126264-49-1

Basic information

• Product Name: 3-MORPHOLINECARBOXYLIC ACID METHYL ESTER
• Synonyms: METHYL MORPHOLINE-3-CARBOXYLATE;3-MORPHOLINECARBOXYLIC ACID METHYL ESTER;3-Morpholinecarboxylicacid,methylester(9CI);3-MORPHOLINECARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE;3-Morpholinecarboxylic acid methyl ester HCl;Methyl 3-Morpholinecarboxylate;methyl morpholine-3-carboxylate hydrochloride
• CAS NO: 126264-49-1
• Molecular Formula: C₆H₁₁NO₃
• Molecular Weight: 145.16
• EINECS: 242-641-0
• Product Categories: CARBOXYLICESTER;pharmacetical
• Mol File: 126264-49-1.mol

Chemical Properties

• Boiling Point: 202.2 °C at 760 mmHg
• Flash Point: 76.1 °C
• Appearance: /
• Density: 1.106 g/cm³
• Vapor Pressure: 0.295mmHg at 25°C
• Refractive Index: 1.436
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• PKA: 6.96±0.40(Predicted)
• CAS DataBase Reference: 3-MORPHOLINECARBOXYLIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3-MORPHOLINECARBOXYLIC ACID METHYL ESTER(126264-49-1)
• EPA Substance Registry System: 3-MORPHOLINECARBOXYLIC ACID METHYL ESTER(126264-49-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22-51
• Hazardous Substances Data: 126264-49-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Synthesis:
3-Morpholinecarboxylic Acid Methyl Ester is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique chemical structure allows it to be a valuable building block for the development of new drugs, contributing to the advancement of medicine.
Used in Coatings Industry:
In the coatings industry, 3-Morpholinecarboxylic Acid Methyl Ester is used as an emulsifier. Its polar nature enables it to improve the stability and performance of coating formulations, ensuring a uniform distribution of ingredients and enhancing the final product's quality.
Used in Pesticides:
3-Morpholinecarboxylic Acid Methyl Ester is employed as an emulsifier in the formulation of pesticides. Its ability to stabilize mixtures helps in creating effective and long-lasting pest control solutions, contributing to agricultural productivity and food security.
Used in Cosmetic Products:
In the cosmetic industry, 3-Morpholinecarboxylic Acid Methyl Ester is used as an emulsifier to create stable and consistent formulations. Its polar properties allow for the even distribution of active ingredients, ensuring the effectiveness and safety of cosmetic products.

InChI:InChI=1/C6H11NO3/c1-9-6(8)5-4-10-3-2-7-5/h5,7H,2-4H2,1H3

Upstream product

• 67-56-1 methanol 
• 66937-99-3 morpholine-3-carboxylic acid hydrochloride 

Downstream Products

• 212650-45-8 morpholine-3,4-dicarboxylic acid 4-tert-butyl ester 3-methyl ester 
• 1101987-05-6 N,N-dimethylmorpholine-3-carboxamide 
• 212650-43-6 4-(tert-butoxycarbonyl)morpholine-3-carboxylic acid 
• 1571213-34-7 methyl 4-((6-(2-bromo-4-fluorophenyl)-5-(ethoxycarbonyl)-2-(thiazol-2-yl)-3,6-dihydropyrimidin-4-yl)methyl)morpholine-3-carboxylate 
• 285559-77-5 4-(2-nitrobenzoyl)morpholine-3-carboxylic acid methyl ester 

Relevant articles and documents

Synthesis of 3-oxadiazolyl/triazolyl morpholines: Novel scaffolds for drug discovery

Synthesis of isomeric 3-oxadiazolyl/triazolyl morpholines was performed based on a common intermediate on the gram scale. The target compounds were designed as novel scaffolds for the medicinal chemistry. The key reaction was an electrochemical CH-oxidati

Morpholine derivatives, pharmaceutical compositions and use

Compounds are disclosed of formula (I): STR1 wherein R1 and R2 are the same or different and are C1-6 alkyl or C3-6 alkenyl; or --NR1 R2 forms a 5-membered (optionally containing an oxygen