149139-41-3

Basic information

• Product Name: 2-Propenenitrile,3-(dimethylamino)-2-formyl-,(E)-(9CI)
• Synonyms: 2-Propenenitrile,3-(dimethylamino)-2-formyl-,(E)-(9CI);(E)-3-(DIMETHYLAMINO)-2-FORMYLACRYLONITRILE
• CAS NO: 149139-41-3
• Molecular Formula: C₆H₈N₂O
• Molecular Weight: 124.14
• Product Categories: AMINETERTIARY
• Mol File: 149139-41-3.mol

Chemical Properties

• Boiling Point: 413.2±30.0 °C(Predicted)
• Appearance: /
• Density: 1.043±0.06 g/cm3(Predicted)
• PKA: 1.83±0.70(Predicted)
• CAS DataBase Reference: 2-Propenenitrile,3-(dimethylamino)-2-formyl-,(E)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenenitrile,3-(dimethylamino)-2-formyl-,(E)-(9CI)(149139-41-3)
• EPA Substance Registry System: 2-Propenenitrile,3-(dimethylamino)-2-formyl-,(E)-(9CI)(149139-41-3)

Safety Data

• Hazardous Substances Data: 149139-41-3(Hazardous Substances Data)

Usage

Functional Groups

Nitrile Group ( -C \equiv N )
Formyl Group ( -CHO )

Applications

Organic Synthesis: Serves as a crucial building block.
Pharmaceutical Industry: Potential use as a chemical intermediate.

Versatility

Contains functional groups conducive to various reactions.
Potential applications in medicine, agriculture, and materials science.

Safety Considerations

Caution Required: Due to potential health hazards.
Proper Handling Necessary: Ensuring safety protocols during usage and storage.

Upstream product

• 35520-41-3 trans-3-dimethylaminoacrylonitrile 
• 6162-76-1 cyanoacetaldehyde 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 

Downstream Products

• 16849-88-0 1-(dimethylamine)-2,2-dicyanoethylene 
• 77017-54-0 2-(4-hydroxy-phenyl)-pyrimidine-5-carbonitrile 
• 712-72-1 1-(4-methylphenyl)-1H-pyrazole-4-carbonitrile 
• 66121-71-9 1-methyl-1H-pyrazole-4-carbonitrile 
• 102539-56-0 1-p-nitrophenylpyrazole-4-carbonitrile 
• 709-04-6 1-phenyl-1H-pyrazole-4-carbonitrile 
• 105161-35-1 4-amino-2-sulfanylpyrimidine-5-carbaldehyde 
• 31108-57-3 1H-pyrazole-4-carbonitrile 
• 1753-48-6 2-aminopyrimidine-5-carbonitrile 
• 154867-26-2 2-formyl-3-(3-benzylureido)propenenitrile 

Relevant articles and documents

Cyanoacetaldehyde - New Synthetic Applications of an Old Compound Syntheses with Nitriles, XCI

Various reactions of cyanoacetaldehyde (1), freshly prepared by ozonization of (E)-1,4-dicyano-2-butene or allylcyanide, are described.Thus, conversion of 1 with anilines gave β-phenylaminoacrylonitriles 2a-e.Reaction of 1 with hydrazines led to the corresponding hydrazones 3a-e, which could be cyclized under alkaline conditions to 5-aminopyrazoles 4a-d.An aldol-type condensation product 5a could be obtained by reaction of 1 with sodiumphenoxide.Treatment of 1 with dimethylformamide-dimethylacetal led to the formation of (E)-3-dimethylamino-2-formylpropenenitrile (6), a very useful synthon in synthetic chemistry.For the determination of the structure of 6 the method of steady state diffferential NOEs was used.Reaction of 6 with hydrazines gave 1-substituted-4-cyanopyrazoles 7a-k. Keywords.Cyanoacetaldehyde; Hydrazones; Cyanopyrazoles; Aminopyrazoles.

Process for producing dialkyl aminoacrylonitrile

A process for producing a dialkyl aminoacrylonitrile by treating dimethylaminopropionitrile with a hydrogen acceptor in the presence of a dehydrogenation catalyst. The dialkylaminoacrylonitrile thus produced is converted to aminomethylene malonitrile, a known intermediate for thiamine.