116939-11-8

Basic information

• Product Name: 2-AMino-N-(2,3-dihydro-benzo[1,4]dioxin-6-ylMethyl)-acetaMide
• Synonyms: 2-AMino-N-(2,3-dihydro-benzo[1,4]dioxin-6-ylMethyl)-acetaMide;5-(Chloromethyl)-2,3-dihydro-1,4-benzodioxin;5-(chloromethyl)-2,3-dihydro-1,4-benzodioxine
• CAS NO: 116939-11-8
• Molecular Formula: C11H14N2O3
• Molecular Weight: 222.24046
• Mol File: 116939-11-8.mol

Chemical Properties

• Boiling Point: 283.8±29.0 °C(Predicted)
• Appearance: /
• Density: 1.264±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-AMino-N-(2,3-dihydro-benzo[1,4]dioxin-6-ylMethyl)-acetaMide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMino-N-(2,3-dihydro-benzo[1,4]dioxin-6-ylMethyl)-acetaMide(116939-11-8)
• EPA Substance Registry System: 2-AMino-N-(2,3-dihydro-benzo[1,4]dioxin-6-ylMethyl)-acetaMide(116939-11-8)

Safety Data

• Hazardous Substances Data: 116939-11-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Drug Development:
2-Amino-N-(2,3-dihydro-benzo[1,4]dioxin-6-ylMethyl)-acetamide is used as a key intermediate in the synthesis of pharmaceutical drugs. Its unique structure allows for the development of new drug candidates with potential therapeutic effects.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 2-Amino-N-(2,3-dihydro-benzo[1,4]dioxin-6-ylMethyl)-acetamide is used as a research tool to study the structure-activity relationships of various biologically active compounds. This helps in understanding the molecular mechanisms of drug action and designing more effective drugs.
Used in Biochemical Pathway and Process Studies:
2-Amino-N-(2,3-dihydro-benzo[1,4]dioxin-6-ylMethyl)-acetamide is also used in the study of biochemical pathways and processes. Its potential biological activities make it a valuable compound for investigating the mechanisms of various biological processes and identifying new targets for drug development.
Used in Chemical, Biochemical, and Pharmaceutical Science:
Scientists and researchers in the fields of chemistry, biochemistry, and pharmaceutical science utilize 2-Amino-N-(2,3-dihydro-benzo[1,4]dioxin-6-ylMethyl)-acetamide for various purposes, including the development of new synthetic methods, understanding the properties of related compounds, and exploring its potential applications in drug discovery and development.

Upstream product

• 24677-78-9 2,3-dihydroxybenzaldehyde 
• 29668-43-7 2,3-dihydro-benzo[1,4]dioxine-5-carbaldehyde 
• 274910-19-9 (2,3-dihydrobenzo[b][1,4]dioxin-5-yl)methanol 
• 493-09-4 benzo-1,4-dioxane 
• 50-00-0 formaldehyd 

Downstream Products

• 274910-20-2 2-(2,3-dihydro-1,4-benzodioxin-5-yl)acetic acid 

Relevant articles and documents

Kinetics of Chloromethylation of Benzo-1,4-Dioxane

The chloromethylation of benzo-1,4-dioxane in acetic acid in presence of SnCl4, SbCl3, ZnCl2, and SbCl5 catalysts was investigated.The activation energy of the process was found to be 19.6 kcal/mole.The reaction is zero order in chloride ion and first order in the Hammet acidity function.In excess HCl the reaction is described by a second-order equation.The relative activities of the methyl chlorides in the chloromethylation of benzo-1,4-dioxane were determined.

PYRANOQUINAZOLINE DERIVATIVES AND NAPHTHOPYRAN DERIVATIVES

[Problem] A problem is presented in that conventional photochromic compounds cannot be considered adequate in terms of the colorizing/decolorizing rate and durability, and the production process therefore has many steps. The present invention provides an industrially applicable photochromic compound that has both a rapid colorizing/decolorizing reaction and high durability and can also be synthesized at a low cost. [Solution] This compound is characterized in that etheric oxygen atoms are bonded to the carbon atoms at position 1 of a pyranoquinazoline (8H-pyrano[3,2-f]quinazoline) skeleton and position 10 of a naphthopyran (3H-naphtho[2,1-b]pyran) skeleton, said compound having photochromic properties and being a photochromic compound that has both a rapid colorizing/decolorizing reaction and high durability. Also provided is an industrially applicable photochromic compound that can be synthesized at a low cost.

PURINE DERIVATIVES AS KINASE INHIBITORS

The present invention provides kinase inhibitors of Formula I.

N-ACYLAMINO ACID DERIVATIVES AND THEIR PHARMACEUTICAL COMPOSITIONS

An N-acylamino acid derivative of the formula: STR1 wherein the substituents are herein defined or a salt thereof, which is useful as hypotensive drugs.