145739-56-6 Usage
Uses
Used in Pharmaceutical Research and Drug Development:
6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid is used as a potential candidate for the development of new drugs due to its unique molecular structure and the possibility of exhibiting biological activity against various diseases and conditions.
Used in Organic Chemistry:
In the field of organic chemistry, 6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid is utilized as a building block or intermediate for the synthesis of more complex molecules, potentially leading to the creation of novel compounds with specific applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 145739-56-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,7,3 and 9 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 145739-56:
(8*1)+(7*4)+(6*5)+(5*7)+(4*3)+(3*9)+(2*5)+(1*6)=156
156 % 10 = 6
So 145739-56-6 is a valid CAS Registry Number.
InChI:InChI=1/C19H18N2O4S/c1-3-24-16-9-8-12(10-17(16)25-4-2)18-21-15(11-26-18)13-6-5-7-14(20-13)19(22)23/h5-11H,3-4H2,1-2H3,(H,22,23)
145739-56-6Relevant articles and documents
TETOMILAST POLYMORPHS
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Page/Page column 53-55, (2008/06/13)
The present invention provides a tetomilast crystal that is industrially easily produced in a large volume. (1) a tetomilast hydrate crystal having a powder X-ray diffraction spectrum that is substantially the same as the powder X-ray diffraction spectrum
Novel thiazole derivatives as inhibitors of superoxide production by human neutrophils: Synthesis and structure-activity relationships
Chihiro,Nagamoto,Takemura,Kitano,Komatsu,Sekiguchi,Tabusa,Mori,Tominaga,Yabuuchi
, p. 353 - 358 (2007/10/02)
Neutrophils have an important role in the self-defense systems of organisms through the production of superoxide. On the other hand, it has been proposed that abnormal amounts of superoxide produced by neutrophils are a serious factor in tissue injury. A series of novel thiazole derivatives was prepared and evaluated inhibitory effect on superoxide production by human neutrophils in vitro. Among these compounds, 6-[2-(3,4- diethoxyphenyl)thiazol-4-yl]-pyridine-2-carboxylic acid (OPC-6535) was selected as one of the most promising compounds. The synthesis and structure- activity relationships of these compounds are reported herein.
