148345-21-5

Basic information

• Product Name: (Z)-ethyl 2-benzoyl-3-(4-Methoxyphenyl)acrylate
• Synonyms: (Z)-ethyl 2-benzoyl-3-(4-Methoxyphenyl)acrylate
• CAS NO: 148345-21-5
• Molecular Formula: C₁₉H₁₈O₄
• Molecular Weight: 310.34382
• Mol File: 148345-21-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (Z)-ethyl 2-benzoyl-3-(4-Methoxyphenyl)acrylate(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-ethyl 2-benzoyl-3-(4-Methoxyphenyl)acrylate(148345-21-5)
• EPA Substance Registry System: (Z)-ethyl 2-benzoyl-3-(4-Methoxyphenyl)acrylate(148345-21-5)

Safety Data

• Hazardous Substances Data: 148345-21-5(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
(Z)-ethyl 2-benzoyl-3-(4-Methoxyphenyl)acrylate is used as a building block in organic synthesis for the creation of various pharmaceuticals and agrochemicals. Its unique structure allows for the development of a wide range of compounds with different biological activities and applications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (Z)-ethyl 2-benzoyl-3-(4-Methoxyphenyl)acrylate is used as an intermediate for the synthesis of drugs. Its chemical properties make it a valuable component in the development of new medications with potential therapeutic benefits.
Used in Agrochemical Industry:
(Z)-ethyl 2-benzoyl-3-(4-Methoxyphenyl)acrylate is also utilized as a starting material in the agrochemical industry for the production of pesticides and other agricultural chemicals. Its role in this industry is crucial for enhancing crop protection and yield.
Used in Light-Sensitive Applications:
Due to its photophysical properties, (Z)-ethyl 2-benzoyl-3-(4-Methoxyphenyl)acrylate is used in various light-sensitive applications, such as in the development of materials for photovoltaic cells or in the creation of light-responsive systems in different technological fields.

Upstream product

• 94-02-0 ethyl 3-oxo-3-phenylpropionate 
• 123-11-5 4-methoxy-benzaldehyde 
• 64967-44-8 (Z)-ethyl 3-acetyloxy-3-phenyl-2-propenoate 
• 2216-94-6 phenylpropynoic acid ethyl ester 
• 16089-66-0 C-(4-methoxyphenyl)-N-methyl nitrone 
• 148345-16-8 4-ethoxycarbonyl-3-(4'-methoxyphenyl)-2-methyl-5-phenyl-4-isoxazoline 
• 74-88-4 methyl iodide 

Downstream Products

• 105199-57-3 C₄₄H₃₄N₄O₆S₂ 
• 105199-52-8 5-Cyano-4-(4-methoxy-phenyl)-2-phenyl-6-thioxo-1,4,5,6-tetrahydro-pyridine-3-carboxylic acid ethyl ester 
• 188820-24-8 2-Amino-4-(4-methoxy-phenyl)-6-phenyl-1,4-dihydro-pyrimidine-5-carboxylic acid ethyl ester 
• 105199-42-6 Sodium; (4R,5S,6R)-3-cyano-5-ethoxycarbonyl-6-hydroxy-4-(4-methoxy-phenyl)-6-phenyl-1,4,5,6-tetrahydro-pyridine-2-thiolate 

Relevant articles and documents

Enzyme Promiscuity as a Remedy for the Common Problems with Knoevenagel Condensation

A new protocol based on lipase-catalyzed tandem reaction toward α,β-enones/enoesters is presented. For the synthesis of the desired products the tandem process based on enzyme-catalyzed hydrolysis and Knoevenagel reaction starting from enol acetates and aldehyde is developed. The relevant impact of the reaction conditions including organic solvent, enzyme type, and temperature on the course of the reaction was revealed. It was shown that controllable release of the active methylene compound from the corresponding enol carboxylate ensured by enzymatic reaction diminishes significantly the formation of the unwanted co-products. Furthermore, this protocol was extended by including a second tandem chemoenzymatic transformation engaging various aldehyde precursors. After a careful optimization of the reaction conditions, the target products were obtained with yields up to 86 % and with excellent E/Z-selectivity.

Cationic vanadium(IV) complexes as efficient catalysts for nazarov cyclizations

Vanadium(IV) species generated in situ from V(salen)Cl2 complexes (1) by reaction with 2 equiv. of AgSbF6 are effective catalysts for Nazarov cyclizations. Thus, dialkenyl ketones bearing α-ester groups are efficiently converted to c

Synthesis of Ethyl 2-Aminodihydro-5-pyrimidinecarboxylate Derivatives and 3,7-Diethoxycarbonyl-4,6-dihydro-2,4,6,8-tetraaryl-lH-pyrimido[1,2-a]pyrimidines

Reactions of ethyl 3-aryl-2-benZoylpropenoateS 1 with guanidine and N-alkyl(or benzyl)guanidines have been investigated. Ethyl 2-aminodihydro-5-pyrimidinecarboxylate derivatives 3, 4 or 5 and 3,7-diethoxycarbonyl-4,6-dihydro-2,4,6,8-tetraaryl-lH-pyrimido[

RING-OPENING OF 4-ISOXAZOLINES: COMPETITIVE FORMATION OF ENAMINO DERIVATIVES AND α,β-ENONES

Ring-opening of 3-substituted 4-isoxazolines, proceeding through the intermediate isoxazolinium salts, follows two competing reaction pathways leading to α,β-enones and enamines respectively.The rearrangement courses can be controlled as a function of substitution pattern and experimental conditions.