Welcome to LookChem.com Sign In|Join Free

CAS

  • or
N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine is a nucleoside analog chemical compound derived from adenosine, a fundamental building block of DNA and RNA. It features a benzoyl group at the N6 position and a fluoro group at the 2' position of the sugar moiety, which are structural modifications that can significantly alter its properties and biological activity. N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine is a promising candidate for research in medicinal chemistry and drug discovery.

136834-20-3 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • China Biggest Factory Manufacturer Supply N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine CAS 136834-20-3

    Cas No: 136834-20-3

  • USD $ 1.0-2.0 / Kilogram

  • 500 Kilogram

  • 20 Metric Ton/Month

  • Leader Biochemical Group
  • Contact Supplier
  • 136834-20-3 Structure
  • Basic information

    1. Product Name: N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine
    2. Synonyms: N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine;Bz-2'-F-dA;Adenosine, N-benzoyl-2'-deoxy-2'-fluoro-;N-Benzoyl-2'-deoxy-2'-fluoroadenosine;N6-Benzoyl-2'-deoxy-2'-fluoroadenosine
    3. CAS NO:136834-20-3
    4. Molecular Formula: C17H16FN5O4
    5. Molecular Weight: 373.3384432
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 136834-20-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.67±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. PKA: 7.87±0.43(Predicted)
    10. CAS DataBase Reference: N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine(CAS DataBase Reference)
    11. NIST Chemistry Reference: N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine(136834-20-3)
    12. EPA Substance Registry System: N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine(136834-20-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 136834-20-3(Hazardous Substances Data)

136834-20-3 Usage

Uses

Used in Medicinal Chemistry Research:
N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine is utilized as a research tool in medicinal chemistry to explore the effects of specific structural modifications on nucleoside analogs. Its unique structure allows scientists to investigate how these changes influence the compound's interactions with biological systems and its potential therapeutic applications.
Used in Drug Discovery:
In the field of drug discovery, N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine serves as a valuable compound for identifying and developing new therapeutic agents. Its modified structure may confer novel biological activities, making it a candidate for the treatment of various diseases and conditions. N6-Benzoyl-2'-Fluoro-2'-deoxyadenosine's potential applications could span across different therapeutic areas, depending on the outcomes of ongoing research and development efforts.

Check Digit Verification of cas no

The CAS Registry Mumber 136834-20-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,6,8,3 and 4 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 136834-20:
(8*1)+(7*3)+(6*6)+(5*8)+(4*3)+(3*4)+(2*2)+(1*0)=133
133 % 10 = 3
So 136834-20-3 is a valid CAS Registry Number.

136834-20-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name N6-benzoyl-2 deoxy-2 -fluoroadenosine

1.2 Other means of identification

Product number -
Other names BZ-2'-F-DA

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:136834-20-3 SDS

136834-20-3Relevant articles and documents

CYCLIC DINUCLEOTIDE COMPOUND AND USES THEREOF

-

Paragraph 0076-0079, (2021/11/05)

Provided are a compound of formula (I), an optical isomer thereof, a pharmaceutically acceptable salt thereof, uses of said compound acting as a STING agonist.

Cyclic dinucleotide analogues, pharmaceutical composition of analogues and applications of analogues and pharmaceutical composition

-

Paragraph 0432; 0433; 0434, (2020/04/17)

The invention discloses cyclic dinucleotide analogues, a pharmaceutical composition of the analogues and applications of the analogues and the pharmaceutical composition. The cyclic dinucleotide analogs (I), an isomer, prodrug, stable isotope derivative or pharmaceutically acceptable salt of the analogs have a structure shown in the specification. The cyclic dinucleotide analogs provided by the invention can be used as regulators of stimulator of interferon genes (STIG) and related signaling pathways, and can effectively treat and/or alleviate multiple types of diseases, including but not limited to malignant tumors, inflammation, autoimmune diseases and infectious diseases; and in addition, the STING regulators can also be used as vaccine adjuvants.

CYCLIC DINUCLEOTIDES AS STING AGONISTS

-

Page/Page column 109; 138; 156; 157; 158; 174; 175, (2018/08/20)

Disclosed are compounds, compositions and methods for treating of diseases, syndromes, or disorders that are affected by the modulation of STING. Such compounds are represented by Formula (I) as follows: wherein R, R1B, R1C, R2B

Synthesis and anti-HCV activity of 3′,4′-oxetane nucleosides

Chang, Wonsuk,Du, Jinfa,Rachakonda, Suguna,Ross, Bruce S.,Convers-Reignier, Serge,Yau, Wei T.,Pons, Jean-Francois,Murakami, Eisuke,Bao, Haiying,Steuer, Holly Micolochick,Furman, Phillip A.,Otto, Michael J.,Sofia, Michael J.

scheme or table, p. 4539 - 4543 (2010/11/03)

Hepatitis C virus afflicts approximately 180 million people worldwide and currently there are no direct acting antiviral agents available to treat this disease. Our first generation nucleoside HCV inhibitor, RG7128 has already established proof-of-concept

INHIBITORS OF S-ADENOSYL-L-METHIONINE DECARBOXYLASE

-

, (2009/01/23)

Novel mechanism-based inhibitors of S-adenosyl-L-methionine decarboxylase are provided. These compounds of formula (1) inhibit the life cycle of trypanosomes, and are useful to treat subjects infected with African trypanosomes. The invention includes pharmaceutical compositions and methods of using the compounds of formula (1).

Antisense modulation of CD40 ligand expression

-

Page/Page column 17, (2008/06/13)

Antisense compounds, compositions and methods are provided for modulating the expression of CD40 ligand. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding CD40 ligand. Methods of using these compounds for modulation of CD40 ligand expression and for treatment of diseases associated with expression of CD40 ligand are provided.

Modulation of CEACAM1 expression

-

Page/Page column 25; 26, (2010/02/11)

Compounds, compositions and methods are provided for modulating the expression of CEACAM1. The compositions comprise oligonucleotides, targeted to nucleic acid encoding CEACAM1. Methods of using these compounds for modulation of CEACAM1 expression and for diagnosis and treatment of disease associated with expression of CEACAM1 are provided.

Antisense modulation of polo-like kinase expression

-

Page/Page column 18, (2008/06/13)

Antisense compounds, compositions and methods are provided for modulating the expression of polo-like kinase. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding polo-like kinase. Methods of using these compounds for modulation of polo-like kinase expression and for treatment of diseases associated with expression of polo-like kinase are provided.

Antisense modulation of perilipin expression

-

Page/Page column 15, (2008/06/13)

Antisense compounds, compositions and methods are provided for modulating the expression of perilipin. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding perilipin. Methods of using these compounds for modulation of perilipin expression and for treatment of diseases associated with expression of perilipin are provided.

Antisense modulation of CDC14A expression

-

Page/Page column 15, (2010/02/06)

Antisense compounds, compositions and methods are provided for modulating the expression of CDC14A. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding CDC14A. Methods of using these compounds for modulation of CDC14A expression and for treatment of diseases associated with expression of CDC14A are provided.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 136834-20-3