Welcome to LookChem.com Sign In|Join Free

CAS

  • or
2,N-DIMETHOXY-N-METHYLBENZAMIDE is a substituted benzamide derivative featuring two methoxy groups on the phenyl ring and a methyl group attached to the amide nitrogen. It is a versatile chemical compound that serves as a building block in organic synthesis and pharmaceutical research, with potential applications in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds.

130250-62-3 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 130250-62-3 Structure
  • Basic information

    1. Product Name: 2,N-DIMETHOXY-N-METHYLBENZAMIDE
    2. Synonyms: 2,N-DIMETHOXY-N-METHYLBENZAMIDE;N-2-DiMethoxy-N-MethylbenzaMide;2-Methoxy-N-Methoxy-N-MethylbenzaMide
    3. CAS NO:130250-62-3
    4. Molecular Formula: C10H13NO3
    5. Molecular Weight: 195.22
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 130250-62-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2,N-DIMETHOXY-N-METHYLBENZAMIDE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2,N-DIMETHOXY-N-METHYLBENZAMIDE(130250-62-3)
    11. EPA Substance Registry System: 2,N-DIMETHOXY-N-METHYLBENZAMIDE(130250-62-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 130250-62-3(Hazardous Substances Data)

130250-62-3 Usage

Uses

Used in Pharmaceutical Research and Organic Synthesis:
2,N-DIMETHOXY-N-METHYLBENZAMIDE is used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals for its potential to contribute to the development of new drugs and chemical products.
Used in Chemical Reactions:
2,N-DIMETHOXY-N-METHYLBENZAMIDE is used as a reagent in various chemical reactions, facilitating the synthesis of complex organic molecules and contributing to the advancement of chemical research.
Used in Material Science and Polymer Chemistry:
2,N-DIMETHOXY-N-METHYLBENZAMIDE is used as a potential component in material science and polymer chemistry, where it may contribute to the development of new materials with specific properties and applications.
Used in Biological Research:
2,N-DIMETHOXY-N-METHYLBENZAMIDE is used as a potential drug candidate in biological research studies, where it has shown promise for its potential biological activities and may lead to the discovery of new therapeutic agents.

Check Digit Verification of cas no

The CAS Registry Mumber 130250-62-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,0,2,5 and 0 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 130250-62:
(8*1)+(7*3)+(6*0)+(5*2)+(4*5)+(3*0)+(2*6)+(1*2)=73
73 % 10 = 3
So 130250-62-3 is a valid CAS Registry Number.

130250-62-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name N,2-Dimethoxy-N-methylbenzamide

1.2 Other means of identification

Product number -
Other names Benzamide,N,2-dimethoxy-N-methyl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:130250-62-3 SDS

130250-62-3Relevant articles and documents

Biocatalytic Strategy for the Highly Stereoselective Synthesis of CHF2-Containing Trisubstituted Cyclopropanes

Carminati, Daniela M.,Decaens, Jonathan,Couve-Bonnaire, Samuel,Jubault, Philippe,Fasan, Rudi

supporting information, p. 7072 - 7076 (2021/02/27)

The difluoromethyl (CHF2) group has attracted significant attention in drug discovery and development efforts, owing to its ability to serve as fluorinated bioisostere of methyl, hydroxyl, and thiol groups. Herein, we report an efficient biocat

Synthesis of various acylating agents directly from carboxylic acids

Pilathottathil, Fathima,Vineet Kumar, Doppalapudi,Kaliyamoorthy, Alagiri

supporting information, p. 1622 - 1632 (2020/04/27)

A straightforward synthesis of acylating reagents such as Weinreb and MAP amides from aromatic, aliphatic carboxylic acids, and amino acids using PPh3/NBS combination is described. A chemo-selective modification of the carboxylic acid group into Weinreb amide in the presence of more reactive aldehydes and ketones is presented. All reactions were performed at ambient temperature under air using undried commercial grade solvent. Furthermore, the present methodology could be performed at a gram scale under inert-free reaction conditions. In addition, 7-azaindoline amide auxiliary (used for catalytic asymmetric aldol- and Mannich-type reactions), which behaves like Weinreb amide is also synthesized under similar reaction conditions.

A small-molecule cell-based screen led to the identification of biphenylimidazoazines with highly potent and broad-spectrum anti-apicomplexan activity

Moine, Espérance,Denevault-Sabourin, Caroline,Debierre-Grockiego, Fran?oise,Silpa, Laurence,Gorgette, Olivier,Barale, Jean-Christophe,Jacquiet, Philippe,Brossier, Fabien,Gueiffier, Alain,Dimier-Poisson, Isabelle,Enguehard-Gueiffier, Cécile

, p. 386 - 400 (2014/12/11)

An in vitro screening of the anti-apicomplexan activity of 51 compounds, stemming from our chemical library and from chemical synthesis, was performed. As a study model, we used Toxoplasma gondii (T. gondii), expressing β-galactosidase for the colorimetric assessment of drug activity on parasites cultivated in vitro. This approach allowed the validation of a new series of molecules with a biphenylimidazoazine scaffold as inhibitors of T. gondii growth in vitro. Hence, 8 molecules significantly inhibited intracellular replication of T. gondii in vitro, with EC50 50 in the submicromolar to nanomolar range, for each parasite. These data, including the broad anti-parasite spectrum of these inhibitors, define a new generation of potential anti-parasite compounds of wide interest, including for veterinary application. Studies realized on E. tenella suggest that these molecules act during the intracellular development steps of the parasite. Further experiments should be done to identify the molecular target(s) of these compounds.

Copper-catalyzed synthesis of weinreb amides by oxidative amidation of alcohols

Yedage, Subhash L.,Bhanage, Bhalchandra M.

, p. 526 - 532 (2015/02/19)

A simple and efficient protocol has been developed for the oxidative amidation of alcohols to Weinreb amides using tert-butyl hydroperoxide as an oxidant and an inexpensive and air stable copper catalyst. The present protocol is advantageous as it uses commercially affordable alcohols as starting materials. The developed protocol also tolerates various substituted alcohols as starting materials to provide good to excellent yields of the desired products.

Synthesis and structure-activity relationships of benzophenone-bearing diketopiperazine-type anti-microtubule agents

Hayashi, Yoshio,Yamazaki, Yuri,Sumikura, Makiko,Masuda, Yurika,Hayashi, Yoshiki,Yasui, Hiroyuki,Kiso, Yoshiaki,Chinen, Takumi,Usui, Takeo,Yakushiji, Fumika,Potts, Barbara,Neuteboom, Saskia,Palladino, Michael,Lloyd, George Kenneth

experimental part, p. 4279 - 4289 (2012/09/08)

KPU-105 (4), a potent anti-microtubule agent that contains a benzophenone was derived from the diketopiperazine-type vascular disrupting agent (VDA) plinabulin 3, which displays colchicine-like tubulin depolymerization activity. To develop derivatives wit

A Weinreb amide approach to the synthesis of trifluoromethylketones

Rudzinski, Diandra M.,Kelly, Christopher B.,Leadbeater, Nicholas E.

supporting information, p. 9610 - 9612 (2012/10/29)

A novel route to access trifluoromethylketones (TFMKs) from Weinreb amides is reported. This represents the first documented case of the Ruppert-Prakash reagent (TMS-CF3) reacting in a constructive manner with an amide and enables synthesis of TMFKs without risk of over-trifluoromethylation.

Ru-catalyzed hydrogenation of 3,5-diketo amides: Simultaneous control of chemo- and enantioselectivity

Li, Wanfang,Fan, Weizheng,Ma, Xin,Tao, Xiaoming,Li, Xiaoming,Xie, Xiaomin,Zhang, Zhaoguo

supporting information, p. 8976 - 8978 (2012/11/07)

By modulating the chelating priorities of the different directing groups in 3,5-diketo amides with the assistance from coordinating solvent, highly chemo- and enantioselective hydrogenation of the C3-carbonyls was achieved in the presence of [RuCl(benzene)(S)-SunPhos]Cl in THF.

Palladium-catalyzed carbonylation reactions of aryl bromides at atmospheric pressure: A general system based on xantphos

Martinelli, Joseph R.,Watson, Donald A.,Freckmann, Dominique M. M.,Barder, Timothy E.,Buchwald, Stephen L.

supporting information; experimental part, p. 7102 - 7107 (2009/05/09)

(Chemical Equation Presented) A method for the Pd-catalyzed carbonylation of aryl bromides has been developed using Xantphos as the ligand. This method is effective for the direct synthesis of Weinreb amides, 1° and 2° benzamides, and methyl esters from the corresponding aryl bromides at atmospheric pressure. In addition, a putative catalytic intermediate, (Xanphos)Pd(Br)benzoyl, was prepared and an X-ray crystal structure was obtained revealing an unusual cis-coordination mode of Xantphos in this palladium-acyl complex.

PYRIDAZINONE COMPOUNDS AS CALCILYTICS

-

Page/Page column 48, (2010/11/27)

Various calcilytic compounds and pharmaceutical compositions containing these compounds are disclosed. Calcilytic compounds are compounds capable of inhibiting calcium receptor activity. Methods for preparing calcilytic compounds, oral bioavailability of calcilytic compounds, and their use as calcium receptor antagonists are also disclosed.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 130250-62-3