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2-(2-aMino-5-broMophenyl)-2-oxoacetic acid is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 120095-19-4 Structure
  • Basic information

    1. Product Name: 2-(2-aMino-5-broMophenyl)-2-oxoacetic acid
    2. Synonyms: 2-(2-aMino-5-broMophenyl)-2-oxoacetic acid;potassiuM 2-(2-aMino-5-broMophenyl)-2-oxoacetate;Potassium 2-(2-amino-5-bromophenyl)
    3. CAS NO:120095-19-4
    4. Molecular Formula: C8H5BrNO3*K
    5. Molecular Weight: 244.04214
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 120095-19-4.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-(2-aMino-5-broMophenyl)-2-oxoacetic acid(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-(2-aMino-5-broMophenyl)-2-oxoacetic acid(120095-19-4)
    11. EPA Substance Registry System: 2-(2-aMino-5-broMophenyl)-2-oxoacetic acid(120095-19-4)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 120095-19-4(Hazardous Substances Data)

120095-19-4 Usage

Chemical Class

The compound belongs to the class of organic compounds known as phenylpyruvic acids.

Formation

It is formed by the condensation of 2-oxoacetic acid with 2-amino-5-bromophenylamine.

Derivative

It is a derivative of phenylpyruvic acid, which is a key intermediate in the phenylalanine metabolic pathway.

Role in Metabolism

It plays a role in the conversion of phenylalanine to tyrosine, an essential amino acid.

Research and Biochemical Studies

It can be used in research and biochemical studies related to metabolism and amino acid synthesis.

Check Digit Verification of cas no

The CAS Registry Mumber 120095-19-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,0,0,9 and 5 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 120095-19:
(8*1)+(7*2)+(6*0)+(5*0)+(4*9)+(3*5)+(2*1)+(1*9)=84
84 % 10 = 4
So 120095-19-4 is a valid CAS Registry Number.

120095-19-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name potassium,2-(2-amino-5-bromophenyl)-2-oxoacetate

1.2 Other means of identification

Product number -
Other names (2-amino-5-bromo-phenyl)-glyoxylic acid,potassium salt

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:120095-19-4 SDS

120095-19-4Relevant articles and documents

Fragment-Based Discovery of 5-Arylisatin-Based Inhibitors of Matrix Metalloproteinases 2 and 13

Agamennone, Mariangela,Belov, Dmitry S.,Laghezza, Antonio,Ivanov, Vladimir N.,Novoselov, Anton M.,Andreev, Ivan A.,Ratmanova, Nina K.,Altieri, Andrea,Tortorella, Paolo,Kurkin, Alexander V.

supporting information, p. 1892 - 1898 (2016/10/06)

Matrix metalloproteinases (MMPs) are well-established targets for several pathologies. In particular, MMP-2 and MMP-13 play a prominent role in cancer progression. In this study, a structure-based screening campaign was applied to prioritize metalloproteinase-oriented fragments. This computational model was applied to a representative fragment set from the publically available EDASA Scientific compound library. These fragments were prioritized, and the top-ranking hits were tested in a biological assay to validate the model. Two scaffolds showed consistent activity in the assay, and the isatin-based compounds were the most interesting. These latter fragments have significant potential as tools for the design and realization of novel MMP inhibitors. In addition to their micromolar activity, the chemical synthesis affords flexible and creative access to their analogues.

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