150670-63-6

Basic information

• Product Name: 3,4-dihydrocyclopenta[b]indol-2(1H)-one
• Synonyms: 3,4-dihydrocyclopenta[b]indol-2(1H)-one
• CAS NO: 150670-63-6
• Molecular Formula: C₁₁H₉NO
• Molecular Weight: 171.19526
• Mol File: 150670-63-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,4-dihydrocyclopenta[b]indol-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-dihydrocyclopenta[b]indol-2(1H)-one(150670-63-6)
• EPA Substance Registry System: 3,4-dihydrocyclopenta[b]indol-2(1H)-one(150670-63-6)

Safety Data

• Hazardous Substances Data: 150670-63-6(Hazardous Substances Data)

Upstream product

• 7394-63-0 3-(prop-2-yn-1-yl)-1H-indole 
• 87-51-4 indole-3-acetic acid 
• 50720-05-3 indolyl acetyl chloride 
• 32588-36-6 indolylacetic acid 
• 150649-16-4 1-diazo-3-(1H-indol-3-yl)propan-2-one 

Relevant articles and documents

Synthesis of a Novel, Conformationally Restricted Analog of Tryptophan

The synthesis of a new, conformationally restrained analogue of tryptophan, 1,2,3,4-tetrahydro-2-amino-2-carboxy-cyclopentindole (5) is described.The key step involves the BF3*Et2O catalyzed intramolecular cyclization of α-diazoketone 2b into the 1,2,3,4-tetrahydro-cyclopentindol-2-one (3).Key Words: Conformationally restrained tryptophan analog, diazoketone-BF3*Et2O catalyzed intramolecular cyclization, cycloalkindolones.

Biarylphosphonite gold(I) complexes as superior catalysts for oxidative cyclization of propynyl arenes into indan-2-ones

Striking gold: A series of variously functionalized propynyl arenes was smoothly converted into indan-2-ones by a new gold(I)-catalyzed oxidative cyclization process. [LAu]NTf2 (Tf=trifluoromethanesulfonyl) is a superior catalyst both in terms of yield and kinetics for the present transformation. Copyright

Rhodium(II) catalyzed intramolecular insertion of carbenoids derived from 2-pyrrolyl and 3-indolyl α-diazo-β-ketoesters and α-diazoketones

α-Diazo-β-ketoesters and α-diazoketones derived from 2-pyrrolylacetic, 2-pyrrolylpropionic, 3-indolylacetic and 3-indolylpropionic acids afforded carbenoid derived cyclization products on treatment with catalytic rhodium(II) acetate.

Intramolecular carbenoid insertions: The reactions of α-diazoketones derived from pyrrolyl and indolyl carboxylic acids with rhodium(II) acetate

α-Diazoketones derived from pyrrolyl- and indolyl-carboxylic acids were prepared and their Rh2(OAc)4 catalyzed decomposition chemistry was studied. These reactions generally resulted in the alkylation of the heteroaromatic system by the ketocarbenoid and in some instances the systems underwent CH or NH insertions. Evidence that some of these reactions proceed via a cyclopropane intermediate is presented. The methodology described provides facile access to fused pyrrolyl- or indolyl-cycloalkanone systems wherein the carbonyl is beta to the heteroaromatic system. (C) 2000 Elsevier Science Ltd.