133545-17-2

Basic information

• Product Name: S(-)-2 2-BIS-(DIPHENYLPHOSPHINO)-6 6-DIM
• Synonyms: S(-)-2 2-BIS-(DIPHENYLPHOSPHINO)-6 6-DIM;(S)-(-)-(6,6'-Dimethoxybiphenyl-2,2'-diyl)bis(diphenylphosphine);(S)-(-)-2,2'-Bis(diphenylphosphino)-6,6'-dimethoxy-1,1'-biphenyl,min.97%(S)-MeO-BIPHEP;(S)-(-)-MeO-BIPHEP, SL-A101-2, (S)-(-)-2,2μ-Bis(diphenylphosphino)-6,6μ-dimethoxy-1,1μ-biphenyl;97% (S)-MeO-BIPHEP;(S)-(-)-2,2'-Bis(diphenylphosphino)-6,6'-diMethoxy-1,1'-biphenyl,(S)-MeO-BIPHEP;(S)-(-)-2,2'-Bis(diphenylphosphino)-6,6'-dimethoxy-1,1'-biphenyl,97% (S)-MeO-BIPHEP;(S)-(-)-2,3'-Bis(diphenylphosphino)-6-6'-dimethoxy-1,1'-biphenyl
• CAS NO: 133545-17-2
• Molecular Formula: C₃₈H₃₂O₂P₂
• Molecular Weight: 582.607002
• Product Categories: Chiral Phosphine;MeOBIPHEP Series
• Mol File: 133545-17-2.mol

Chemical Properties

• Melting Point: 213-216 °C
• Boiling Point: 651.1±55.0 °C(Predicted)
• Appearance: white/crystal
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• BRN: 4790083
• CAS DataBase Reference: S(-)-2 2-BIS-(DIPHENYLPHOSPHINO)-6 6-DIM(CAS DataBase Reference)
• NIST Chemistry Reference: S(-)-2 2-BIS-(DIPHENYLPHOSPHINO)-6 6-DIM(133545-17-2)
• EPA Substance Registry System: S(-)-2 2-BIS-(DIPHENYLPHOSPHINO)-6 6-DIM(133545-17-2)

Safety Data

• WGK Germany: 3
• F: 8-10-23
• Hazardous Substances Data: 133545-17-2(Hazardous Substances Data)

Usage

Uses

Used in Chemical Industry:
S(-)-2,2-BIS-(DIPHENYLPHOSPHINO)-6,6-DIM is used as a catalyst for various chemical reactions due to its enhanced catalytic efficiency.
Used in Pharmaceutical Industry:
S(-)-2,2-BIS-(DIPHENYLPHOSPHINO)-6,6-DIM is used as a catalyst in the synthesis of pharmaceutical compounds, contributing to the development of greener and more efficient drug production processes.
Used in Environmental Applications:
S(-)-2,2-BIS-(DIPHENYLPHOSPHINO)-6,6-DIM is used as a catalyst in environmental processes, such as pollution control and waste management, to promote greener and more sustainable solutions.

InChI:InChI=1/C38H32O2P2/c1-39-33-25-15-27-35(41(29-17-7-3-8-18-29)30-19-9-4-10-20-30)37(33)38-34(40-2)26-16-28-36(38)42(31-21-11-5-12-22-31)32-23-13-6-14-24-32/h3-28H,1-2H3

Upstream product

• 133545-15-0 (RS)-(6,6'-dimethoxybiphenyl-2,2'-diyl)bis(diphenylphosphine oxide) 
• 2398-37-0 3-methoxyphenyl bromide 
• 13145-84-1 (3-methoxyphenyl)(diphenyl)phosphane 
• 95278-09-4 (3-methoxylphenyl)diphenylphosphine oxide 
• 134435-27-1 (2-bromo-3-methoxyphenyl)diphenylphosphine oxide 
• 133545-14-9 (2-iodo-3-methoxyphenyl)diphenylphosphine oxide 
• 1079-66-9 chloro-diphenylphosphine 
• 3335-35-1 4-methyl-1-(trichloromethyl)benzene 
• 7732-18-5 water 
• 133545-15-0 (Ra)-(6,6'-dimethoxybiphenyl-2,2'-diyl)bis(diphenylphosphine oxide) 
• 133545-15-0 (Sa)-(6,6'-dimethoxybiphenyl-2,2'-diyl)bis(diphenylphosphine oxide) 

Downstream Products

• 1147564-30-4 [RuH(1,2-bis(dimethylphosphino)ethane)((R)-MeO-BiPHEP)][tetraphenylborate] 
• 373388-98-8 PdBr(C₆F₅)((S)-MeO-biphep) 
• 221154-87-6 Pd(dibenzylidene acetone)((S)-MeO-biphep) 
• 221154-98-9 PdI(C₆F₅)((S)-MeO-biphep) 
• 221154-96-7 PdI(MeOOC-C₆H₄)((S)-MeO-biphep) 
• 221155-04-0 Pd(cyclopent-4-ene-1,3-dione)((S)-MeO-biphep) 
• 221154-93-4 PdBr(p-NCC₆H₄)((S)-((C₆H₃(OCH₃)P(C₆H₅)2)2)) 
• 299197-81-2 ((Z,Z)-cycloocta-1,5-diene){(R)-(6,6'-dimethoxybiphenyl-2,2'-diyl)bis(diphenylphosphine)}rhodium(I) tetrafluoroborate 
• 133548-33-1 ((Z,Z)-cycloocta-1,5-diene){(R)-(6,6'-dimethoxybiphenyl-2,2'-diyl)bis(diphenylphosphine)}rhodium(I) perchlorate 
• 1134789-66-4 [((S)-2,2'-bis(diphenylphosphino)-6,6'-dimethoxy-1,1'-biphenyl)(AuCl)2] 
• 181955-02-2 Pt(CH₃)(Cl)((CH₃OC₆H₃P(C₆H₅)2)2) 
• 199541-16-7 [RuCl(S-(6,6'-dimethoxybiphenyl-2,2'-diyl)bis(diphenylphosphine))(benzene)]Cl 
• 161584-40-3 Ru4(μ-H)4((S)-(-)-2,2'-bis(diphenylphosphino)-6,6'-dimethoxy-1,1'-biphenyl) * n-heptane 

Relevant articles and documents

Process for producing optically active gamma-butyrolactone

This invention provides a novel process for producing optically active 3-hydroxy-γ-butyrolactone in a short step, which is superior economically and in efficiency and industrially suitable by using a starting material which is inexpensive and easily available and reagents easy to handle. This invention relates to a process for producing optically active 3-hydroxy-γ-butyrolactone represented by formula I: wherein the symbol * means an asymmetric carbon atom, which comprises hydrogenating an optically active 4-substituted oxy-3-hydroxybutyrate represented by formula II: wherein R1 represents a C1-4 lower alkyl group, R2 represents a protective group for a hydroxyl group deprotected by hydrogenation with a heterogeneous hydrogenation catalyst, and the symbol * has the same meaning as defined above, in the presence of a heterogeneous hydrogenation catalyst and an acidic substance followed by deprotection and simultaneous ring closure thereof.

Method for producing 1-menthol

Provided is a method for the production of 1-menthol, which comprises hydrogenation of piperitenone with a transition metal complex of a specified optically active phosphine to produce pulegone, hydrogenation of the obtained pulegone with a ruthenium-phosphine-amine complex in the presence of base to obtain pulegol, and further hydrogenation of the pulegol with a transition metal catalyst.

Process for preparing oprtically active trimethyllactic acid and its ester

The invention relates to a novel process for preparing optically active trimethyllactic acid and/or its esters by catalytic hydrogenation of trimethylpyruvic acid and/or its esters in the presence of noble metal complex catalysts containing phosphorus ligands.

Chiral phosphorus compounds

Novel chiral phosphorus compounds of the formula STR1 wherein R signifies lower alkyl, R1 signifies phenyl and R2 and R3 signify hydrogen or lower alkoxy, which are suitable in the form of complexes with a metal of Group VIII as catalysts for asymmetric hydrogenations and for enantioselective hydrogen displacements in prochiral allylic systems.

Chiral phosphines

Novel, racemic and optically active phosphorus compounds of the formula STR1 wherein R signifies lower alkyl, lower alkoxy or protected hydroxy, R1 signifies lower alkoxy, phenoxy, benzyloxy, chlorine or bromine, R2 stands for lower alkyl or lower alkoxy and n represents the number 0, 1 or 2, are described. These compounds are valuable intermediates in the manufacture of not only known, but also novel diphosphine ligands.

Asymmetrical hydrogenation

There is disclosed a process for the asymmetrical hydrogenation of (E)-2-methyl-3-phenyl-2-propen-1-ol of formula STR1 wherein R1 is as defined herein, to give compounds of formula STR2 The catalyst is a neutral or cationic rhodium complex of a chiral atropisomeric phosphine.

Axially Dissymmetric Diphosphines in the Biphenyl Series: Synthesis of (6,6'-Dimethoxybiphenyl-2,2'-diyl)bis(diphenylphosphine) ('MeO-BIPHEP') and Analogues via an ortho-Lithiation/Iodination Ullmann-Reaction Approach

The new axially dissymmetric diphosphines (R)- and (S)-(6,6'-dimethoxybiphenyl-2,2'-diyl)bis(diphenylphosphine) ((R)- and (S)-5a; 'MeO-BIPHEP') and the analogues (R)- and (S)-5b and 5c have been synthesized in enantiomerically pure form.These lignands hav