Some structures were confirmed by single-crystal X-ray diffraction analysis.

Effective and Sustainable Access to Quinolines and Acridines: A Heterogeneous Imidazolium Salt Mediates C–C and C–N Bond Formation

Quinoline and acridine derivatives have been prepared using a functionalized imidazolium salt as heterogeneous catalyst. Different ketones have been coupled with 2-aminobenzaldehydes and 2-aminoaryl ketones under solvent-free conditions, employing 1,3-bis(carboxymethyl)-imidazolium chloride as a catalyst. The protocol is simple and effective for the synthesis of a variety of nitrogen containing heterocycles (> 35 examples) with moderate to excellent yields (up to 96 %), being possible to perform the reaction in preparative scale. Additionally, 3-acetylquinolines have been transformed, under solvent-free conditions, into quinolyl chalcone derivatives by means of the same catalyst. Thus, the catalytic system mediates both reactions effectively in a tandem procedure. Furthermore, the catalyst is easily separated from the reaction mixture and can be reused without loss of activity (up to 8 cycles) which remarks its sturdiness. The E-factors are in the range of 14–23, both for the formation of quinolines and for the tandem reaction, which demonstrates the sustainability of the protocols described.

Sulfamic acid supported on Fe3O4@SiO2superpara magnetic nanoparticles as a recyclable heterogeneous catalyst for the synthesis of quinolines

In the present study, for the first time the synthesis of sulfamic acid supported on Fe3O4@SiO2superpara magnetic nanoparticles as a solid acid catalyst with large density of sulfamic acid groups was suggested. The structu

Design, synthesis and evaluation of acridine and fused-quinoline derivatives as potential anti-tuberculosis agents

The synthesis of twelve acridine and polycyclic acridine derivatives prepared via the Friedl?nder reaction is described. The one-pot reactions of 2-amino-5-chloro or 5-nitro-benzophenones and a variety of cyclanones and indanones were carried out in a MW

An unprecedented tandem annulation of ω-azido-1-alkynes with diaryl-iodonium salts: A facile synthesis of polycyclic quinolines

Polysubstituted quinolines are synthesized through an unprecedented cascade annulation of ω-azido-1-alkynes with diaryliodonium salts, which serve as C2-building blocks. The reaction proceeds smoothly and is catalyzed by Cu(I) catalysts to give various qu

PEG-SO3H as a catalyst in aqueous media: A simple, proficient and green approach for the synthesis of quinoline derivatives

A convenient and efficient method was developed for the synthesis of quinolines, an important class of potentially bioactive compounds. The quinoline derivatives were prepared in water, an excellent solvent in terms of environmental impact and with reduce

1-butyl-3-methylimidazolium hydrogen sulfate ([bmim]-HSO 4)-mediated synthesis of polysubstituted quinolines

In this research, polysubstituted quinolines are prepared from the reaction of 2-aminobenzophenones and ethylacetoacetate or ketones in the presence of 1-butyl-3-methylimidazolium hydrogen sulfate [bmim]HSO4 as an acidic ionic liquid in good to

The first cerium (IV) ammonium nitrate (CAN)-catalyzed friedlaender synthesis of quinolines in ionic liquid

A mild and efficient route for the synthesis of quinolines and polycyclic quinolines utilizing cerium (IV) ammonium nitrate (CAN) as a novel catalyst via Friedlaender annulation in ionic liquid 1-n-butyl-3-methylimidazolium hexafluorophosphate [Bmim][PF6]