141699-58-3

Basic information

• Product Name: 1-(Tert-butoxycarbonyl)-3-(methanesulfonyloxy)azetidine
• Synonyms: 1-(Tert-butoxycarbonyl)-3-(methanesulfonyloxy)azetidine;1-(tert-butoxycarbonyl)azetidine-3-yl-methanesulfonate;N-Boc-3-methanesulfonyloxyazetidine;1-Boc-3-methanesulfonyloxy-azetidine;3-((Methylsulfonyl)oxy)azetidine-1-carboxylic acid tert-butyl ester;3-[(Methanesulfonyl)oxy]azetidine-1-carboxylic acid tert-butyl ester;tert-Butyl 3-[(methylsulfonyl)oxy]azetane-1-carboxylate;tert-Butyl 3-[(methylsulfonyl)oxy]-1-azetidinecarboxylate
• CAS NO: 141699-58-3
• Molecular Formula: C₉H₁₇NO₅S
• Molecular Weight: 251.29998
• Product Categories: CMLLYL
• Mol File: 141699-58-3.mol

Chemical Properties

• Melting Point: 69 °C
• Boiling Point: 378.534°C at 760 mmHg
• Flash Point: 182.731°C
• Appearance: /
• Density: 1.283g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.504
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: -4.18±0.40(Predicted)
• CAS DataBase Reference: 1-(Tert-butoxycarbonyl)-3-(methanesulfonyloxy)azetidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(Tert-butoxycarbonyl)-3-(methanesulfonyloxy)azetidine(141699-58-3)
• EPA Substance Registry System: 1-(Tert-butoxycarbonyl)-3-(methanesulfonyloxy)azetidine(141699-58-3)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• RIDADR: UN 2811 6.1 / PGIII
• HazardClass: IRRITANT
• Hazardous Substances Data: 141699-58-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Development:
1-(Tert-butoxycarbonyl)-3-(methanesulfonyloxy)azetidine is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and reactivity allow for the creation of complex amine derivatives, which are essential building blocks in the development of new drugs.
Used in Agrochemical Synthesis:
In the agrochemical industry, 1-(Tert-butoxycarbonyl)-3-(methanesulfonyloxy)azetidine is utilized as a reagent for the synthesis of amine-containing agrochemicals. Its ability to facilitate complex synthetic transformations contributes to the development of novel and effective agrochemicals for crop protection and pest control.
Used in Fine Chemicals Production:
1-(Tert-butoxycarbonyl)-3-(methanesulfonyloxy)azetidine is employed as a versatile building block in the production of fine chemicals. Its stability and reactivity enable the synthesis of a wide range of specialty chemicals, including chiral compounds, which are important in various industrial applications, such as fragrances, flavors, and pharmaceutical intermediates.
Used in Organic Synthesis Research:
As a reagent in organic synthesis, 1-(Tert-butoxycarbonyl)-3-(methanesulfonyloxy)azetidine is used for exploring new synthetic methodologies and reaction mechanisms. Its unique properties provide opportunities for researchers to investigate novel approaches to the synthesis of amine derivatives and other complex organic molecules.

InChI:InChI=1/C9H17NO5S/c1-9(2,3)14-8(11)10-5-7(6-10)15-16(4,12)13/h7H,5-6H2,1-4H3

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 141699-55-0 tert-butyl 3-hydroxyazetidine-1-carboxylate 
• 398489-26-4 tert-butyl 3-oxoazetidine-1-carboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 36476-89-8 azetidin-3-yl methanesulfonate hydrochloride 
• 67160-19-4 3-methanesulfonyloxy-azetidine 

Downstream Products

• 178312-51-1 1-(t-Butoxycarbonyl)-3-(3-hydroxypiperidyl)azetidine 
• 877399-35-4 tert-butyl 3-(4-(4,4,5,5,-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)-azetidine-1-carboxylate 
• 1227467-04-0 3-(3-bromo-phenoxy)-azetidine-1-carboxylic acid tert-butyl ester 
• 1443670-33-4 tert-butyl (S)-3-(4-(1-acetamidoethyl)phenoxy)azetidine-1-carboxylate 
• 1151651-24-9 3-[4-amino-3-(4-chloro-phenyl)-pyrazolo[3,4-d]pyrimidin-1-yl]-azetidine-1-carboxylic acid tert-butyl ester 
• 511277-83-1 6-[4-(3-azetidinoxy-1-carboxylic acid tert-butyl ester)-5-ethyl-2-methoxy-phenyl]-pyridin-2-ylamine 
• 1018966-46-5 C₂₆H₂₈N₈O₄S₃ 
• 178312-50-0 4-(3-azetidinyl)morpholine dihydrochloride 
• 254454-54-1 tert-butyl-3-iodoazetidine-1-carboxylate 
• 178311-48-3 1-(Tert-butoxycarbonyl)-3-(1-piperazinyl)azetidine 
• 877399-34-3 tert-butyl 3-(4-bromo-1H-pyrazol-1-yl)azetidine-1-carboxylate 
• 429672-02-6 tert-butyl 3-azidoazetidine-1-carboxylate 
• 206446-44-8 tert-butyl 3-benzoylazetidine-1-carboxylate 
• 206446-39-1 1-tert-butyl 3-(pyridine-2-yl)azetidine-1-carboxylate 

Relevant articles and documents

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