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3'-Fluoro-3'-deoxycytidine, also known as 3'-Deoxy-3'-fluorocytidine, is a cytidine derivative that exhibits minor antiviral and cytostatic properties. It is a modified nucleoside with a fluorine atom at the 3' position, which contributes to its unique biological activity.

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    Cas No: 123402-20-0

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  • 123402-20-0 Structure
  • Basic information

    1. Product Name: 3'-Fluoro-3'-deoxycytidine
    2. Synonyms: 3'-Fluoro-3'-deoxycytidine;3'-F-3'-Dc;3'-Deoxy-3'-fluorocytidine, Antiviral agent;4-amino-1-[(2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
    3. CAS NO:123402-20-0
    4. Molecular Formula: C9H12FN3O4
    5. Molecular Weight: 245.2076832
    6. EINECS: 200-001-2
    7. Product Categories: N/A
    8. Mol File: 123402-20-0.mol
  • Chemical Properties

    1. Melting Point: 221-223 °C
    2. Boiling Point: 500.1°Cat760mmHg
    3. Flash Point: 256.2°C
    4. Appearance: /
    5. Density: 1.82g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. PKA: 12.81±0.70(Predicted)
    10. CAS DataBase Reference: 3'-Fluoro-3'-deoxycytidine(CAS DataBase Reference)
    11. NIST Chemistry Reference: 3'-Fluoro-3'-deoxycytidine(123402-20-0)
    12. EPA Substance Registry System: 3'-Fluoro-3'-deoxycytidine(123402-20-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 123402-20-0(Hazardous Substances Data)

123402-20-0 Usage

Uses

Used in Antiviral Applications:
3'-Fluoro-3'-deoxycytidine is used as an antiviral agent for its ability to inhibit viral replication and reduce the severity of viral infections. Its cytostatic properties also contribute to limiting the spread of viruses within the host.
Used in Cytostatic Applications:
In the field of cancer research and treatment, 3'-Fluoro-3'-deoxycytidine is used as a cytostatic agent to slow down the growth and proliferation of cancer cells. This can be beneficial in managing the progression of certain types of cancer and potentially improving patient outcomes.
Used in Pharmaceutical Industry:
3'-Fluoro-3'-deoxycytidine is utilized in the pharmaceutical industry as a key intermediate in the synthesis of more potent antiviral and cytostatic drugs. Its unique structure allows for the development of novel therapeutic agents with improved efficacy and reduced side effects.
Used in Research and Development:
3'-Fluoro-3'-deoxycytidine serves as an important compound in research and development for understanding the mechanisms of viral replication and cancer cell growth. It can be used to study the effects of nucleoside analogs on cellular processes and to develop new strategies for combating viral infections and cancer.

Check Digit Verification of cas no

The CAS Registry Mumber 123402-20-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,3,4,0 and 2 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 123402-20:
(8*1)+(7*2)+(6*3)+(5*4)+(4*0)+(3*2)+(2*2)+(1*0)=70
70 % 10 = 0
So 123402-20-0 is a valid CAS Registry Number.

123402-20-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-amino-1-[(2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

1.2 Other means of identification

Product number -
Other names 3'-deoxy-3'-fluorocytidine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:123402-20-0 SDS

123402-20-0Downstream Products

123402-20-0Relevant articles and documents

Synthesis and antiviral and cytostatic properties of 3'-deoxy-3'-fluoro- and 2'-azido-3'-fluoro-2',3'-dideoxy-D-ribofuranosides of natural heterocyclic bases

Mikhailopulo,Poopeiko,Pricota,Sivets,Kvasyuk,Balzarini,De Clercq

, p. 2195 - 2202 (2007/10/02)

A series of 3'-deoxy-3'-fluoro- and 2'-azido-2',3'-dideoxy-3'-fluoro-D-ribofuranosides of natural heterocyclic bases have been synthesized with the use of universal carbohydrate precursors, viz., 1-O-acetyl-2,5-di-O-benzoyl-3-deoxy-3-fluoro-D-ribofuranose

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