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(2-bromoethoxy)cyclohexane is an organic compound that features a cyclohexane ring with a bromoethoxy group attached to it. This structure endows the molecule with unique properties, such as reactivity due to the bromine atom and solubility in organic solvents due to the ethoxy group. It serves as a versatile chemical building block in the chemical and pharmaceutical industries.

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  • 131665-94-6 Structure
  • Basic information

    1. Product Name: (2-bromoethoxy)cyclohexane
    2. Synonyms: (2-bromoethoxy)cyclohexane
    3. CAS NO:131665-94-6
    4. Molecular Formula: C8H15BrO
    5. Molecular Weight: 207.12
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 131665-94-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: (2-bromoethoxy)cyclohexane(CAS DataBase Reference)
    10. NIST Chemistry Reference: (2-bromoethoxy)cyclohexane(131665-94-6)
    11. EPA Substance Registry System: (2-bromoethoxy)cyclohexane(131665-94-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 131665-94-6(Hazardous Substances Data)

131665-94-6 Usage

Uses

Used in Chemical Synthesis:
(2-bromoethoxy)cyclohexane is used as a chemical intermediate for the synthesis of various organic compounds. The bromine atom in the molecule allows it to participate in nucleophilic substitution and addition reactions, making it a valuable component in creating a wide range of products.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (2-bromoethoxy)cyclohexane is used as a building block for the development of new drugs. Its unique structure and reactivity contribute to the creation of molecules with potential therapeutic applications.
Used in Research:
(2-bromoethoxy)cyclohexane is also utilized in research settings to study the properties and reactions of organic compounds. Its solubility and reactivity make it an interesting subject for scientific investigations, potentially leading to new discoveries and applications.

Check Digit Verification of cas no

The CAS Registry Mumber 131665-94-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,6,6 and 5 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 131665-94:
(8*1)+(7*3)+(6*1)+(5*6)+(4*6)+(3*5)+(2*9)+(1*4)=126
126 % 10 = 6
So 131665-94-6 is a valid CAS Registry Number.

131665-94-6Downstream Products

131665-94-6Relevant articles and documents

A General Approach to Deboronative Radical Chain Reactions with Pinacol Alkylboronic Esters

André-Joyaux, Emy,Kuzovlev, Andrey,Renaud, Philippe,Tappin, Nicholas D. C.

, p. 13859 - 13864 (2020/06/10)

The generation of carbon-centered radicals from air-sensitive organoboron compounds through nucleohomolytic substitution at boron is a general method to generate non-functionalized and functionalized radicals. Due to their reduced Lewis acidity, alkylboronic pinacol esters are not suitable substrates. We report their in situ conversion into alkylboronic catechol esters by boron-transesterification with a substoichiometric amount of catechol methyl borate combined with an array of radical chain processes. This simple one-pot radical-chain deboronative method enables the conversion of pinacol boronic esters into iodides, bromides, chlorides, and thioethers. The process is also suitable the formation of nitriles and allylated compounds through C?C bond formation using sulfonyl radical traps. The power of combining radical and classical boron chemistry is illustrated with a modular 5-membered ring formation using a combination of three-component coupling and protodeboronative cyclization.

DOPAMINE D2 RECEPTOR LIGANDS

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Page/Page column 128, (2016/07/05)

The present invention relates to novel dopamine D2 receptor ligands. The invention further relates to functionally-biased dopamine D2 receptor ligands and the use of these compounds for treating or preventing central nervous system and systemic disorders associated with dysregulation of dopaminergic activity. The present invention relates to novel compounds that modulate dopamine D2 receptors. In particular, compounds of the present invention show functional selectivity at the dopamine D2 receptors and exhibit selectivity downstream of the D2 receptors, on the 0- arrestin pathway and/or on the cAMP pathway.

SUBSTITUTED TRIAZOLO-PYRIMIDINE COMPOUNDS FOR MODULATING CELL PROLIFERATION, DIFFERENTIATION AND SURVIVAL

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Paragraph 0627; 0628, (2014/05/25)

Disclosed herein are erythropoietin-mimetic compounds of Formula I, which modulate the survival, function, or differentiation of, for example, kidney cells, neurons, erythroid cells, or other erythropoietin-responsive cells. The present invention also relates to compounds and methods that preferentially modulate cells expressing the tissue-protective erythropoietin receptor. The compounds of the invention are useful in preventing and treating diseases, such as anemia, organ injury, and diseases of the central nervous system, and as an adjunct to cellular treatments, such as stem cell therapies.

Enhancement of reaction efficiency by functionalized alcohols on gold(I)-catalyzed intermodular hydroalkoxylation of unactivated olefins

Hirai, Toshifumi,Hamasaki, Aklyuki,Nakamura, Aki,Tokunaga, Makoto

supporting information; experimental part, p. 5510 - 5513 (2010/02/28)

"Chemical Equation Presented" Intermolecular hydroalkoxylation of unactivated olefins catalyzed by the combination of gold(I) and electron deficient phosphine ligands has been developed. Although pairings of unactivated olefins and common aliphatic alcohols gave unsatisfactory results In gold catalyzed hydroalkoxylations, the use of alcohol substrates bearing coordination functionalities such as halogen or alkoxy groups showed great improvement of reactivity.

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