145602-87-5

Basic information

• Product Name: 3-AMINO-1-BENZYLPYRROLIDINE-3-CARBOXYLIC ACID
• Synonyms: 3-AMINO-1-BENZYL-3-PYRROLIDINECARBOXYLIC ACID;3-AMINO-1-BENZYLPYRROLIDINE-3-CARBOXYLIC ACID;3-AMINO-1-BENZYLPYRROLIDINE-3-CARBOXYLIC ACID-2HBr
• CAS NO: 145602-87-5
• Molecular Formula: C₁₂H₁₆N₂O₂
• Molecular Weight: 220.27
• Product Categories: pharmacetical;Carboxylic Acids;Pyrrolidines;Carboxylic Acids
• Mol File: 145602-87-5.mol

Chemical Properties

• Boiling Point: 371.22 °C at 760 mmHg
• Flash Point: 178.308 °C
• Appearance: /
• Density: 1.982
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.605
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 1.91±0.20(Predicted)
• CAS DataBase Reference: 3-AMINO-1-BENZYLPYRROLIDINE-3-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-1-BENZYLPYRROLIDINE-3-CARBOXYLIC ACID(145602-87-5)
• EPA Substance Registry System: 3-AMINO-1-BENZYLPYRROLIDINE-3-CARBOXYLIC ACID(145602-87-5)

Safety Data

• Hazardous Substances Data: 145602-87-5(Hazardous Substances Data)

Usage

Uses

3-amino-1-benzylpyrrolidine-3-carboxylic acid is a useful research chemical.

InChI:InChI=1/C12H16N2O2/c13-12(11(15)16)6-7-14(9-12)8-10-4-2-1-3-5-10/h1-5H,6-9,13H2,(H,15,16)

Upstream product

• 28863-87-8 7-benzyl-1,3,7-triazaspiro[4.4]nonane-2,4-dione 
• 123-75-1 pyrrolidine 
• 145090-28-4 3-Amino-1-benzyl-pyrrolidine-3-carbonitrile 
• 7732-18-5 water 
• 1319059-78-3 C₂₁H₂₀N₂O₄ 
• 775-16-6 N-benzyl-3-pyrrolidinone 

Downstream Products

• 475469-12-6 3-amino-1-benzyl-3-ethoxycarbonylpyrrolidine 
• 475469-13-7 3-amino-1-benzyl-3-hydroxymethylpyrrolidine 
• 475469-15-9 (3-hydroxymethyl-pyrrolidin-3-yl)-carbamic acid tert-butyl ester 
• 475469-14-8 1-benzyl-3-N-tert-butoxycarbonylamino-3-hydroxymethylpyrrolidine 
• 39739-38-3 cucurbitine hydrochloride 

Relevant articles and documents

G protein coupled receptor agonist and application thereof in treatment of diabetes

The invention discloses a structure of a compound. The structural formula of the compound is shown in the description. Found by activity determination, the structure has the effect of a G protein coupled receptor 119 agonist; the G protein coupled receptor 119 agonist has the functions of not causing hypoglycemia of patients and promoting GLP-1 secretion. The compound disclosed by the invention can be further researched and developed as a diabetes-resisting drug. Besides, the invention further discloses a synthesis route and a synthesis method for the compound.

METHOD FOR CUCURBITINE SYNTHESIS

A method for the synthesis of cucurbitine comprising the step of forming a pyrrolidine ring by a 1,3 dipolar cycloaddition reaction.

Synthesis and structure-activity relationships of novel 7-substituted 1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acids as antitumor agents. Part 1

In an attempt to search for clinically useful antitumor agents, we have discovered that a series of 1,7-disubstituted-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids possessed moderate cytotoxic activity. We investigated the structure-acti

Antiallergic cosmetic or pharmaceutical composition

The invention relates to the use of cucurbitine or extracts of Cucurbitaceae pips for the preparation of a cosmetic or pharmaceutical, in particular dermatological, composition having antiallergic activity, or for the preparation of cosmetic or pharmaceutical compositions having a reduced risk of being allergenic.