Welcome to LookChem.com Sign In|Join Free

CAS

  • or
7H-Pyrrolo[2,3-d]pyrimidine-6-carboxamide, 2-chloro-7-cyclopentyl-N,N-dimethyl, is a chemical compound with the molecular formula C14H17ClN4O. It is a derivative of pyrrolopyrimidine, specifically substituted with a chlorine atom at the 2-position and a cyclopentyl and two methyl groups at the 7-position. 7H-Pyrrolo[2,3-d]pyriMidine-6-carboxaMide, 2-chloro-7-cyclopentyl-N,N-diMethylpossesses potential pharmacological activities and is valuable for research purposes in the pharmaceutical industry. Its unique structure allows it to interact with various biological targets and pathways, making it a promising candidate for further study and potential therapeutic applications.

1211443-61-6 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid dimethylamide

    Cas No: 1211443-61-6

  • USD $ 1.2-5.0 / Kiloliter

  • 5 Kiloliter

  • 3000 Metric Ton/Month

  • Chemwill Asia Co., Ltd.
  • Contact Supplier
  • 1211443-61-6 Structure
  • Basic information

    1. Product Name: 7H-Pyrrolo[2,3-d]pyriMidine-6-carboxaMide, 2-chloro-7-cyclopentyl-N,N-diMethyl-
    2. Synonyms: 7H-Pyrrolo[2,3-d]pyriMidine-6-carboxaMide, 2-chloro-7-cyclopentyl-N,N-diMethyl-;2-chloro-7-cyclopentyl-N,N-diMethyl-7H-pyrrolo[2,3-d]pyriMidine-6-carboxaMide;RIBOCICLIB INT;Ribociclib-1;7H-Pyrrolo[2,3-d]pyrimidine-6-carboxamide;2-chloro-7-cyclopentyl-N,N-diMethyl-7H-pyrrolo[2,3-d]pyriMidine-6-arboxaMide;2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid dimethylamide;EOS-60967
    3. CAS NO:1211443-61-6
    4. Molecular Formula: C14H17ClN4O
    5. Molecular Weight: 292.76398
    6. EINECS: 1592732-453-0
    7. Product Categories: N/A
    8. Mol File: 1211443-61-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.40±0.1 g/cm3(Predicted)
    6. Vapor Pressure: 0-0Pa at 20-25℃
    7. Refractive Index: N/A
    8. Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
    9. Solubility: N/A
    10. PKA: 2.78±0.30(Predicted)
    11. CAS DataBase Reference: 7H-Pyrrolo[2,3-d]pyriMidine-6-carboxaMide, 2-chloro-7-cyclopentyl-N,N-diMethyl-(CAS DataBase Reference)
    12. NIST Chemistry Reference: 7H-Pyrrolo[2,3-d]pyriMidine-6-carboxaMide, 2-chloro-7-cyclopentyl-N,N-diMethyl-(1211443-61-6)
    13. EPA Substance Registry System: 7H-Pyrrolo[2,3-d]pyriMidine-6-carboxaMide, 2-chloro-7-cyclopentyl-N,N-diMethyl-(1211443-61-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1211443-61-6(Hazardous Substances Data)

1211443-61-6 Usage

Uses

Used in Pharmaceutical Research:
7H-Pyrrolo[2,3-d]pyrimidine-6-carboxamide, 2-chloro-7-cyclopentyl-N,N-dimethyl, is used as a research compound for exploring its pharmacological properties and potential therapeutic applications. Its unique structure and interactions with biological targets make it a valuable tool for understanding various disease mechanisms and developing novel treatment strategies.
Used in Drug Discovery and Development:
In the drug discovery and development industry, 7H-Pyrrolo[2,3-d]pyrimidine-6-carboxamide, 2-chloro-7-cyclopentyl-N,N-dimethyl, is utilized as a lead compound for the identification and optimization of new drug candidates. Its potential pharmacological activities and interactions with biological targets can guide the design and synthesis of more effective and selective therapeutic agents.
Used in Chemical Synthesis:
7H-Pyrrolo[2,3-d]pyrimidine-6-carboxamide, 2-chloro-7-cyclopentyl-N,N-dimethyl, can also be used as a starting material or intermediate in the synthesis of other related compounds with potential applications in various fields, such as pharmaceuticals, agrochemicals, or materials science.

Check Digit Verification of cas no

The CAS Registry Mumber 1211443-61-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,1,1,4,4 and 3 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1211443-61:
(9*1)+(8*2)+(7*1)+(6*1)+(5*4)+(4*4)+(3*3)+(2*6)+(1*1)=96
96 % 10 = 6
So 1211443-61-6 is a valid CAS Registry Number.

1211443-61-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid dimethylamide

1.2 Other means of identification

Product number -
Other names 2-chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1211443-61-6 SDS

1211443-61-6Relevant articles and documents

Synthesis method of ribociclib intermediate product and intermediate compound thereof

-

Paragraph 0089-0091, (2020/05/14)

The invention discloses a synthesis method of a ribociclib intermediate product, which comprises the following steps: by using barbituric acid as a starting material, carrying out chlorination and formylation to obtain a compound 2; and performing condens

POLYMORPHS OF 7-CYCLOPENTYL-N,N-DIMETHYL-2-{[5-(PIPERAZIN-1-YL) PYRIDIN-2-YL]-AMINO}-7H-PYRROLO[2,3-D]PYRIMIDINE-6-CARBOXAMIDE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS AND PROCESS FOR THE PREPARATION THEREOF

-

Page/Page column 25-27, (2020/11/12)

The present invention relates to novel crystalline forms of butanedioic acid 7-cyclopentyl-N,N-dimethyl-2-{[5-(piperazin-1-yl) pyridin-2-yl]amino}-7H-pyrrolo[2,3-d] pyrimidine-6-carboxamide of formula-1a and process for preparation thereof. The present invention also relates to a process for the preparation of 7-cyclopentyl-N,N-dimethyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H-pyrrolo[2,3-d] pyrimidine-6-carboxamide. Further, the present application also relates to acid addition salts of 7-cyclopentyl-N,N-dimethyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H-pyrrolo[2,3-d] pyrimidine-6-carboxamide and process for the preparation thereof.

CDK9 inhibitor, preparation method and application thereof

-

Paragraph 0106-0107; 0115-0116, (2021/01/04)

The invention provides a CDK9 inhibitor, the CDK9 inhibitor is a pyrimidopyrrole kinase inhibitor, and the chemical structural general formula of the CDK9 inhibitor is shown as the formula I in the specification, the CDK9 inhibitor is the pyrimidopyrrole kinase inhibitor, the protein target adapted to the pyrimidopyrrole kinase is serine/threonine kinase CDK9. The CDK9 inhibitor shows relatively high specificity and low cytotoxicity, and the CDK9 inhibitor which is used for preventing or treating tumor growth and metastasis, has selectivity on CDK9, and is small in toxic and side effects and strong in action effect is provided, so that the CDK9 inhibitor is used for regulating and controlling the biological function of CDK9 and inhibiting the growth and proliferation processes of tumors.

AN IMPROVED PROCESS FOR THE PREPARATION OF RIBOCICLIB SUCCINATE AND ITS NOVEL CRYSTALLINE FORMS THEREOF

-

Page/Page column 19-20, (2019/08/08)

The present invention relates to an improved process for the preparation of 7-cyclopentyl-N,N-dimethyl-2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide succinate (1/1) compound of formula-1a and its novel crystalline for

Key intermediate for synthesis of CDK 4/6 dual inhibitor and preparation method and application of key intermediate

-

Paragraph 0119; 0122-0125; 0128-0131; 0134-0137; 0141-0143, (2019/08/20)

The invention discloses a 2-chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-methanamide intermediate and a preparation method and application thereof. The intermediate is the compoundI, and the preparation method comprises the following st

Synthesis method of antineoplastic drug ribociclib intermediate

-

Paragraph 0032; 0061-0078, (2019/11/13)

The invention relates to a synthesis method of an antineoplastic drug ribociclib intermediate. The synthesis method includes the following steps that the electrophilic addition reaction is conducted on N,N-dimethylacrylamide and bromine to obtain N,N-dime

Synthesis method of anti-tumor drug ribociclib

-

Paragraph 0041; 0081-0098, (2019/11/14)

The invention relates to a synthesis method of an anti-tumor drug ribociclib. The method mainly comprises the steps of carrying out a reaction between 4-(6-amino-3-pyridyl)-1-piperazinyl tert-butyl formate and 2-chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrol

SUBSTITUTED PYRROLOPYRIMIDINE CDK INHIBITOR, PHARMACEUTICAL COMPOSITION CONTAINING SAME AND USE THEREOF

-

Paragraph 0109; 0114; 0115, (2019/02/09)

The present invention belongs to the field of pharmaceutical chemistry, and relates to a substituted pyrrolopyrimidine CDK inhibitor, in particular to a compound as shown in formula I or a pharmaceutically acceptable salt or solvate thereof, as well as a preparation method thereof and a pharmaceutical composition thereof. The present invention also relates to the use of the compound and the pharmaceutical composition thereof in the preparation of a drug for treating diseases associated with CDK inhibition. The compound according to the present invention has a marked inhibitory effect on CDK, excellent drug absorption and significantly superior oral absorption effect.

New intermediate of ribociclib, and synthetic method for preparing ribociclib by using new intermediate

-

Paragraph 0098; 0099, (2018/10/19)

The invention provides a new intermediate compound 6 of ribociclib, and a preparation method thereof, and a synthetic method for preparing ribociclib by using the new intermediate compound 6, whereinthe structure of the compound 6 is defined in the specif

THIENOPYRANONES AND FURANOPYRANONES AS KINASE, BROMODOMAIN, AND CHECKPOINT INHIBITORS

-

Paragraph 0218, (2018/08/20)

The invention relates to compounds and methods of treating diseases including but not limited to, cancer, non-cancer proliferative disease, sepsis, autoimmune disease, viral infaction, atheroscleosis. Type 1 or 2 diabetes, obesity, inflammatory disease, o

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 1211443-61-6