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2-(2,2-Difluoro-cyclopropyl)-ethanol is a chemical compound characterized by its molecular formula C5H8F2O. It is a colorless liquid with a molecular weight of 130.11 g/mol. 2-(2,2-Difluoro-cyclopropyl)-ethanol is distinguished by its unique chemical structure and properties, which make it a valuable ingredient in the manufacturing of various chemical products.

117284-59-0

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117284-59-0 Usage

Uses

Used in Pharmaceutical Industry:
2-(2,2-Difluoro-cyclopropyl)-ethanol is utilized as a building block for the synthesis of various drugs and pharmaceutical products. Its unique structure and properties contribute to the development of new and innovative medications.
Used in Agrochemical Production:
In the agrochemical industry, 2-(2,2-Difluoro-cyclopropyl)-ethanol is employed in the production of various agrochemicals. Its specific chemical attributes make it suitable for the creation of effective and targeted agricultural products.
Used in Specialty Chemicals Manufacturing:
2-(2,2-Difluoro-cyclopropyl)-ethanol is also used in the manufacturing of specialty chemicals, where its distinct properties are leveraged to produce high-quality and specialized chemical products for various applications.
Safety Precautions:
It is important to handle 2-(2,2-Difluoro-cyclopropyl)-ethanol with care and follow proper safety precautions when working with it in a laboratory or industrial setting to ensure the safety of personnel and the integrity of the compound.

Check Digit Verification of cas no

The CAS Registry Mumber 117284-59-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,7,2,8 and 4 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 117284-59:
(8*1)+(7*1)+(6*7)+(5*2)+(4*8)+(3*4)+(2*5)+(1*9)=130
130 % 10 = 0
So 117284-59-0 is a valid CAS Registry Number.

117284-59-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(2,2-Difluorocyclopropyl)ethanol

1.2 Other means of identification

Product number -
Other names Cyclopropaneethanol,2,2-difluoro

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:117284-59-0 SDS

117284-59-0Relevant articles and documents

Rate constant for the ring opening of the 2,2-difluorocyclopropylcarbinyl radical

Tian, Feng,Dolbier Jr., William R.

, p. 835 - 837 (2000)

(figure presented) The rate constant for the unimolecular ring opening of the 2,2-difluorocyclopropylcarbinyl radical was determined via its competitive bimolecular trapping by TEMPO. The value of this rate constant (3.4 × 1011 s-1 a

FLUORINE-CONTAINING TRIAZOLOPYRIDINE, AND MANUFACTURING METHOD, PHARMACEUTICAL COMPOSITION, AND APPLICATION THEREOF

-

Paragraph 0076, (2019/04/16)

The present invention provides a fluorine-containing triazolopyridine represented by formula (I) and a racemate, R-stereoisomer, S-stereoisomer, pharmaceutically acceptable salt, or mixture thereof. The triazolopyridine can be used as a positive allosteri

Synthesis of Functionalized Difluorocyclopropanes: Unique Building Blocks for Drug Discovery

Bychek, Roman M.,Levterov, Vadym V.,Sadkova, Iryna V.,Tolmachev, Andrey A.,Mykhailiuk, Pavel K.

supporting information, p. 12291 - 12297 (2018/03/28)

Difluorocyclopropane-containing building blocks for drug discovery were synthesized from the functionalized alkenes and TMSCF3/NaI. Novel fluorinated acids, amines, amino acids, alcohols, ketones and sulfonyl chlorides were obtained.

POLYCYCLIC TLR7/8 ANTAGONISTS AND USE THEREOF IN THE TREATMENT OF IMMUNE DISORDERS

-

Paragraph 00781, (2017/07/06)

The present invention relates to compounds of Formula (I) and pharmaceutically acceptable compositions thereof, useful as toll-like receptor 7/8 (TLR7/8) antagonists. In Formula (I), Ring A is aryl or heteroaryl; Ring B is aryl or heteroary; and X is C(R4)2, O, NR4, S, S(R4), or S(R4)2.

PIPERIDINE-DIONE DERIVATIVES

-

Page/Page column 113; 114, (2015/11/10)

The invention provides novel compounds having the general formula (I) and tautomers and pharmaceutically acceptable salts thereof, wherein A1, A2, A3, A4, R1, R4, R5, R6, R7 and R8 are as defined herein, compositions including the compounds and methods of using the compounds.

METHOD OF CONTROLLING LACTATE PRODUCTION WITH PIPERDINE-DIONE DERIVATIVES

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Page/Page column 101, (2015/11/10)

The invention provides novel compounds having the general formula: and tautomers and pharmaceutically acceptable salts thereof, wherein A1, A2, A3, A4, R1, R4, R5, R6, R7 and R8 are as defined herein, compositions including the compounds and methods of using the compounds.

Hepatitis C virus NS3-4A serine protease inhibitors: SAR of new P1 derivatives of SCH 503034

Bogen,Arasappan,Pan,Ruan,Padilla,Saksena,Girijavallabhan,Njoroge

scheme or table, p. 4219 - 4223 (2009/04/07)

Substitutions on the P1 cyclobutyl side chain of SCH 503034 were studied by introduction of hydroxyl and fluoro substituents. Additionally, effects of fluoro substitution on other P1 moieties were evaluated.

2-(2,2-Difluorocyclopropyl)alkyl esters, processes for their preparation and their use as insecticides and acaricides

-

, (2008/06/13)

There are provided new 2-(2,2-difluorocyclopropyl)alkyl esters of general formula I STR1 in which Y, R1-7 and n have the meanings given in the description and processes for their preparation. The new compounds can be used to combat insects and

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