148505-45-7

Basic information

• Product Name: 4-(4'-NITROPHENOXY)PIPERIDINE HYDROCHLORIDE
• Synonyms: 4-(4'-NITROPHENOXY)PIPERIDINE HYDROCHLORIDE;4-(4-NITRO-PHENOXY)-PIPERIDINE HYDROCHLORIDE;4-(4-Nitrophenoxy)piperidine HCl;PIPER,4-(4-NITROPHENOXY)-,HYDROCHLORIDE (1:1)
• CAS NO: 148505-45-7
• Molecular Formula: C₁₁H₁₄N₂O₃*ClH
• Molecular Weight: 258.7
• Mol File: 148505-45-7.mol

Chemical Properties

• Melting Point: 228-229°
• Appearance: /
• CAS DataBase Reference: 4-(4'-NITROPHENOXY)PIPERIDINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4'-NITROPHENOXY)PIPERIDINE HYDROCHLORIDE(148505-45-7)
• EPA Substance Registry System: 4-(4'-NITROPHENOXY)PIPERIDINE HYDROCHLORIDE(148505-45-7)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 148505-45-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4-(4'-NITROPHENOXY)PIPERIDINE HYDROCHLORIDE is used as an intermediate in the synthesis of certain drugs for its potential to contribute to the development of new medications.
Used in Agrochemical Industry:
4-(4'-NITROPHENOXY)PIPERIDINE HYDROCHLORIDE is used as an intermediate in the synthesis of agrochemicals, potentially aiding in the creation of new compounds for agricultural applications.
Safety Precautions:
Due to its potential health hazards, 4-(4'-NITROPHENOXY)PIPERIDINE HYDROCHLORIDE should be handled and stored according to proper safety guidelines. It is recommended for use only by qualified individuals in a controlled laboratory environment to ensure safety and effectiveness in its applications.

Upstream product

• 138227-58-4 1-Acetyl-4-(4-nitrophenyloxy)-piperidine 
• 5382-16-1 4-HYDROXYPIPERIDINE 
• 138227-62-0 tert-butyl 4-(4-nitrophenoxy)piperidine-1-carboxylate 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 
• 350-46-9 4-Fluoronitrobenzene 

Downstream Products

• 148505-46-8 N-2-(4-nitrophenoxy)ethyl-4-(4-nitrophenoxy)piperidine 
• 862310-27-8 1-cyclopentyl -4-(4-nitrophenoxy)piperidine 
• 862314-14-5 1-cyclopropyl-4-(4-nitrophenoxy)piperidine 
• 287952-56-1 1-(methylsulfonyl)-4-(4-nitrophenoxy)piperidine 
• 287952-57-2 methyl [[4-(4-nitrophenoxy)-1-piperidinyl]sulfonyl]acetate 

Relevant articles and documents

COMPOUNDS AS NEURONAL HISTAMINE RECEPTOR-3 ANTAGONISTS AND USES THEREOF

The present invention relates compounds of Formula (A) as H3R antagonists, as well as their preparation and uses, and further relates pharmaceutical compositions comprising these compounds and their uses as modulators of Histamine 3 Receptor (H3R) functions. The present invention also relates to the uses of the compounds or pharmaceutical compositions in treating or preventing certain disorders and diseases which relate to H3R functions in humans.

CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS

Chemical entities that are kinase inhibitors, pharmaceutical compositions and methods of treatment of cancer are described.

Sulfamato hydroxamic acid metalloprotease inhibitor

A sulfamato hydroxamic acid compound that, inter alia, inhibits matrix metalloprotease (mmp) activity is disclosed as are a process for preparing the same, intermediate compounds useful in those syntheses, and a treatment process that comprises administering a contemplated sulfamato hydroxamic acid compound in a MMP enzyme-inhibiting effective amount to a host having a condition associated with pathological matrix metalloprotease activity.

Piperidinyl and piperazinyl derivatives

Compounds of the formula: STR1 in which R1 is alkylsulfonamido of 1 to 6 carbon atoms, arylsulfonamido of 6 to 10 carbon atoms, --NO2,--CN, 1-imidazolyl or 1,2,4-triazol-1-yl; Y is STR2 --CH2 --, --O--, --S--, or --SO2 --; X is --CH= or --N=; R2 is hydrogen when n is 0, otherwise it is hydrogen or --OH; n is one of the integers 0, 1, 2, 3, 4, 5 or 6; A is STR3 where R3 is alkylsulfonamido of 1 to 6 carbons atoms, arylsulfonamido of 6 to 10 carbon atoms, --NO2, --CN, 1-imidazolyl or 1,2,4-triazol-1-yl; or STR4 where R4 is hydrogen or alkyl of 1 to 6 carbon atoms; with the provisos that; a) X is --CH= when Y is STR5 --O-- or --S-- and when Y is STR6 and R2 is --OH; b) X is --N= when A is STR7 c) A is STR8 when Y is --S-- or --SO2 -- and X is --CH=, and their pharmaceutically acceptable salts are Class III antiarrhythmic agents.