14674-88-5Relevant articles and documents
Indium-mediated tandem dimerization and cyclization of nitrqones and aldimines to 3-arylaminodihydrobenzofurans under aqueous conditions
Jeevanandam, Arumugasamy,Ling, Yong-Chien
, p. 4361 - 4362 (2001)
Nitrones undergo deoxygenative reductive coupling and subsequent cyclization to 3-arylamino-2,3-dihydrobenzofuran derivatives in the presence of indium under aqueous conditions at ambient temperature in good yields.
Synthesis, characterization and anti-cancer studies of Mn(II), Cu(II), Zn(II) and Pt(II) dithiocarbamate complexes - crystal structures of the Cu(II) and Pt(II) complexes
Ajibade, Peter A.,Fatokun, Amos A.,Andrew, Fartisincha P.
, (2020)
Mn(II), Cu(II), Zn(II) and Pt(II) complexes of 2-((p-tolylamino)methyl)phenolyldithiocarbamate were synthesized and characterized by elemental analyses and spectroscopic techniques. Spectroscopic studies indicate four coordinate geometry around the metal(
Screening of simple carbohydrates as a renewable organocatalyst for the efficient construction of 1,3-benzoxazine scaffold
Y?ld?r?m, Ayhan,Kaya, Yunus,G?ker, Mustafa
, (2021/10/12)
A convenient protocol for the two component preparation of 1,3-benzoxazines by using several protected and unprotected carbohydrate molecules as organocatalysts have been developed which is broadly applicable to condensation reaction between variety of Ma
Metal-Free Diaryl Etherification of Tertiary Amines by Ortho-C(sp2)-H Functionalization for Synthesis of Dibenzoxazepines and -ones
Jamsheena, Vellekkatt,Mahesha, Chikkagundagal K.,Joy, M. Nibin,Lankalapalli, Ravi S.
supporting information, p. 6614 - 6617 (2017/12/26)
A phenyliodine(III) diacetate mediated umpolung reactivity of the tertiary amines with suitably substituted o-hydroxybenzyl and phenyl groups is exploited to facilitate o-C(sp2)-H functionalization to afford diaryl ethers. The presence of an o-
Influence of substituent on equilibrium of benzoxazine synthesis from Mannich base and formaldehyde
Deng, Yuyuan,Zhang, Qin,Zhou, Qianhao,Zhang, Chengxi,Zhu, Rongqi,Gu, Yi
, p. 18341 - 18348 (2014/09/30)
N-Substituted aminomethylphenol (Mannich base) and 3,4-dihydro-2H-3- substituted 1,3-benzoxazine (benzoxazine) were synthesized from substituted phenol (p-cresol, phenol, p-chlorophenol), substituted aniline (p-toluidine, aniline, p-chloroaniline) and formaldehyde to study influence of substituent on equilibrium of benzoxazine synthesis from Mannich base and formaldehyde. 1H-NMR and charges of nitrogen and oxygen atoms illustrate effect of substituent on reactivity of Mannich base, while oxazine ring stability is characterized by differential scanning calorimetry (DSC) and C-O bond order. Equilibrium constants were tested from 50 °C to 80 °C, and the results show that substituent attached to phenol or aniline has same impact on reactivity of Mannich base; however, it has opposite influence on oxazine ring stability and equilibrium constant. Compared with the phenol-aniline system, electron-donating methyl on phenol or aniline increases the charge of nitrogen and oxygen atoms in Mannich base. When the methyl group is located at para position of phenol, oxazine ring stability increases, and the equilibrium constant climbs, whereas when the methyl group is located at the para position of aniline, oxazine ring stability decreases, the benzoxazine hydrolysis tends to happen and equilibrium constant is significantly low. the Partner Organisations 2014.
Synthesis of 3-(4-Methyl-phenyl)-2-phenyl-3,4-dihydro-2H-benzo[e][1,3,2] oxazaphosphinine and Its Chalcogenides
Rani, Manju,Shukla, Davender Kumar,Khan, Arif Ali
, p. 3449 - 3451 (2013/05/09)
A simple method for the synthesis of 3-(4-methyl-phenyl)-2-phenyl-3,4- dihydro-2H-benzo[e][1,3,2]oxazaphosphinine (2) is described. P-Chalcogenides of (2) can be prepared by reacting with S, Se powder in toluene at 110°C. Whereas the tungsten pentacarbony
A quick route for the synthesis of 3-Aryl-3,4-dihydro-2H-benz[e]-1,3- oxazin-2-ones
Shukla, Davender Kumar,Rani, Manju,Khan, Arif Ali
, p. 4537 - 4540 (2013/06/27)
N-(2-Hydroxy)-benzyl-arylamines (1) gave substantially pure 3-aryl-3,4-dihydro-2H-benz[e]-1,3-oxazin-2-one 2 on cyclization with carbonyldiimidazole in DMSO in 20-30 min at 20-25 °C in excellent yields.
Synthesis and biological activity of some 3-aryl-3,4-dihydro-2h-benz[e]-1, 3-oxazines/6-bromo-3-aryl-3,4-dihydro-2h-benz[e]-1,3-oxazines
Shukla, Davender Kumar,Rani, Manju,Khan, Arif Ali,Tiwari, Kavita,Gupta, Rajinder K.
, p. 5921 - 5924 (2013/07/26)
N-(2-Hydroxy)-benzyl-arylamine (1) gives substantially pure 3-aryl-3,4-dihydro-2H-benz[e]-1,3-oxazines/6-bromo-3-aryl-3,4-dihydro-2H-benz[e] -1,3-oxazines (2) on cyclization with formaldehyde in methanol within 0.5-1.0 h at 65-68 C in excellent yields. Th
Efficient synthesis of 2,3-disubstituted-1,3-benzoxazines by chlorotrimethylsilane-mediated aza-acetalizations of aromatic aldehydes
Tang, Zilong,Zhu, Zhonghua,Yan, Lin,Chang, Shuhong,Liu, Hanwen
, p. 1116 - 1120 (2013/10/21)
A series of novel substituted 3,4-dihydro-2H-1,3-benzoxazines were prepared in moderate to good yields by aza-acetalizations of aromatic aldehydes with 2-(N-substituted aminomethyl)phenols in the presence of chlorotrimethylsilane or SnCl4. It w
SnCl4-catalyzed aza-acetalization of aromatic aldehydes: Synthesis of aryl substituted 3,4-dihydro-2H-1,3-benzoxazines
Tang, Zilong,Chen, Weiwen,Zhu, Zhonghua,Liu, Hanwen
, p. 1372 - 1383 (2012/04/04)
Stannic tetrachloride was an efficient Lewis acid catalyst for the aza-acetalization of aromatic aldehydes with o-arylaminomethyl phenols, and a series of novel aryl substituted 3,4-dihydro-2H-1,3-benzoxazines were prepared in good yields under mild condi
