121056-95-9Relevant articles and documents
Synthesis of the octahydroindole unit of aeruginosins via asymmetric hydrogenation of the Diels-Alder adducts of 2-amido-2,4-pentadienoate
Hoshina, Yoichiro,Doi, Takayuki,Takahashi, Takashi
, p. 12740 - 12746 (2007)
An optically active octahydroindole, the core unit of aeruginosins (Choi) was synthesized. The Diels-Alder reaction of Danishefsky's diene with methyl (Z)-2-acetamido-2,4-pentadienoates provided the adducts regioselectively in good yield. The adducts were
Preparation method of Wittig-Horner reagent
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Paragraph 0030-0032; 0041-0042, (2021/07/31)
A preparation method of a Wittig-Horner reagent is disclosed. According to the preparation method of the Wittig-Horner reagent provided by the invention, a compound with a structure as shown in a formula (I) and a glyoxylic acid aqueous solution with a sp
SYNTHESIS OF (S)-6-HYDROXYTRYPTOPHAN AND DERIVATIVES THEREOF
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, (2020/07/07)
The present invention relates to novel methods and compounds for synthesizing amanitin derivatives. The invention in particular relates to methods for synthesizing (S)-6-hydroxy-tryptophan derivatives which can be used as building blocks for synthesizing
PEPTIDE NUCLEIC ACID MONOMERS AND OLIGOMERS
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, (2017/07/06)
The invention relates to new peptide nucleic acid monomers and peptide nucleic acid oligomers comprising a dialkylamine side chain substituted with phosphonic acid ester group(s) or phosphonic acid group(s), and to the uses thereof.
A new convenient synthesis of N-acyl-2-(dimethoxyphosphoryl)glycinates
Mazurkiewicz, Roman,Ku?nik, Anna
, p. 3439 - 3442 (2007/10/03)
Easily accessible N-acyl-2-triphenylphosphonioglycinate tetrafluoroborates react smoothly with trimethylphosphite in the presence of methyltriphenylphosphonium iodide to give N-acyl-2-(dimethoxyphosphoryl)glycinates in good or very good yields. The dimeth
METHODS OF PREPARATION OF DEHYDRO-DIKETOPIPERAZINES IN LIQUID PHASE OR OF SOLID SUPPORTED PHASE
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Page 7, (2008/06/13)
The preparation of any compound of the generic structure (I); wherein: R1 and R2 are substituents described in the main text. Cycl- is a group represented by either of the formulae (a) and (b); wherein: R3 to R8
Total synthesis of isoroquefortine C
Schiavi, Bruno M.,Richard, David J.,Joullie, Madeleine M.
, p. 620 - 624 (2007/10/03)
A short and efficient total synthesis of isoroquefortine C, the 3,12-(Z)-isomer of roquefortine C, from L-tryptophan methyl ester hydrochloride and 4(5)-(hydroxy)methylimidazole hydrochloride is described.
Carbacyclic peptide mimetics as VCAM-VLA-4 antagonists
Tilley, Jefferson,Kaplan, Gerry,Fotouhi, Nader,Wolitzky, Barry,Rowan, Karen
, p. 1163 - 1165 (2007/10/03)
Substitution of carbon for sulfur in a potent 13-membered cyclic disulfide containing peptide was accomplished via an intramolecular Wittig reaction and resulted in a series of 'carba' analogues. Potency in the VCAM-VLA-4 assay was sensitive to ring size and lower than that of the parent disulfide. (C) 2000 Elsevier Science Ltd. All rights reserved.
Synthesis of non-natural O-glycosylamino acids derived from n-pentenyl glycosides; model studies and proof of principle for glycopeptide synthesis
Allen, Jennifer R.,Danishefsky, Samuel J.
, p. 736 - 744 (2007/10/03)
Model studies on the transformation of the olefinic unit contained in n-pentenyl glycosides (NPGs) to glycoamino acids is described. The methodology involves a Horner-Emmons olefination with a protected glycine derived phosphonate, followed by asymmetric