148579-93-5

Basic information

• Product Name: 4-ForMyl-2-nitrophenyl β-D-Glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate
• Synonyms: 4-ForMyl-2-nitrophenyl β-D-Glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate;MHAQOFAFDHVKQE-UHFFFAOYSA-N
• CAS NO: 148579-93-5
• Molecular Formula: C₂₀H₂₁NO₁₃
• Molecular Weight: 483.37964
• Product Categories: Aromatics, Carbohydrates & Derivatives
• Mol File: 148579-93-5.mol

Chemical Properties

• Melting Point: 180-182 °C
• Boiling Point: 582.6±50.0 °C(Predicted)
• Appearance: /
• Density: 1.44±0.1 g/cm3(Predicted)
• CAS DataBase Reference: 4-ForMyl-2-nitrophenyl β-D-Glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ForMyl-2-nitrophenyl β-D-Glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate(148579-93-5)
• EPA Substance Registry System: 4-ForMyl-2-nitrophenyl β-D-Glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate(148579-93-5)

Safety Data

• Hazardous Substances Data: 148579-93-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4-ForMyl-2-nitrophenyl β-D-Glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate is used as a key intermediate in the synthesis of Camptothecin-based anticancer therapy. Camptothecin is a potent chemotherapeutic agent that has demonstrated significant efficacy against various types of cancer, including colorectal, ovarian, and lung cancer. The compound's unique structure enables the development of Camptothecin analogs with improved pharmacological properties, such as enhanced solubility, stability, and bioavailability.
In the synthesis of Camptothecin-based anticancer therapy, 4-ForMyl-2-nitrophenyl β-D-Glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate plays a crucial role in the formation of the final therapeutic agent. Its chemical reactivity allows for the introduction of various functional groups and modifications, which can lead to the development of more effective and targeted cancer treatments. By utilizing 4-ForMyl-2-nitrophenyl β-D-Glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate as a starting material, researchers can explore new strategies for the design and synthesis of novel anticancer drugs, potentially improving patient outcomes and overall survival rates.

Upstream product

• 3011-34-5 4-hydroxy-3-nitrobenzaldehyde 
• 3082-95-9 2,3,4-Tri-O-acetyl-β-D-glucopyranuronic acid methylester 
• 3082-96-0 methyl 1,2,3,4-tetra-O-acetyl-α,β-D-glucopyranosyluronate 
• 90151-04-5 4-hydroxy-2-nitrobenzaldehyde 
• 21085-72-3 1-bromo-2,3,4-tri-O-acetyl-α-D-glucuronic acid methyl ester 
• 6919-98-8 2,3,4-tri-O-acetyl-1-bromo-1-deoxy-β-D-glucopyranuronic acid methy ester 
• 7355-18-2 (2S,3S,4S,5R,6S)-3,4,5,6-Tetraacetoxy-tetrahydro-pyran-2-carboxylic acid methyl ester 
• 63-29-6 D-glucurono-6,3-lactone 
• 57820-69-6 (3R,4S,5S,6S)-2-bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate 

Downstream Products

• 1018932-83-6 methyl 1-O-(4-methanesulfonyloxymethyl-2-nitrophenyl)-2,3,4-tri-O-acetyl-β-D-glucopyranuronate 
• 1310012-58-8 10-[4-O-(methyl-2,3,4-tri-O-acetyl-β-D-glucopyranuronate)-3-nitrobenzyloxy]-5,6-dihydro-4H-benzo[de]quinoline-camptothecin 
• 1310012-59-9 5,6-dihydro-4H-benzo[de]quinoline camptothecin-β-D-glucuronide methyl ester 
• 1310012-57-7 5,6-dihydro-4H-benzo[de]quinoline camptothecin-β-D-glucuronide 
• 1353003-36-7 allyl 1-(4-(O-4-nitrophenyloxycarbonyl)methyl-2-nitrophenyl)-2,3,4-tri-O-allyloxycarbonyl-β-D-glucuronate 
• 1353003-35-6 allyl 1-(4-hydroxymethyl-2-nitrophenyl)-2,3,4-tri-O-allyloxycarbonyl-β-D-glucuronate 
• 1353003-46-9 allyl 1-(4-(tert-butyldimethylsilyloxy)methyl-2-nitrophenyl)-2,3,4-tri-O-allyloxycarbonyl-β-D-glucuronate 
• 1353003-45-8 allyl 1-(4-(tert-butyldimethylsilyloxy)methyl-2-nitrophenyl)-β-D-glucuronate 
• 1353003-43-6 methyl 1-(4-(tert-butyldimethylsilyloxy)methyl-2-nitrophenyl)-2,3,4-tri-O-acetyl-β-D-glucuronate 
• 148580-25-0 N-[4-O-β-D-glucuronyl-3-nitrobenzyloxycarbonyl]doxorubicin 
• 148580-01-2 (2S,3S,4S,5R,6S)-3,4,5-Triacetoxy-6-[2-nitro-4-(4-nitro-phenoxycarbonyloxymethyl)-phenoxy]-tetrahydro-pyran-2-carboxylic acid methyl ester 
• 637330-36-0 benzyl {[2-nitro-4-(O-tert-butyldiphenylsilylmethyl)phenyl]-2,3,4-tri-(O-tert-butyldimethylsilyl)-β-D-glucopyranosid}uronate 
• 637330-39-3 N,N'-dimethyl-N-benzyl-[4-(2,3,4-tri-O-tert-butyldimethylsilyl-β-D-glucopyranosyl)uronate-3-nitrobenzoyloxycarbonyl]-N'-(tert-butoxycarbonyl)ethylenediamine 
• 637330-41-7 N,N'-dimethyl-N-benzyl-[4-(2,3,4-tri-O-tert-butyldimethylsilyl-β-D-glucopyranosyl)uronate-3-nitrobenzoyloxycarbonyl]ethylenediamine carbamoyl chloride 

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