136834-20-3

Basic information

• Product Name: N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine
• Synonyms: N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine;Bz-2'-F-dA;Adenosine, N-benzoyl-2'-deoxy-2'-fluoro-;N-Benzoyl-2'-deoxy-2'-fluoroadenosine;N6-Benzoyl-2'-deoxy-2'-fluoroadenosine
• CAS NO: 136834-20-3
• Molecular Formula: C₁₇H₁₆FN₅O₄
• Molecular Weight: 373.3384432
• Mol File: 136834-20-3.mol

Chemical Properties

• Appearance: /
• Density: 1.67±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 7.87±0.43(Predicted)
• CAS DataBase Reference: N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine(CAS DataBase Reference)
• NIST Chemistry Reference: N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine(136834-20-3)
• EPA Substance Registry System: N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine(136834-20-3)

Safety Data

• Hazardous Substances Data: 136834-20-3(Hazardous Substances Data)

Usage

Uses

Used in Medicinal Chemistry Research:
N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine is utilized as a research tool in medicinal chemistry to explore the effects of specific structural modifications on nucleoside analogs. Its unique structure allows scientists to investigate how these changes influence the compound's interactions with biological systems and its potential therapeutic applications.
Used in Drug Discovery:
In the field of drug discovery, N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine serves as a valuable compound for identifying and developing new therapeutic agents. Its modified structure may confer novel biological activities, making it a candidate for the treatment of various diseases and conditions. N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine's potential applications could span across different therapeutic areas, depending on the outcomes of ongoing research and development efforts.

Upstream product

• 98-88-4 benzoyl chloride 
• 20187-82-0 2'-fluorodeoxyadenosine 
• 58-61-7 adenosine 
• 5536-17-4 arabinosyl adenine 
• 136834-19-0 N⁶-benzoyl-9-<2-O-(trifluoromethylsulfonyl)-3,5-di-O-tetrahydropyran-2-yl-β-D-arabinofuranosyl>adenine 
• 136834-18-9 N⁶-benzoyl-9-(3,5-di-O-tetrahydropyran-2-yl-β-D-arabinofuranosyl)adenine 
• 79896-97-2 N6-benzoyl-9-β-D-arabinofuranosyladenine 
• 146954-64-5 N⁶-benzoyl-2'-deoxy-2'-fluoro-3',5'-di-O-tetrahydropyran-2-yladenosine 

Downstream Products

• 136834-21-4 N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)3-fluoro-4-hydroxytetrahydrofuran-2-yl)9H-purin-6yl)benzamide triethylammonium salt 
• 136834-22-5 N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenyl-methoxy]methyl]-4-[2-cyanoethoxy-(diisopropylamino)phosphanyl]oxy-3-fluoro-tetrahydrofuran-2-yl]purin-6-yl]benzamide 
• 1244763-23-2 C₄₄H₄₈FN₅O₆Si 

Relevant articles and documents

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The invention discloses cyclic dinucleotide analogues, a pharmaceutical composition of the analogues and applications of the analogues and the pharmaceutical composition. The cyclic dinucleotide analogs (I), an isomer, prodrug, stable isotope derivative or pharmaceutically acceptable salt of the analogs have a structure shown in the specification. The cyclic dinucleotide analogs provided by the invention can be used as regulators of stimulator of interferon genes (STIG) and related signaling pathways, and can effectively treat and/or alleviate multiple types of diseases, including but not limited to malignant tumors, inflammation, autoimmune diseases and infectious diseases; and in addition, the STING regulators can also be used as vaccine adjuvants.

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