111652-10-9

Basic information

• Product Name: tert-Butoxycarbonylamino-phenyl-acetic acid tert-butyl ester
• Synonyms: tert-Butoxycarbonylamino-phenyl-acetic acid tert-butyl ester
• CAS NO: 111652-10-9
• Molecular Weight: 307.39
• Mol File: 111652-10-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: tert-Butoxycarbonylamino-phenyl-acetic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butoxycarbonylamino-phenyl-acetic acid tert-butyl ester(111652-10-9)
• EPA Substance Registry System: tert-Butoxycarbonylamino-phenyl-acetic acid tert-butyl ester(111652-10-9)

Safety Data

• Hazardous Substances Data: 111652-10-9(Hazardous Substances Data)

Upstream product

• 109774-57-4 N,N-bis(tert-butoxycarbonyl)benzylamine 
• 4248-19-5 tert-butyl carbazate 
• 72410-67-4 tert-butyl 2-diazo-2-phenylacetate 
• 117833-60-0 N-tert-butoxycarbonyl-α-bromoglycine tert-butyl ester 
• 111652-20-1 N-(tert-butoxycarbonyl)glycine tert-butyl ester 
• 27532-96-3 glycine tert-butyl ester hydrochloride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 111652-21-2 t-Butyl N-(butoxycarbonyl)iminoacetate 
• 2900-27-8 2-(tert-butoxycarbonylamino)-2-phenylacetic acid 
• 75-65-0 tert-butyl alcohol 

Downstream Products

• 71849-99-5 (+/-)-α-phenylglycine hydrochloride 

Relevant articles and documents

A novel, general route to the synthesis of carboxylic acid esters and thiolesters

Carboxylic acids were conveniently esterified with alcohols and thiols by the use of triphenylphosphine and N-bromo/Iodo succinimide to afford the corresponding esters and thiol esters.

A convenient synthesis of N-Boc-protected tert-butyl esters of phenylglycines from benzylamines

The N,N-di-Boc-protected benzylamines undergo [1,2] Boc migration on treatment with KDA/t-BuOLi. By this reaction, the corresponding N-Boc-protected t-butyl esters of phenylglycines are obtained in high yields.