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(E)-ethyl 3-(2-ethoxypyriMidin-5-yl)acrylate is a chemical compound characterized by the molecular formula C11H15N3O3. It is a pyrimidine derivative featuring an ethyl ester group and an acrylate group attached to the pyrimidine ring, which contributes to its versatile applications in various fields.

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  • 1314533-99-7 Structure
  • Basic information

    1. Product Name: (E)-ethyl 3-(2-ethoxypyriMidin-5-yl)acrylate
    2. Synonyms: (E)-ethyl 3-(2-ethoxypyriMidin-5-yl)acrylate
    3. CAS NO:1314533-99-7
    4. Molecular Formula: C11H14N2O3
    5. Molecular Weight: 222.24046
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1314533-99-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (E)-ethyl 3-(2-ethoxypyriMidin-5-yl)acrylate(CAS DataBase Reference)
    10. NIST Chemistry Reference: (E)-ethyl 3-(2-ethoxypyriMidin-5-yl)acrylate(1314533-99-7)
    11. EPA Substance Registry System: (E)-ethyl 3-(2-ethoxypyriMidin-5-yl)acrylate(1314533-99-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1314533-99-7(Hazardous Substances Data)

1314533-99-7 Usage

Uses

Used in Organic Synthesis:
(E)-ethyl 3-(2-ethoxypyriMidin-5-yl)acrylate is used as a building block in organic synthesis for the creation of pharmaceuticals and other biologically active molecules. Its unique structure allows for the development of new compounds with potential therapeutic properties.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (E)-ethyl 3-(2-ethoxypyriMidin-5-yl)acrylate serves as a valuable reagent. It is utilized to introduce pyrimidine and acrylate functional groups into organic molecules, which can lead to the discovery of novel drugs with improved efficacy and selectivity.
Used in Chemical Reactions:
(E)-ethyl 3-(2-ethoxypyriMidin-5-yl)acrylate is also employed as a reagent in chemical reactions, where its functional groups can be strategically incorporated into target molecules to enhance their chemical and biological properties.
Used in Agrochemical Industry:
(E)-ethyl 3-(2-ethoxypyriMidin-5-yl)acrylate may have potential applications in the agrochemical industry. It can be used as a precursor for the synthesis of herbicides and fungicides, contributing to the development of more effective and environmentally friendly products for agricultural use.

Check Digit Verification of cas no

The CAS Registry Mumber 1314533-99-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,4,5,3 and 3 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1314533-99:
(9*1)+(8*3)+(7*1)+(6*4)+(5*5)+(4*3)+(3*3)+(2*9)+(1*9)=137
137 % 10 = 7
So 1314533-99-7 is a valid CAS Registry Number.

1314533-99-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl (E)-3-(2-ethoxypyrimidin-5-yl)prop-2-enoate

1.2 Other means of identification

Product number -
Other names (E)-ethyl-3-(2-ethoxypyrimidin-5-yl)acrylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1314533-99-7 SDS

1314533-99-7Relevant articles and documents

Feasible synthesis of the GPR40 antagonist by contructing 2-thiouracil ring VIA acid mediated cyclization

Zhao, Yongfeng,Liao, Jiayu

, p. 1145 - 1151 (2011)

GW1100 is an antagonist of GPR40 identified by high throughput screening recently. The feasible synthesis of GW1100 has been developed in mild conditions. The key step involves the cyclization of the 2-thiouracil heterocycle under acidic conditions at room temperature. The Japan Institute of Heterocyclic Chemistry.

The identification of a potent, water soluble inhibitor of lipoprotein-associated phospholipase A2

Boyd, Helen F.,Hammond, Beverley,Hickey, Deirdre M.B.,Ife, Robert J.,Leach, Colin A.,Lewis,Macphee, Colin H.,Milliner, Kevin J.,Pinto, Ivan L.,Smith, Stephen A.,Stansfield, Ian G.,Theobald, Colin J.,Whittaker, Caroline M.

, p. 701 - 704 (2007/10/03)

Modification of the pyrimidone 5-substituent in a series of 1-((amidolinked)-alkyl)-pyrimidones, lipophilic inhibitors of lipoprotein-associated phospholipase A2, has given inhibitors of nanomolar potency and improved physicochemical properties

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