145100-54-5

Basic information

• Product Name: BENZYL 2-N-PROPYL-4-OXO-3,4-DIHYDROPYRIDINE-1(2H)-CARBOXYLATE
• Synonyms: BENZYL 2-N-PROPYL-4-OXO-3,4-DIHYDROPYRIDINE-1(2H)-CARBOXYLATE;benzyl 4-oxo-2-propyl-3,4-dihydropyridine-1(2H)-carboxylate;Benzyl 2-propyl-4-oxo-3,4-dihydropyridine-1(2H)-carboxylate
• CAS NO: 145100-54-5
• Molecular Formula: C₁₆H₁₉NO₃
• Molecular Weight: 273.33
• Mol File: 145100-54-5.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: BENZYL 2-N-PROPYL-4-OXO-3,4-DIHYDROPYRIDINE-1(2H)-CARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: BENZYL 2-N-PROPYL-4-OXO-3,4-DIHYDROPYRIDINE-1(2H)-CARBOXYLATE(145100-54-5)
• EPA Substance Registry System: BENZYL 2-N-PROPYL-4-OXO-3,4-DIHYDROPYRIDINE-1(2H)-CARBOXYLATE(145100-54-5)

Safety Data

• Hazardous Substances Data: 145100-54-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
BENZYL 2-N-PROPYL-4-OXO-3,4-DIHYDROPYRIDINE-1(2H)-CARBOXYLATE is used as a potential active pharmaceutical ingredient for its possible biological activity, which may be harnessed in the development of new drugs. Its unique structure could offer novel mechanisms of action or selectivity in treating various medical conditions.
Used in Organic Synthesis:
In the field of organic synthesis, BENZYL 2-N-PROPYL-4-OXO-3,4-DIHYDROPYRIDINE-1(2H)-CARBOXYLATE serves as a key intermediate or building block in the synthesis of more complex organic molecules. Its versatile functional groups can be manipulated to form a variety of derivatives with different properties and applications.
Note: Since the provided materials do not specify particular applications or industries for BENZYL 2-N-PROPYL-4-OXO-3,4-DIHYDROPYRIDINE-1(2H)-CARBOXYLATE, the uses listed above are general and based on the compound's potential properties and typical applications of similar compounds in the pharmaceutical and organic synthesis industries. Further research would be necessary to confirm these uses and identify specific applications.

Upstream product

• 626-64-2 pyridin-4-ol 
• 927-77-5 n-propylmagnesium bromide 
• 620-08-6 4-methoxypyridine 
• 2234-82-4 1-propylmagnesium chloride 
• 501-53-1 benzyl chloroformate 

Downstream Products

• 146253-91-0 N-<(Benzyloxy)carbonyl>-4-chloro-2-propyl-1,2-dihydropyridine 
• 1245646-49-4 benzyl 2-propyl-4-oxopiperidine-1-carboxylate 
• 146253-97-6 N-<(Benzyloxy)carbonyl>-4-chloro-3-methyl-2-propyl-1,2-dihydropyridine 
• 145100-59-0 2-Propyl-4-trifluoromethanesulfonyloxy-3,6-dihydro-2H-pyridine-1-carboxylic acid benzyl ester 
• 146253-96-5 N-<(Benzyloxy)carbonyl>-trans-3-methyl-2-propyl-2,3-dihydro-4-pyridone 

Relevant articles and documents

Highly Enantioselective Catalytic Addition of Grignard Reagents to N-Heterocyclic Acceptors

General methods to prepare chiral N-heterocyclic molecular scaffolds are greatly sought after because of their significance in medicinal chemistry. Described here is the first general catalytic methodology to access a wide variety of chiral 2- and 4-substituted tetrahydro-quinolones, dihydro-4-pyridones, and piperidones with excellent yields and enantioselectivities, utilizing a single catalyst system.

Catalytic enantioselective addition of dialkylzinc reagents to N-acylpyridinium salts

(Chemical equation presented) A pinch of salt: The first catalytic addition of dialkylzinc reagents to N-acylpyridinium salts with good yields and excellent enantioselectivities uses a copper-(S)-L complex as the catalyst. The versatility of the method is

C-3 acetoxylation of N-acyl-2,3-dihydro-4-pyridones

Stereoselective acetoxylation at the C-3 position of N-acyl-2-alkyl- 2,3-dihydro-4-pyridones was effected with Pb(OAc)4 in refluxing toluene.

Conversion of N-Acyl-2,3-dihydro-4-pyridones to 4-Chloro-1,2-dihydropyridines Using the Vilsmeier Reagent. Synthesis of (-)-Coniine and (+/-)-Lupinine

The full details are given of a study on the conversion of dihydropyridones of the type 3 to 4-chloro-1,2-dihydropyridines 4 using a Vilsmeier reagent.The use of 1 equiv of Vilsmeier reagent under mild conditions (ClCHCCl2, rt) transformed several racemic