Abstract: A new efficient one-pot procedure has been developed for the synthesis of 1-substituted partially hydrogenated 3-oxocycloalka[c]pyridine-4-carbonitriles by reaction of cyclopentanone or cyclohexanone with morpholine, acyl chloride, and cyanoacetamide. The proposed procedure is advantageous due to shorter reaction time and smaller amounts of the solvents and reactants.
Geronikaki, A.,Hakobyan, E. K.,Hovakimyan, A. A.,Kartsev, V. G.,Sirakanyan, S. N.
p. 1748 - 1752
(2021/12/13)
SYNTHESIS OF SOME NEW FUSED THIENO- AND FUROPYRIDINES
Pyridone and thiopyridone derivatives (1) and (2) were considered as versatile intermediates to produce some interesting tricyclic compounds.They were converted to O- and S- alkylated pyridines (3) and (4) which undergo cycloaddition reaction to give the
Kamal El-Dean, A. M.,Abdel Hafez, A. A.,Attallah, A. A.
p. 1 - 6
(2007/10/02)
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