117833-60-0

Basic information

• Product Name: a-Bromo-N-Boc-Gly-OtBu
• Synonyms: a-Bromo-N-Boc-Gly-OtBu;Alfa-Bromo-N-Boc-Gly-OtBu;Acetic acid,2-broMo-2-[[(1,1-diMethylethoxy)carbonyl]aMino]-, 1,1-diMethylethyl ester;broMo(tert-butoxycarbonylaMino)acetic acid tert-butyl ester;tert-Butyl 2-bromo-2-((tert-butoxycarbonyl);tert-butyl 2-bromo-2-[(2-methylpropan-2-yl)oxycarbonylamino]acetate
• CAS NO: 117833-60-0
• Molecular Formula: C₁₁H₂₀BrNO₄
• Molecular Weight: 310.1848
• Mol File: 117833-60-0.mol

Chemical Properties

• Melting Point: 55℃
• Boiling Point: 337.8±32.0 °C(Predicted)
• Appearance: /
• Density: 1.294±0.06 g/cm3(Predicted)
• PKA: 9.16±0.46(Predicted)
• CAS DataBase Reference: a-Bromo-N-Boc-Gly-OtBu(CAS DataBase Reference)
• NIST Chemistry Reference: a-Bromo-N-Boc-Gly-OtBu(117833-60-0)
• EPA Substance Registry System: a-Bromo-N-Boc-Gly-OtBu(117833-60-0)

Safety Data

• Hazardous Substances Data: 117833-60-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
a-Bromo-N-Boc-Gly-OtBu is used as a key intermediate for the synthesis of various pharmaceuticals and biologically active compounds. The Boc protecting group allows for selective manipulation of the amino group, facilitating the synthesis of complex organic molecules with specific biological activities.
Used in Peptide Synthesis:
In the field of peptide synthesis, a-Bromo-N-Boc-Gly-OtBu is utilized as a building block for the preparation of peptides with desired sequences and functions. The Boc group provides protection to the amino group, enabling the stepwise assembly of peptide chains through selective coupling reactions.
Used in Organic Synthesis:
a-Bromo-N-Boc-Gly-OtBu is employed as a versatile building block in organic synthesis for the preparation of a wide variety of complex organic molecules. The alpha-bromo substitution enhances the reactivity of the compound, allowing for efficient transformations and functional group manipulations in the synthesis of target molecules.

Upstream product

• 27532-96-3 glycine tert-butyl ester hydrochloride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 111652-20-1 N-(tert-butoxycarbonyl)glycine tert-butyl ester 

Downstream Products

• 111717-08-9 t-butyl 2-(t-butoxycarbonylamino)-4-oxo-4-phenylbutanoate 
• 111652-16-5 (S)-tert-Butoxycarbonylamino-((S)-2-oxo-cyclohexyl)-acetic acid tert-butyl ester 
• 111652-11-0 tert-Butoxycarbonylamino-p-tolyl-acetic acid tert-butyl ester 
• 111652-10-9 tert-Butoxycarbonylamino-phenyl-acetic acid tert-butyl ester 
• 111652-08-5 2-tert-Butoxycarbonylamino-4-phenyl-butyric acid tert-butyl ester 
• 111652-12-1 tert-Butoxycarbonylamino-(4-methoxy-phenyl)-acetic acid tert-butyl ester 
• 119768-66-0 t-butyl 2-(t-butoxycarbonylamino)-4-oxo-3-(oxophenylmethyl)pentanoate 
• 119768-56-8 t-butyl 2-(t-butoxycarbonylamino)-2-(1-hydroxy-5,5-dimethyl-3-oxocyclohexen-2-yl)acetate 

Relevant articles and documents

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